Detailed information NTG1011484

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ABS957_RS28375
• Genome accession: NZ_CP158482
• Coordinates: 5924597..5925934 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 1485138
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5919597..5930934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABS957_RS28350 (ABS957_28350)	pgeF	5919740..5920468 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ABS957_RS28355 (ABS957_28355)	rluD	5920465..5921427 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ABS957_RS28360 (ABS957_28360)	-	5921573..5922598 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ABS957_RS28365 (ABS957_28365)	-	5922755..5923000 (+)	246	WP_003102591.1	PP0621 family protein	-
ABS957_RS28370 (ABS957_28370)	pilS	5922990..5924582 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ABS957_RS28375 (ABS957_28375)	pilR	5924597..5925934 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ABS957_RS28380 (ABS957_28380)	thiO	5925980..5927074 (-)	1095	WP_023089635.1	glycine oxidase ThiO	-
ABS957_RS28385 (ABS957_28385)	-	5927209..5927718 (+)	510	WP_003112829.1	Tfp pilus assembly protein FimT/FimU	-
ABS957_RS28390 (ABS957_28390)	-	5927824..5928330 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ABS957_RS28395 (ABS957_28395)	pilV	5928321..5928878 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ABS957_RS28400 (ABS957_28400)	pilW	5928875..5929699 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ABS957_RS28405 (ABS957_28405)	pilX	5929696..5930283 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1011484 ABS957_RS28375 WP_003094694.1 5924597..5925934(+) (pilR) [Pseudomonas aeruginosa strain 1485138]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1011484 ABS957_RS28375 WP_003094694.1 5924597..5925934(+) (pilR) [Pseudomonas aeruginosa strain 1485138]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384