Detailed information NTG1017324

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ABHI20_RS02225
• Genome accession: NZ_CP160045
• Coordinates: 413844..414845 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes M1 GAS strain SF370
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 408844..419845

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABHI20_RS02200 (ABHI20_02200)	-	409518..410201 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
ABHI20_RS02205 (ABHI20_02205)	-	410412..411338 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ABHI20_RS02210 (ABHI20_02210)	-	411483..411860 (-)	378	WP_002985686.1	VOC family protein	-
ABHI20_RS02215 (ABHI20_02215)	-	411871..412536 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
ABHI20_RS02220 (ABHI20_02220)	-	412585..413670 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
ABHI20_RS02225 (ABHI20_02225)	ccpA	413844..414845 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ABHI20_RS02230 (ABHI20_02230)	-	414976..415974 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ABHI20_RS02235 (ABHI20_02235)	-	415976..417310 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ABHI20_RS02240 (ABHI20_02240)	thrS	417732..419675 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1017324 ABHI20_RS02225 WP_002985680.1 413844..414845(+) (ccpA) [Streptococcus pyogenes M1 GAS strain SF370]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1017324 ABHI20_RS02225 WP_002985680.1 413844..414845(+) (ccpA) [Streptococcus pyogenes M1 GAS strain SF370]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559