Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   H0511_RS07875 Genome accession   NZ_LR822017
Coordinates   1541903..1542634 (+) Length   243 a.a.
NCBI ID   WP_179973976.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1536903..1547634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS07835 (STHERMO_1766) - 1537707..1537949 (-) 243 WP_096811635.1 Blp family class II bacteriocin -
  H0511_RS07840 (STHERMO_1767) - 1538159..1538338 (-) 180 WP_011681564.1 hypothetical protein -
  H0511_RS07845 (STHERMO_1768) - 1538367..1538759 (-) 393 WP_003094909.1 hypothetical protein -
  H0511_RS07850 (STHERMO_1769) cipB 1538771..1539010 (-) 240 WP_011681565.1 Blp family class II bacteriocin Regulator
  H0511_RS07855 (STHERMO_1771) - 1539366..1539566 (-) 201 WP_011681569.1 hypothetical protein -
  H0511_RS07860 (STHERMO_1772) - 1539585..1539761 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  H0511_RS10500 (STHERMO_1773) - 1540012..1540413 (-) 402 WP_011226490.1 hypothetical protein -
  H0511_RS07865 (STHERMO_1776) - 1541268..1541411 (-) 144 WP_014608661.1 hypothetical protein -
  H0511_RS07870 (STHERMO_1777) - 1541418..1541648 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  H0511_RS07875 (STHERMO_1778) comE/blpR 1541903..1542634 (+) 732 WP_179973976.1 LytR/AlgR family response regulator transcription factor Regulator
  H0511_RS10155 (STHERMO_1780) comD/blpH 1543170..1543973 (+) 804 WP_228024405.1 ATP-binding protein Regulator
  H0511_RS07885 (STHERMO_1781) - 1543991..1544152 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H0511_RS07890 (STHERMO_1782) comB 1544167..1545534 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27788.14 Da        Isoelectric Point: 7.5084

>NTDB_id=1009779 H0511_RS07875 WP_179973976.1 1541903..1542634(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_336]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDKFFLYKTESQLINLPMDQILYLSS
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1009779 H0511_RS07875 WP_179973976.1 1541903..1542634(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_336]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATAAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCTCA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(146-237)

Response regulator receiver domain (Response_reg)

(17-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.887

100

0.366