Detailed information NTG1017309

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ABHI20_RS00680
• Genome accession: NZ_CP160045
• Coordinates: 104753..105187 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes M1 GAS strain SF370
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99753..110187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABHI20_RS00650 (ABHI20_00650)	-	101422..101787 (+)	366	WP_002986560.1	DUF1033 family protein	-
ABHI20_RS00655 (ABHI20_00655)	comYA	101880..102818 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
ABHI20_RS00660 (ABHI20_00660)	comYB	102754..103788 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABHI20_RS00665 (ABHI20_00665)	comYC	103790..104116 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ABHI20_RS00670 (ABHI20_00670)	comGD	104091..104519 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ABHI20_RS00675 (ABHI20_00675)	comGE	104476..104760 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ABHI20_RS00680 (ABHI20_00680)	comYF	104753..105187 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABHI20_RS00685 (ABHI20_00685)	comGG	105171..105497 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
ABHI20_RS00690 (ABHI20_00690)	comYH	105595..106548 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
ABHI20_RS00695 (ABHI20_00695)	-	106607..107803 (+)	1197	WP_010921803.1	acetate kinase	-
ABHI20_RS00700 (ABHI20_00700)	-	107990..108298 (+)	309	WP_010921804.1	hypothetical protein	-
ABHI20_RS00705 (ABHI20_00705)	proC	108381..109151 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=1017309 ABHI20_RS00680 WP_010921800.1 104753..105187(+) (comYF) [Streptococcus pyogenes M1 GAS strain SF370]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1017309 ABHI20_RS00680 WP_010921800.1 104753..105187(+) (comYF) [Streptococcus pyogenes M1 GAS strain SF370]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389