Detailed information NTG1017331

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL79_RS09140
• Genome accession: NZ_LS483324
• Coordinates: 1819988..1820977 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain NCTC10344
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1814988..1825977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL79_RS09125 (NCTC10344_01722)	acsA	1816189..1817895 (-)	1707	WP_000862084.1	acetate--CoA ligase	-
DQL79_RS09130 (NCTC10344_01723)	-	1818064..1818696 (+)	633	WP_001016008.1	GNAT family N-acetyltransferase	-
DQL79_RS09135 (NCTC10344_01724)	-	1818721..1819890 (+)	1170	WP_001184008.1	acetoin utilization protein AcuC	-
DQL79_RS09140 (NCTC10344_01725)	ccpA	1819988..1820977 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
DQL79_RS09145	-	1821050..1821163 (-)	114	WP_001788994.1	hypothetical protein	-
DQL79_RS09150 (NCTC10344_01726)	-	1821517..1822608 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
DQL79_RS09155	-	1823064..1823147 (-)	84	WP_031797498.1	hypothetical protein	-
DQL79_RS09160 (NCTC10344_01727)	-	1823303..1824655 (-)	1353	WP_000193946.1	hypothetical protein	-
DQL79_RS09165 (NCTC10344_01728)	-	1824729..1825220 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=1017331 DQL79_RS09140 WP_000219066.1 1819988..1820977(-) (ccpA) [Staphylococcus aureus strain NCTC10344]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=1017331 DQL79_RS09140 WP_000219066.1 1819988..1820977(-) (ccpA) [Staphylococcus aureus strain NCTC10344]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATCAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462