Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   H1X08_RS10550 Genome accession   NZ_LR822025
Coordinates   290996..291799 (-) Length   267 a.a.
NCBI ID   WP_232086948.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_961     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 285996..296799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X08_RS01520 (STHERMO_0315) comA/nlmT 287266..289419 (+) 2154 WP_180482397.1 peptide cleavage/export ABC transporter Regulator
  H1X08_RS01525 (STHERMO_0316) comB 289435..290802 (+) 1368 WP_180482398.1 bacteriocin secretion accessory protein Regulator
  H1X08_RS01530 (STHERMO_0317) - 290817..290978 (+) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1X08_RS10550 comD/blpH 290996..291799 (-) 804 WP_232086948.1 ATP-binding protein Regulator
  H1X08_RS01540 (STHERMO_0319) - 292330..293067 (-) 738 WP_180482400.1 LytR/AlgR family response regulator transcription factor -
  H1X08_RS01545 (STHERMO_0320) - 293318..293494 (+) 177 WP_180482401.1 Blp family class II bacteriocin -
  H1X08_RS01550 (STHERMO_0321) - 293513..293713 (+) 201 WP_011681569.1 hypothetical protein -
  H1X08_RS01555 (STHERMO_0322) - 294069..294299 (+) 231 WP_011226494.1 bacteriocin class II family protein -
  H1X08_RS01560 (STHERMO_0323) - 294306..294467 (+) 162 WP_011681568.1 hypothetical protein -
  H1X08_RS11190 - 295323..295724 (+) 402 WP_011226490.1 hypothetical protein -
  H1X08_RS01565 (STHERMO_0328) - 295975..296217 (+) 243 WP_180482402.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30641.87 Da        Isoelectric Point: 4.6583

>NTDB_id=1010240 H1X08_RS10550 WP_232086948.1 290996..291799(-) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_961]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=1010240 H1X08_RS10550 WP_232086948.1 290996..291799(-) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.583

95.131

0.367