Detailed information NTG1017145

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL05_RS06605
• Genome accession: NZ_LS483322
• Coordinates: 1308769..1309770 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain NCTC12066
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1303769..1314770

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL05_RS06590 (NCTC12066_01310)	thrS	1303939..1305882 (-)	1944	WP_111692045.1	threonine--tRNA ligase	-
DQL05_RS06595 (NCTC12066_01312)	-	1306304..1307638 (-)	1335	WP_030126779.1	glycosyltransferase family 4 protein	-
DQL05_RS06600 (NCTC12066_01313)	-	1307640..1308638 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL05_RS06605 (NCTC12066_01314)	ccpA	1308769..1309770 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL05_RS06610 (NCTC12066_01315)	-	1309944..1311029 (+)	1086	WP_030126780.1	aminopeptidase P family protein	-
DQL05_RS06615 (NCTC12066_01316)	-	1311078..1311743 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL05_RS06620 (NCTC12066_01317)	-	1311754..1312131 (+)	378	WP_002985686.1	VOC family protein	-
DQL05_RS06625 (NCTC12066_01318)	-	1312276..1313202 (+)	927	WP_030126781.1	glycosyltransferase family 2 protein	-
DQL05_RS06630 (NCTC12066_01319)	-	1313413..1314096 (+)	684	WP_012560521.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1017145 DQL05_RS06605 WP_002985680.1 1308769..1309770(-) (ccpA) [Streptococcus pyogenes strain NCTC12066]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1017145 DQL05_RS06605 WP_002985680.1 1308769..1309770(-) (ccpA) [Streptococcus pyogenes strain NCTC12066]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559