Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   H0503_RS00355 Genome accession   NZ_LR822009
Coordinates   62936..63526 (+) Length   196 a.a.
NCBI ID   WP_011680603.1    Uniprot ID   Q03MX8
Organism   Streptococcus thermophilus isolate STH_CIRM_19     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57936..68526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0503_RS10225 - 59066..59521 (-) 456 Protein_45 DUF3021 domain-containing protein -
  H0503_RS00335 (STHERMO_0063) - 59518..59909 (-) 392 Protein_46 LytTR family DNA-binding domain-containing protein -
  H0503_RS00340 (STHERMO_0064) - 60133..60438 (+) 306 WP_002949050.1 hypothetical protein -
  H0503_RS00345 (STHERMO_0065) hexB 60490..62433 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL Machinery gene
  H0503_RS00350 (STHERMO_0066) - 62563..62784 (+) 222 WP_002949052.1 hypothetical protein -
  H0503_RS00355 (STHERMO_0067) ruvA 62936..63526 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA Machinery gene
  H0503_RS00360 (STHERMO_0068) - 63533..64087 (+) 555 WP_011680604.1 DNA-3-methyladenine glycosylase I -
  H0503_RS00365 (STHERMO_0069) cinA 64183..65454 (+) 1272 WP_011680605.1 competence/damage-inducible protein A Machinery gene
  H0503_RS00370 (STHERMO_0070) recA 65490..66659 (+) 1170 WP_179970786.1 recombinase RecA Machinery gene
  H0503_RS00375 (STHERMO_0071) spx 66836..67234 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21683.98 Da        Isoelectric Point: 5.2834

>NTDB_id=1008994 H0503_RS00355 WP_011680603.1 62936..63526(+) (ruvA) [Streptococcus thermophilus isolate STH_CIRM_19]
MYDYIKGTLVKITAKHIVIETNGLGYIVTVANPYSFSDQMNQTIQVYLHQVIRDDAHLLFGFHTEDEKEVFLKLISVSGI
GPTTALAIVAVDDNQGLVAAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFAELPAETTNTTANQTAGNQQLDEAMEALL
ALGYKATELKKVKAFFEDTNETAEQYIKSALKMLMK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1008994 H0503_RS00355 WP_011680603.1 62936..63526(+) (ruvA) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGTATGATTATATCAAGGGCACCCTAGTAAAAATCACAGCCAAACACATTGTCATAGAAACAAATGGTCTAGGATATAT
TGTCACTGTGGCTAATCCCTACAGCTTTTCTGATCAAATGAATCAGACTATCCAAGTGTATCTTCATCAAGTTATTAGAG
ATGATGCCCACCTACTTTTTGGTTTTCATACTGAAGATGAGAAAGAAGTTTTTCTTAAGTTGATTTCTGTTTCTGGGATA
GGTCCGACGACTGCTCTAGCCATAGTGGCTGTGGATGATAATCAGGGACTTGTTGCTGCTATTGATAATAGTGACATCAA
ATACCTGATGAAATTTCCAAAGATTGGTAAAAAGACTGCTCAACAAATGGTTCTTGATCTGGCAGGAAAATTTGCAGAGT
TACCAGCAGAAACGACCAATACTACGGCAAATCAGACTGCAGGAAATCAACAGTTGGATGAAGCTATGGAAGCTTTGCTT
GCTCTTGGGTACAAAGCCACAGAGCTTAAGAAAGTGAAAGCCTTCTTTGAGGATACCAATGAAACGGCAGAGCAATATAT
TAAGTCCGCTCTTAAAATGTTGATGAAGTGA

Domains

Predicted by InterProScan.

RuvA, C-terminal domain (RuvA_C)

(151-195)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03MX8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.5

100

0.679
  ruvA Streptococcus pneumoniae R6

66.5

100

0.679
  ruvA Streptococcus pneumoniae D39

66.5

100

0.679
  ruvA Bacillus subtilis subsp. subtilis str. 168

42.647

100

0.444