Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FGK97_RS09215 Genome accession   NZ_LR594037
Coordinates   1818732..1820678 (-) Length   648 a.a.
NCBI ID   WP_138099533.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC11064     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1813732..1825678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK97_RS09185 (NCTC11064_01890) cinA 1814104..1815375 (-) 1272 WP_021002200.1 competence/damage-inducible protein A Machinery gene
  FGK97_RS09195 - 1815976..1816396 (+) 421 Protein_1771 EamA family transporter -
  FGK97_RS09200 (NCTC11064_01892) - 1816499..1817077 (-) 579 WP_021002201.1 DNA-3-methyladenine glycosylase I -
  FGK97_RS09205 (NCTC11064_01893) ruvA 1817088..1817678 (-) 591 WP_021002202.1 Holliday junction branch migration protein RuvA Machinery gene
  FGK97_RS09210 (NCTC11064_01894) - 1817840..1818349 (+) 510 WP_003026648.1 helix-turn-helix domain-containing protein -
  FGK97_RS09215 (NCTC11064_01895) hexB 1818732..1820678 (-) 1947 WP_138099533.1 DNA mismatch repair endonuclease MutL Machinery gene
  FGK97_RS09220 (NCTC11064_01896) brsR 1820923..1821363 (+) 441 WP_138099534.1 LytTR family DNA-binding domain-containing protein Regulator
  FGK97_RS09225 (NCTC11064_01897) - 1821360..1821818 (+) 459 WP_021002204.1 DUF3021 domain-containing protein -
  FGK97_RS09230 (NCTC11064_01898) hexA 1822007..1824568 (-) 2562 WP_057489838.1 DNA mismatch repair protein MutS Machinery gene
  FGK97_RS09235 (NCTC11064_01899) argR 1824731..1825171 (-) 441 WP_003027809.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73131.33 Da        Isoelectric Point: 5.1688

>NTDB_id=1005199 FGK97_RS09215 WP_138099533.1 1818732..1820678(-) (hexB) [Streptococcus anginosus strain NCTC11064]
MSKIIELPENLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLRSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATSSGAHGTLLIAQGGEVETLEPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLVNDGKEMARTAGTGNLRQAIAGIYGLTTAKKMIEILASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMVLISQ
AIAASLKEQDLIPDALENLAKSTINRAIKPEQTSLPLKENRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKAASVKFAERQSPSYNQLDHPELDQASLERALDKLNGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMTLLEEVGVFLEEYGTNQFILREHPIWLKEEEIESGIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMGKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=1005199 FGK97_RS09215 WP_138099533.1 1818732..1820678(-) (hexB) [Streptococcus anginosus strain NCTC11064]
ATGTCAAAAATTATTGAACTACCAGAAAATCTTGCTAATCAGATTGCAGCAGGTGAGGTTATTGAGCGACCTAGCAGCGT
TGTCAAGGAGTTAATAGAAAATTCTATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCGGGACTCAGGA
GCATTCAAGTCATTGATAATGGTGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTACGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTTTTTCGAATTCGGACATTGGGCTTTCGGGGCGAGGCACTTCCATCCATTGCCTCTGTTTC
ACGTTTGACGATTGAAACTGCGACAAGTAGTGGTGCACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAGTTGAGACTT
TAGAGCCAAGTAGCTGTCCTAGGGGCACCAAAATCAAAGTGGAAGACCTTTTTTTCAACACGCCTGCTCGCTTGAAATAT
ATGAAAAGTCAACAAGCGGAACTATCTCACATTGTAGATGTGATTAACCGTTTGAGCTTGGCTCATCCGGAGGTCGCTTT
CACTCTTGTTAATGACGGTAAAGAGATGGCACGGACAGCAGGAACAGGAAATCTGCGTCAAGCAATTGCTGGCATTTATG
GACTGACAACAGCCAAAAAAATGATTGAAATTTTAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATCCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTTCCGATTGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTCAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAGGAGCGAGAGCTCATGGTCTTGATATCGCAA
GCTATTGCTGCAAGTTTGAAAGAGCAAGATTTGATTCCGGACGCATTAGAGAATTTAGCCAAATCAACCATTAACCGAGC
AATTAAGCCTGAACAGACCAGCCTCCCTCTCAAAGAGAACCGACTTTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCCCGATTAGACCAACAATCTGCTGATACAGATGAACTC
AATTCAAAAGCTGCTTCTGTCAAATTTGCAGAAAGGCAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGCTAAATGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGCCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TACGAATATTACCGTGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATCTTTGAATTTCC
AGCTGATGATATGTTGCGTCTGAAACAACGAATGACTCTTTTAGAAGAAGTCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGGTATTTATGAGATGTGCGATATG
CTGCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTGGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTAGATGACTATTCAGCGCGTGATTTGATTTTTCAGTTATCACAATGCGACAATCCCTACAACTGCC
CTCACGGTCGTCCCGTTTTGGTCAACTTCACCAAATCTGATATGGGAAAAATGTTCCGTCGGATTCAGGAAAACCATACT
AGCCTGAGAGAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

76.888

100

0.77

Multiple sequence alignment