NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DQL59_RS08435	Genome accession	NZ_LS483326
Coordinates	1674970..1675566 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain NCTC12045
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1669970..1680566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL59_RS08400 (NCTC12045_01655)	-	1670031..1670336 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DQL59_RS08405 (NCTC12045_01656)	ruvX	1670348..1670767 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DQL59_RS08410 (NCTC12045_01657)	-	1670764..1671033 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DQL59_RS08415 (NCTC12045_01658)	spx	1671146..1671544 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DQL59_RS08420 (NCTC12045_01659)	recA	1671835..1672971 (-)	1137	WP_002992179.1	recombinase RecA	Machinery gene
DQL59_RS08425 (NCTC12045_01660)	cinA	1673060..1674331 (-)	1272	WP_038433761.1	competence/damage-inducible protein A	Machinery gene
DQL59_RS08430 (NCTC12045_01661)	-	1674400..1674960 (-)	561	WP_023610776.1	DNA-3-methyladenine glycosylase I	-
DQL59_RS08435 (NCTC12045_01662)	ruvA	1674970..1675566 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
DQL59_RS08440 (NCTC12045_01663)	-	1675568..1676788 (-)	1221	WP_002992187.1	MDR family MFS transporter	-
DQL59_RS08445 (NCTC12045_01664)	hexB	1676799..1678781 (-)	1983	WP_002992189.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQL59_RS08450 (NCTC12045_01665)	-	1678876..1680021 (-)	1146	WP_111681402.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=1017439 DQL59_RS08435 WP_002992186.1 1674970..1675566(-) (ruvA) [Streptococcus pyogenes strain NCTC12045]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=1017439 DQL59_RS08435 WP_002992186.1 1674970..1675566(-) (ruvA) [Streptococcus pyogenes strain NCTC12045]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAACAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG1017439