Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   H1W90_RS00345 Genome accession   NZ_LR822033
Coordinates   60667..61257 (+) Length   196 a.a.
NCBI ID   WP_002949053.1    Uniprot ID   Q5M6H5
Organism   Streptococcus thermophilus isolate STH_CIRM_1048     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 55667..66257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W90_RS10345 - 56797..57252 (-) 456 Protein_42 DUF3021 domain-containing protein -
  H1W90_RS00325 (STHERMO_0058) - 57249..57640 (-) 392 Protein_43 LytTR family DNA-binding domain-containing protein -
  H1W90_RS00330 (STHERMO_0059) - 57864..58169 (+) 306 WP_011225281.1 hypothetical protein -
  H1W90_RS00335 (STHERMO_0060) hexB 58221..60164 (+) 1944 WP_173940305.1 DNA mismatch repair endonuclease MutL Machinery gene
  H1W90_RS00340 (STHERMO_0061) - 60294..60515 (+) 222 WP_002949052.1 hypothetical protein -
  H1W90_RS00345 (STHERMO_0062) ruvA 60667..61257 (+) 591 WP_002949053.1 Holliday junction branch migration protein RuvA Machinery gene
  H1W90_RS00350 - 61264..61818 (+) 555 Protein_48 DNA-3-methyladenine glycosylase I -
  H1W90_RS00355 (STHERMO_0065) cinA 61914..63185 (+) 1272 WP_011225285.1 competence/damage-inducible protein A Machinery gene
  H1W90_RS00360 (STHERMO_0066) recA 63221..64360 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  H1W90_RS00365 (STHERMO_0067) spx 64537..64935 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21699.98 Da        Isoelectric Point: 5.2834

>NTDB_id=1010886 H1W90_RS00345 WP_002949053.1 60667..61257(+) (ruvA) [Streptococcus thermophilus isolate STH_CIRM_1048]
MYDYIKGTLVKITAKHIVIETNGLGYIVTVANPYSFSDQMNQTIQVYLHQVIRDDAHLLFGFHTEDEKEVFLKLISVSGI
GPTTALAIVAVDDNQGLVAAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFAELPAETTNTTANQTAGNQQLDEAMEALL
ALGYKSTELKKVKAFFEDTNETAEQYIKSALKMLMK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1010886 H1W90_RS00345 WP_002949053.1 60667..61257(+) (ruvA) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGTATGATTATATCAAGGGCACCCTAGTAAAAATCACAGCCAAACACATTGTCATAGAAACAAATGGTCTAGGATATAT
TGTCACTGTGGCTAATCCCTACAGCTTTTCTGATCAAATGAATCAGACTATCCAAGTGTATCTTCATCAAGTTATTAGAG
ATGATGCCCACCTACTTTTTGGTTTTCATACTGAAGATGAGAAAGAAGTTTTTCTTAAGTTGATTTCTGTTTCTGGGATA
GGTCCGACGACTGCTCTAGCCATAGTGGCTGTGGATGATAATCAGGGACTTGTTGCTGCTATTGATAATAGTGACATCAA
ATACCTGATGAAATTTCCAAAGATTGGTAAAAAGACTGCTCAACAAATGGTTCTTGATCTGGCAGGAAAATTTGCAGAGT
TACCAGCAGAAACGACCAATACTACGGCAAATCAGACTGCAGGAAATCAACAGTTGGATGAAGCTATGGAAGCTTTGCTT
GCTCTTGGGTACAAATCCACAGAGCTTAAGAAAGTGAAAGCCTTCTTTGAGGATACCAATGAAACGGCAGAGCAATATAT
TAAGTCCGCTCTTAAAATGTTGATGAAGTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(151-195)

RuvA N terminal domain (RuvA_N)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M6H5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66

100

0.673
  ruvA Streptococcus pneumoniae R6

66

100

0.673
  ruvA Streptococcus pneumoniae D39

66

100

0.673
  ruvA Bacillus subtilis subsp. subtilis str. 168

42.647

100

0.444

Multiple sequence alignment