Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FGL04_RS10335 Genome accession   NZ_LR594035
Coordinates   2001104..2003071 (-) Length   655 a.a.
NCBI ID   WP_138069094.1    Uniprot ID   -
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1996104..2008071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS10310 (NCTC5385_02231) recA 1996107..1997249 (-) 1143 WP_138069089.1 recombinase RecA Machinery gene
  FGL04_RS10315 (NCTC5385_02232) cinA 1997339..1998598 (-) 1260 WP_138069090.1 competence/damage-inducible protein A Machinery gene
  FGL04_RS10320 (NCTC5385_02233) - 1998714..1999268 (-) 555 WP_138069091.1 DNA-3-methyladenine glycosylase I -
  FGL04_RS10325 (NCTC5385_02234) ruvA 1999275..1999868 (-) 594 WP_138069092.1 Holliday junction branch migration protein RuvA Machinery gene
  FGL04_RS10330 (NCTC5385_02235) - 1999870..2001093 (-) 1224 WP_138069093.1 MFS transporter -
  FGL04_RS10335 (NCTC5385_02236) hexB 2001104..2003071 (-) 1968 WP_138069094.1 DNA mismatch repair endonuclease MutL Machinery gene
  FGL04_RS10340 (NCTC5385_02237) - 2003579..2006545 (+) 2967 WP_225247836.1 serum opacification factor -
  FGL04_RS10345 (NCTC5385_02238) - 2007539..2007751 (+) 213 WP_138069096.1 YSIRK-type signal peptide-containing protein -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 73843.34 Da        Isoelectric Point: 5.4494

>NTDB_id=1005084 FGL04_RS10335 WP_138069094.1 2001104..2003071(-) (hexB) [Streptococcus pseudoporcinus strain NCTC5385]
MTKIIELPEILANQIAAGEVIERPASVVKELVENGIDAKSSQITIDIEESGLKSITITDNGEGMSEQDLPMSILRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISELTIASATEESEHGSQLFVRGGKIEGQEAISMPVGTRIRVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLGHPGIAFTLISDGREMTRTSGSGQLKQAIAGIYGLKTAKKMIEIANADLDFDVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AIAESLKAQDLIPDALENLAKSSTRSLPKVEQTRLTLQTRKLYYDPHENDFFVEKKDVSEAQTPIYSDSFDLDRPVKLAE
EASVELSSPAVKHASRPDTEELVGDHSDLTFKNKHKLEQVVERLENEEASTFPELDYFGQMHGTYLFAQGVDGLFIIDQH
AAQERVKYEYYREKIGEVDSSLQQLLVPYLFEFSGSDFLTLQEKMSLLNDVGIYLEPYGHHTFILREHPIWMKESEIEAG
VYEMCDMLLLTQEVSIKTYRAELAIMMSCKKSIKANHTLDDYSARQLLLQLAQCKNPYNCPHGRPVLIHFSKSDMEKMFR
RIQENHTSLRDLGKY

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=1005084 FGL04_RS10335 WP_138069094.1 2001104..2003071(-) (hexB) [Streptococcus pseudoporcinus strain NCTC5385]
ATGACTAAAATTATTGAATTACCAGAAATTCTCGCCAATCAGATTGCAGCTGGGGAAGTTATTGAGCGTCCAGCAAGTGT
CGTTAAAGAATTGGTAGAGAATGGCATTGATGCAAAAAGTAGTCAGATTACTATTGATATTGAAGAATCAGGCTTAAAGT
CTATAACCATAACCGATAATGGTGAAGGCATGTCGGAGCAAGATTTGCCCATGAGTATCCTTCGTCATGCAACCAGTAAG
ATAAAAAATCAGGGTGATCTTTTTCGTATTAGAACACTTGGTTTTAGAGGAGAGGCATTACCTTCGATTGCTTCAATTAG
TGAGTTGACCATTGCTTCTGCTACAGAAGAGTCTGAGCATGGTAGCCAACTCTTTGTGCGTGGTGGCAAGATTGAGGGGC
AAGAAGCAATTTCGATGCCTGTTGGAACTCGGATAAGGGTTGAAAATCTTTTTTATAATACGCCAGCACGTCTAAAATAC
ATGAAGAGTCTCCAATCAGAATTGGCTCATATTGTCGATGTGGTCAATCGTTTAAGTTTAGGACACCCTGGAATAGCCTT
CACTCTCATATCTGATGGGCGAGAAATGACTAGAACATCTGGAAGTGGTCAGTTGAAACAAGCCATTGCAGGTATTTACG
GTCTAAAAACTGCAAAAAAAATGATCGAAATAGCTAATGCAGACTTAGACTTTGACGTCAGTGGTTATGTTAGTCTGCCA
GAACTAACTCGGGCAAACCGAAATTATATTACCATTTTAATTAATGGTCGCTATATCAAAAATTTTTTACTCAATCGTGC
TATTTTAGATGGCTATGGTTCCAAATTAATGGTGGGGCGTTTCCCGATTGTGGTTATTGATATTCAGATTGACCCTTACT
TAGCGGATGTCAACGTTCACCCGACAAAGCAAGAAGTTCGTATCTCTAAGGAAAGAGAGTTAATGGCTTTGATTAGCACT
GCTATTGCAGAAAGTTTAAAAGCCCAAGATTTAATTCCTGATGCCTTGGAAAATTTAGCAAAATCAAGCACTCGTTCTTT
GCCAAAAGTAGAGCAGACGCGTTTGACTTTACAGACTCGTAAACTTTATTATGATCCCCATGAAAATGATTTTTTTGTCG
AAAAGAAGGATGTTAGCGAAGCTCAGACTCCGATTTATTCTGACAGCTTTGATCTTGACAGACCTGTCAAGCTAGCAGAA
GAGGCGTCAGTGGAATTATCATCGCCTGCTGTTAAGCATGCTAGTCGCCCAGATACTGAAGAGCTAGTAGGTGATCATTC
TGACTTAACTTTTAAAAATAAGCATAAGTTGGAACAAGTGGTGGAACGTTTGGAAAACGAAGAAGCGTCGACATTTCCCG
AGTTAGACTATTTTGGACAAATGCACGGGACTTATCTCTTTGCTCAAGGGGTTGATGGGCTTTTCATTATTGATCAGCAT
GCGGCTCAGGAGCGGGTTAAGTATGAATATTACCGTGAGAAAATTGGGGAAGTTGACAGCAGTTTACAGCAACTGCTTGT
TCCCTATCTTTTTGAATTTTCAGGATCTGATTTTTTGACTTTACAGGAAAAAATGTCTCTTTTAAATGATGTGGGAATCT
ATCTGGAGCCGTACGGGCATCATACTTTTATTTTGCGGGAACACCCTATTTGGATGAAAGAAAGTGAGATTGAAGCTGGC
GTTTATGAGATGTGTGATATGTTGCTTTTGACTCAGGAAGTTTCCATTAAGACCTACAGGGCTGAGTTGGCTATCATGAT
GAGCTGTAAAAAATCAATCAAAGCTAACCATACCTTGGATGATTATTCTGCAAGACAATTGTTGTTACAGTTGGCACAGT
GTAAAAATCCTTATAACTGTCCACATGGGCGTCCAGTCTTGATTCATTTTAGTAAATCAGATATGGAAAAAATGTTCCGC
CGTATTCAAGAAAATCATACTAGTTTGAGAGATTTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(457-599)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.293

100

0.684