Detailed information NTG1009159

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: ABK447_RS02740
• Genome accession: NZ_CP157943
• Coordinates: 530066..531229 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. hwrm1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 525066..536229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABK447_RS02720 (ABK447_02715)	-	525452..526648 (+)	1197	WP_094031330.1	glycosyltransferase	-
ABK447_RS02725 (ABK447_02720)	-	526781..527857 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
ABK447_RS02730 (ABK447_02725)	-	527956..529191 (-)	1236	WP_025285355.1	LCP family protein	-
ABK447_RS02735 (ABK447_02730)	-	529196..529843 (-)	648	WP_007407485.1	YigZ family protein	-
ABK447_RS02740 (ABK447_02735)	degS	530066..531229 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
ABK447_RS02745 (ABK447_02740)	degU	531306..531995 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
ABK447_RS02750 (ABK447_02745)	-	532093..532941 (+)	849	WP_094031329.1	DegV family protein	-
ABK447_RS02755 (ABK447_02750)	comFA	533050..534435 (+)	1386	WP_099320008.1	DEAD/DEAH box helicase	Machinery gene
ABK447_RS02760 (ABK447_02755)	-	534493..534777 (+)	285	WP_007407481.1	late competence development ComFB family protein	-
ABK447_RS02765 (ABK447_02760)	comFC	534783..535472 (+)	690	WP_197200179.1	phosphoribosyltransferase family protein	Machinery gene
ABK447_RS02770 (ABK447_02765)	-	535546..535965 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=1009159 ABK447_RS02740 WP_007407484.1 530066..531229(+) (degS) [Bacillus sp. hwrm1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=1009159 ABK447_RS02740 WP_007407484.1 530066..531229(+) (degS) [Bacillus sp. hwrm1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951