Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL05_RS04335 Genome accession   NZ_LR594044
Coordinates   879470..880798 (+) Length   442 a.a.
NCBI ID   WP_020916819.1    Uniprot ID   A0AB33ALY3
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 874470..885798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS04320 (NCTC8796_00924) phoU 875211..875864 (+) 654 WP_020916822.1 phosphate signaling complex protein PhoU -
  FGL05_RS04325 (NCTC8796_00925) - 876095..878638 (+) 2544 WP_111712817.1 M1 family metallopeptidase -
  FGL05_RS04330 (NCTC8796_00926) ciaR 878806..879480 (+) 675 WP_020916820.1 response regulator transcription factor Regulator
  FGL05_RS04335 (NCTC8796_00927) ciaH 879470..880798 (+) 1329 WP_020916819.1 HAMP domain-containing sensor histidine kinase Regulator
  FGL05_RS04340 - 880867..882215 (+) 1349 WP_111712816.1 IS3 family transposase -
  FGL05_RS04345 (NCTC8796_00930) rpsT 882317..882568 (-) 252 WP_004231769.1 30S ribosomal protein S20 -
  FGL05_RS04350 (NCTC8796_00931) coaA 882644..883564 (-) 921 WP_020916817.1 type I pantothenate kinase -
  FGL05_RS04355 (NCTC8796_00932) - 883696..884289 (+) 594 WP_061407804.1 class I SAM-dependent methyltransferase -
  FGL05_RS04360 (NCTC8796_00933) deoC 884792..885457 (+) 666 WP_111712815.1 deoxyribose-phosphate aldolase -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 50230.16 Da        Isoelectric Point: 6.5190

>NTDB_id=1005559 FGL05_RS04335 WP_020916819.1 879470..880798(+) (ciaH) [Streptococcus lutetiensis strain NCTC8796]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSIQSNNSFSN
SGKSKPSSNVASLSNVSVLLYDTNGKIVNAIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVSHNF
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRYNFGK

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=1005559 FGL05_RS04335 WP_020916819.1 879470..880798(+) (ciaH) [Streptococcus lutetiensis strain NCTC8796]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACTACTTTAAAAAATG
CAGCTGACAATGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCATACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAAGTAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTACTGTACGATACAAATGGGAAAAT
CGTAAATGCAATTGATGCGTTTGTCCAGTTCGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ATGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACAGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCTTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGACCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAATCTTGCTAGGCGAGATGATGGATTGAAGGTTGAATTAGAAGAAATCCAAC
CTTCAATATTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAACGGTAAAACTTTTGTTTCTCATAATTTT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGATGACGGTTTTATTGAATTTACGGTTAAAACAACAGAACGCCAGACTATTCTAACCGTTGCTGATAATGGACCGG
GTATTAGTGACGCCGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGGCTTGGGCTATCTTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGATATTCAAGTTAAGGATAATCATCCAAA
AGGAACCATATTTGAAGTTCGTTTTAACCGATATAATTTTGGTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33ALY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.77

98.416

0.588
  ciaH Streptococcus pneumoniae Rx1

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae D39

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae R6

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae TIGR4

52.403

98.869

0.518