Detailed information NTG1005201

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FGK97_RS09230
• Genome accession: NZ_LR594037
• Coordinates: 1822007..1824568 (-)
• Length: 853 a.a.
• NCBI ID: WP_057489838.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain NCTC11064
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1817007..1829568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK97_RS09205 (NCTC11064_01893)	ruvA	1817088..1817678 (-)	591	WP_021002202.1	Holliday junction branch migration protein RuvA	Machinery gene
FGK97_RS09210 (NCTC11064_01894)	-	1817840..1818349 (+)	510	WP_003026648.1	helix-turn-helix domain-containing protein	-
FGK97_RS09215 (NCTC11064_01895)	hexB	1818732..1820678 (-)	1947	WP_138099533.1	DNA mismatch repair endonuclease MutL	Machinery gene
FGK97_RS09220 (NCTC11064_01896)	brsR	1820923..1821363 (+)	441	WP_138099534.1	LytTR family DNA-binding domain-containing protein	Regulator
FGK97_RS09225 (NCTC11064_01897)	-	1821360..1821818 (+)	459	WP_021002204.1	DUF3021 domain-containing protein	-
FGK97_RS09230 (NCTC11064_01898)	hexA	1822007..1824568 (-)	2562	WP_057489838.1	DNA mismatch repair protein MutS	Machinery gene
FGK97_RS09235 (NCTC11064_01899)	argR	1824731..1825171 (-)	441	WP_003027809.1	arginine repressor	-
FGK97_RS09240 (NCTC11064_01900)	argS	1825275..1826963 (+)	1689	WP_021002206.1	arginine--tRNA ligase	-
FGK97_RS09245 (NCTC11064_01901)	nrdI	1827018..1827473 (-)	456	WP_021002207.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
FGK97_RS09250 (NCTC11064_01902)	-	1827549..1828058 (-)	510	WP_003026664.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96049.80 Da
• Isoelectric Point: 5.0000

>NTDB_id=1005201 FGK97_RS09230 WP_057489838.1 1822007..1824568(-) (hexA) [Streptococcus anginosus strain NCTC11064]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNM
VCGEIRNLRAREVVLGYELSEMERQVLEIQMNLLLSQVETTFDDVQLLGKDLSPLERQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDTLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELANLIQLAISP
DAPNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNQTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQANEKSSFGISNTL
PADAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=1005201 FGK97_RS09230 WP_057489838.1 1822007..1824568(-) (hexA) [Streptococcus anginosus strain NCTC11064]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGCTATT
TCGTATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAATCCAATCCCGATGGCAGGAGTTCCCTACCATTCGGTGCAACAGTATATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGGCTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATG
GTCTGTGGAGAAATCCGAAACTTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGTCTGAAATGGAGCGCCAAGTATT
GGAGATTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCGCCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGATTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGAGACTAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAACGCAGTGACTTATCAGACACTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCGAAAGATCTATTACAACTTGCTGCGACATTGAGTCATGTACCACAAATTAAGGGAATCTTAAAAGGAATTGACA
GCCCAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAATTGGCAAACTTGATTCAGTTGGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGACAAGTATCGAGTGGTCAT
GCGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACCAATTCTCAGCTTGAACATGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTTTGAAAAATTCGGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGTGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
AAACTCTGGCAACGGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCAGAAAAGCAACATTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCCGAAAGTGCCCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGGTGGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCTACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCAGACAGGAGCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTTTTGGCATCTCTAATACATTG
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (255-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.788	100	0.768
mutS	Pseudomonas stutzeri strain ATCC 17587	36.121	100	0.365