Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   H0504_RS02230 Genome accession   NZ_LR822011
Coordinates   422371..424362 (+) Length   663 a.a.
NCBI ID   WP_002953358.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_23     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 417371..429362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0504_RS02210 (STHERMO_0470) - 417599..418339 (-) 741 WP_002945131.1 amino acid ABC transporter ATP-binding protein -
  H0504_RS02215 (STHERMO_0471) - 418339..420549 (-) 2211 WP_011226350.1 ABC transporter substrate-binding protein/permease -
  H0504_RS09995 - 420748..421684 (+) 937 Protein_403 CPBP family intramembrane glutamic endopeptidase -
  H0504_RS02230 (STHERMO_0476) uvrB 422371..424362 (+) 1992 WP_002953358.1 excinuclease ABC subunit UvrB Machinery gene
  H0504_RS02235 (STHERMO_0477) - 424407..424871 (+) 465 WP_011226345.1 8-oxo-dGTP diphosphatase -
  H0504_RS02240 (STHERMO_0478) - 425084..425914 (+) 831 WP_041828297.1 transporter substrate-binding domain-containing protein -
  H0504_RS02245 (STHERMO_0479) - 425911..426708 (+) 798 WP_011226343.1 transporter substrate-binding domain-containing protein -
  H0504_RS02250 (STHERMO_0480) - 427055..428164 (+) 1110 WP_041828295.1 aminotransferase -
  H0504_RS02255 (STHERMO_0481) - 428257..429051 (+) 795 WP_011226341.1 transporter substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 76099.16 Da        Isoelectric Point: 4.5966

>NTDB_id=1009218 H0504_RS02230 WP_002953358.1 422371..424362(+) (uvrB) [Streptococcus thermophilus isolate STH_CIRM_23]
MIDRKEDNQFHLVSKYEPSGDQPQAIETLVDNIKGGEKAQILKGATGTGKTYTMSQVIQRVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSINDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDKLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDENAFRVEFFGDEIDRICEIESLTGRNL
GEVEHLVLFPATHFMTNEEHMEEAIKNIMEEMEVQVNQFEAEGKLIEAQRIRQRTEYDVEMLREMGYTNGIENYSRHMDG
RKEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKKMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARTEKGERVFVTTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSDGHVIMYADK
ITESMQKAMDETARRREIQMAYNKEHGITPQTIKKEIRDLISITKTNEAEVAEDTVNYSAMNKKERQEAIKKLQKQMHEA
AELLDFELAAQIRDMVLELKSMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=1009218 H0504_RS02230 WP_002953358.1 422371..424362(+) (uvrB) [Streptococcus thermophilus isolate STH_CIRM_23]
ATGATAGATAGAAAAGAAGACAACCAATTTCATTTGGTTTCTAAATACGAACCCTCAGGAGATCAGCCCCAGGCTATCGA
AACCTTGGTTGATAATATCAAAGGTGGGGAGAAGGCTCAAATTTTAAAGGGTGCGACAGGGACAGGTAAGACCTATACCA
TGAGTCAAGTCATCCAACGTGTTAATAAGCCAACTCTGGTTATCGCCCACAATAAGACCTTGGCAGGCCAGCTCTATGGT
GAGTTCAAGGAGTTTTTCCCAGACAATGCTGTAGAGTATTTTGTTTCCTATTATGATTATTACCAGCCAGAGGCTTATGT
GCCTTCATCAGATACCTATATTGAAAAAGATAGCTCTATTAATGATGAAATTGATAAACTCCGTCACTCAGCGACATCAG
CCCTATTGGAACGCAATGATGTAATTGTTGTGGCTTCCGTGTCTTGTATTTACGGTTTGGGTTCGCCAAAAGAATATGCG
GATTCAGCTGTTAGCCTGCGTCCTGGTCAAGAAATTTCTCGGGACAAGTTGCTCAATGACTTGGTTGATATCCAGTTTGA
GCGTAACGATATTGATTTTCAACGCGGAAAATTCCGTGTACGTGGCGATGTGGTTGAAATTTTCCCTGCCAGCCGTGATG
AAAATGCTTTTCGAGTGGAATTTTTCGGTGATGAGATTGACCGTATCTGTGAAATTGAAAGTTTGACAGGACGTAATCTC
GGTGAAGTTGAGCACCTTGTTCTTTTTCCGGCTACTCACTTTATGACCAATGAAGAGCATATGGAAGAAGCTATCAAGAA
TATTATGGAAGAGATGGAGGTTCAGGTTAATCAATTTGAAGCCGAGGGTAAACTCATCGAGGCTCAACGTATTCGTCAAC
GGACAGAATACGATGTCGAAATGCTTCGTGAGATGGGTTACACCAATGGTATCGAAAACTATTCACGTCACATGGATGGT
CGTAAAGAAGGTGAGCCACCGTTTACTCTACTTGATTTCTTCCCAGAAGATTTCCTCATCATGATTGATGAAAGTCACAT
GACCATGGGACAGATTAAAGGAATGTATAACGGAGACCAAGCCCGTAAGAAGATGCTTGTCGATTACGGCTTCCGTTTAC
CATCGGCTCTTGATAACCGTCCCCTTCGTCGTGAAGAATTCGAAAGTCATGTGCATCAGATTGTCTATGTGTCAGCGACA
CCAGGTGACTATGAGATGGAGCAGACTGAGACTGTCGTTGAGCAAATCATCCGTCCGACAGGACTTCTTGATCCAGAAGT
CGAAGTTCGTCCAACTATGGGTCAAATGGATGACCTCCTTGGTGAAATCAATGCCCGTACTGAAAAAGGAGAGCGTGTCT
TTGTAACAACTTTGACTAAGAAGATGGCTGAGGACTTGACCGATTACCTCAAGGAAATGGGAGTCAAGGTCAAATACATG
CACTCTGATATTAAGACTTTGGAGCGTACTGAGATTATCCGTGACTTGCGTTTGGGTGTCTTTGATGTTCTTATTGGGAT
TAACCTTCTTCGTGAGGGTATTGACGTTCCTGAAGTTAGTCTGGTTGCTATTTTGGATGCTGATAAGGAAGGTTTCCTTC
GTAATGAACGTGGGCTTATCCAAACGATTGGACGTGCTGCCCGAAATAGTGATGGGCACGTTATCATGTATGCGGATAAG
ATTACGGAGTCTATGCAGAAAGCTATGGATGAAACTGCTCGTCGTCGTGAAATCCAAATGGCCTATAATAAGGAGCACGG
TATCACTCCGCAAACGATTAAGAAAGAAATTCGTGACCTTATTTCGATTACCAAGACCAATGAAGCAGAAGTGGCAGAGG
ATACTGTGAACTACAGTGCCATGAACAAGAAAGAACGCCAAGAAGCCATCAAGAAACTTCAAAAGCAAATGCACGAAGCG
GCAGAGCTGCTTGATTTTGAATTGGCAGCCCAAATTCGTGATATGGTTCTAGAGCTGAAGAGTATGGATTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(628-660)

Ultra-violet resistance protein B (UvrB)

(556-598)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.219

100

0.852
  uvrB Streptococcus pneumoniae D39

85.219

100

0.852
  uvrB Streptococcus pneumoniae TIGR4

85.068

100

0.851

Multiple sequence alignment