Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   ABKA15_RS04205 Genome accession   NZ_CP157941
Coordinates   845814..846656 (+) Length   280 a.a.
NCBI ID   WP_049513260.1    Uniprot ID   A0A7L8W9R9
Organism   Streptococcus sp. KHUD_010     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 840814..851656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS04170 (ABKA15_04165) - 841042..841275 (+) 234 WP_225620251.1 hypothetical protein -
  ABKA15_RS04175 (ABKA15_04170) - 841238..841699 (+) 462 WP_225620252.1 acyl-CoA dehydrogenase family protein -
  ABKA15_RS04180 (ABKA15_04175) - 841703..842620 (+) 918 WP_049513249.1 MBL fold metallo-hydrolase -
  ABKA15_RS04185 (ABKA15_04180) ylqF 842740..843591 (+) 852 WP_049513251.1 ribosome biogenesis GTPase YlqF -
  ABKA15_RS04190 (ABKA15_04185) - 843578..844360 (+) 783 WP_049513254.1 ribonuclease HII -
  ABKA15_RS04195 (ABKA15_04190) - 844357..845184 (+) 828 WP_049513256.1 PRD domain-containing protein -
  ABKA15_RS04200 (ABKA15_04195) - 845174..845731 (+) 558 WP_049513258.1 sugar O-acetyltransferase -
  ABKA15_RS04205 (ABKA15_04200) dprA/cilB/dalA 845814..846656 (+) 843 WP_049513260.1 DNA-processing protein DprA Machinery gene
  ABKA15_RS04210 (ABKA15_04205) topA 846742..848835 (+) 2094 WP_152907028.1 type I DNA topoisomerase -
  ABKA15_RS04215 (ABKA15_04210) - 848899..849396 (+) 498 WP_049513264.1 hypothetical protein -
  ABKA15_RS04220 (ABKA15_04215) trmFO 849570..850904 (+) 1335 WP_049513266.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31011.60 Da        Isoelectric Point: 5.6736

>NTDB_id=1009115 ABKA15_RS04205 WP_049513260.1 845814..846656(+) (dprA/cilB/dalA) [Streptococcus sp. KHUD_010]
MDNFDIYKLKEAGLTNQQVINVLSYAEIQEKELSVKDMAVVSECRNPALFIEKYLQLDGDLLCQEFKKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRTGSQSVQKIVKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGPEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTSGADVLSEFQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1009115 ABKA15_RS04205 WP_049513260.1 845814..846656(+) (dprA/cilB/dalA) [Streptococcus sp. KHUD_010]
ATGGATAATTTTGATATTTATAAATTAAAAGAAGCCGGCTTGACCAACCAACAGGTCATCAATGTTCTTTCGTATGCTGA
GATACAAGAAAAAGAATTATCAGTAAAAGATATGGCAGTTGTGTCGGAATGCCGTAATCCAGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGGTGATTTATTATGTCAAGAATTTAAAAAATTTCCGTCTTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGTGAAATTTACAATCCACCCGTTCTCCTTTTCTACAAAGGAAACTTGGATTTGTTAAAATTACCGAAAGT
AGCTGTTGTGGGAAGTCGCAATAGTAGCCGAACAGGCAGTCAATCTGTTCAAAAAATTGTTAAAGAGCTAAACAATGAGC
TAGTTATCGTAAGCGGCTTAGCGCGCGGAATTGATACGTCAGCTCACATGGCAGCGTTGCAAAATGGCGGTCGAACGATT
GCCGTTATTGGAACCGGTTTAGATGTTTTTTATCCAAGAGCAAATAAAAAACTCCAATCGTATTTGGGAGAACATCACCT
TGTGCTTAGTGAATATGGTCCCGAAGCAGAACCATTGAAATTTCATTTTCCAGAACGGAATCGCATTATTGCAGGTTTGT
GTAGGGGCGTTATTGTCGCTGAAGCCAAAATGCGCTCAGGAAGTCTAATTACTTGTGAGCGCGCAATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
CGTCACATCAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-59)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W9R9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.071

100

0.761
  dprA/cilB/dalA Streptococcus mitis SK321

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.071

100

0.761
  dprA Streptococcus mutans UA159

64.643

100

0.646
  dprA Lactococcus lactis subsp. cremoris KW2

57.857

100

0.579
  dprA Staphylococcus aureus N315

37.943

100

0.382
  dprA Staphylococcus aureus MW2

37.722

100

0.379
  dprA Legionella pneumophila strain ERS1305867

50.739

72.5

0.368

Multiple sequence alignment