Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   H0507_RS07570 Genome accession   NZ_LR822010
Coordinates   1444020..1446119 (-) Length   699 a.a.
NCBI ID   WP_059257388.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_29     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1439020..1451119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0507_RS07540 (STHERMO_1651) pptB 1439489..1440523 (-) 1035 WP_373867015.1 ABC transporter permease Regulator
  H0507_RS07545 (STHERMO_1652) pptA 1440523..1441254 (-) 732 WP_002951673.1 ABC transporter ATP-binding protein Regulator
  H0507_RS07550 (STHERMO_1653) - 1441319..1441738 (+) 420 WP_011227486.1 HIT family protein -
  H0507_RS07555 (STHERMO_1654) - 1441735..1442043 (+) 309 WP_011227487.1 hypothetical protein -
  H0507_RS09935 (STHERMO_1655) - 1442595..1442765 (-) 171 WP_011226439.1 hypothetical protein -
  H0507_RS07565 (STHERMO_1656) - 1442835..1443470 (-) 636 WP_011226440.1 DUF4230 domain-containing protein -
  H0507_RS10115 - 1443489..1443614 (-) 126 WP_011681534.1 hypothetical protein -
  H0507_RS07570 (STHERMO_1658) clpE 1444020..1446119 (-) 2100 WP_059257388.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  H0507_RS07575 (STHERMO_1659) - 1446834..1447925 (-) 1092 WP_011227489.1 nucleotidyltransferase -
  H0507_RS07580 (STHERMO_1660) - 1447932..1448672 (-) 741 WP_309252055.1 class I SAM-dependent methyltransferase -
  H0507_RS07585 (STHERMO_1661) rsfS 1448997..1449350 (-) 354 WP_011227491.1 ribosome silencing factor -
  H0507_RS07590 (STHERMO_1662) yqeK 1449374..1449964 (-) 591 WP_002951696.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  H0507_RS07595 (STHERMO_1663) - 1449961..1450593 (-) 633 WP_011226445.1 nicotinate-nucleotide adenylyltransferase -
  H0507_RS07600 (STHERMO_1664) yhbY 1450697..1451014 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77182.07 Da        Isoelectric Point: 4.8262

>NTDB_id=1009162 H0507_RS07570 WP_059257388.1 1444020..1446119(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_29]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESIERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=1009162 H0507_RS07570 WP_059257388.1 1444020..1446119(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_29]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCATAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(606-676)

AAA domain (Cdc48 subfamily) (AAA_2)

(439-599)

AAA lid domain (AAA_lid_9)

(255-349)

ATPase family associated with various cellular activities (AAA) (AAA)

(114-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.638

100

0.466
  clpC Lactococcus lactis subsp. cremoris KW2

48.906

91.559

0.448
  clpE Streptococcus pneumoniae D39

48.815

90.558

0.442
  clpE Streptococcus pneumoniae Rx1

48.815

90.558

0.442
  clpE Streptococcus pneumoniae R6

48.815

90.558

0.442
  clpE Streptococcus pneumoniae TIGR4

48.734

90.415

0.441
  clpC Bacillus subtilis subsp. subtilis str. 168

45.975

92.418

0.425
  clpC Streptococcus thermophilus LMD-9

43.26

91.273

0.395
  clpC Streptococcus thermophilus LMG 18311

43.103

91.273

0.393
  clpC Streptococcus pneumoniae TIGR4

43.339

89.127

0.386
  clpC Streptococcus pneumoniae Rx1

43.339

89.127

0.386
  clpC Streptococcus pneumoniae D39

43.339

89.127

0.386
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.274

88.269

0.382
  clpC Streptococcus mutans UA159

42.995

88.841

0.382

Multiple sequence alignment