Detailed information NTG1004430

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: E0F34_RS00975
• Genome accession: NZ_LR536843
• Coordinates: 175660..176253 (+)
• Length: 197 a.a.
• NCBI ID: WP_000271487.1
• Uniprot ID: Q97SY4
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 170660..181253

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS00955 (SAMEA104035599_00177)	ribE	171842..172309 (-)	468	WP_001099505.1	6,7-dimethyl-8-ribityllumazine synthase	-
E0F34_RS00960 (SAMEA104035599_00178)	-	172310..173515 (-)	1206	WP_050269927.1	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	-
E0F34_RS00965 (SAMEA104035599_00179)	ribE	173535..174170 (-)	636	WP_000493842.1	riboflavin synthase	-
E0F34_RS00970 (SAMEA104035599_00180)	ribD	174155..175255 (-)	1101	WP_001284096.1	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	-
E0F34_RS00975 (SAMEA104035599_00182)	ruvA	175660..176253 (+)	594	WP_000271487.1	Holliday junction branch migration protein RuvA	Machinery gene
E0F34_RS00980 (SAMEA104035599_00183)	-	176263..176826 (+)	564	WP_000166605.1	DNA-3-methyladenine glycosylase I	-
E0F34_RS00985 (SAMEA104035599_00184)	-	176823..177500 (+)	678	WP_000987429.1	CPBP family intramembrane glutamic endopeptidase	-
E0F34_RS00990 (SAMEA104035599_00185)	-	177655..178686 (-)	1032	WP_000255092.1	S66 peptidase family protein	-
E0F34_RS00995 (SAMEA104035599_00186)	-	178941..179624 (-)	684	WP_000078022.1	DUF1129 domain-containing protein	-
E0F34_RS01000 (SAMEA104035599_00187)	-	179636..180580 (-)	945	WP_000815629.1	magnesium transporter CorA family protein	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21606.10 Da
• Isoelectric Point: 6.7338

>NTDB_id=1004430 E0F34_RS00975 WP_000271487.1 175660..176253(+) (ruvA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEAQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGI
GPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK

Nucleotide

• Length: 594 bp

>NTDB_id=1004430 E0F34_RS00975 WP_000271487.1 175660..176253(+) (ruvA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGTACGCATATTTAAAAGGAATCATTACCAAAATTACTGCCAAATACATTGTTCTTGAAACCAATGGTATTGGTTATAT
CCTGCATGTGGCCAATCCTTATGCCTATTCAGGTCAGGTTAATCAGGAGGCTCAGATTTATGTGCATCAGGTTGTGCGTG
AGGATGCCCATTTGCTTTATGGATTTCGCTCAGAGGATGAGAAAAAGCTCTTTCTTAGTCTGATTTCGGTCTCTGGGATT
GGTCCTGTATCAGCTCTTGCTATTATCGCTGCTGATGACAATGCTGGCTTGGTTCAAGCCATTGAAACCAAGAACATCAC
CTACTTGACCAAGTTCCCTAAAATTGGCAAGAAAACAGCCCAGCAGATGGTGCTGGACTTGGAAGGCAAGGTAGTAGTTG
CAGGAGATGACCTTCCTGCCAAGGTCGCAGTGCAAGCAAGTGCTGAAAACCAAGAATTGGAAGAAGCTATGGAAGCCATG
TTGGCTCTGGGCTACAAGGCAACAGAGCTCAAGAAAATCAAGAAATTCTTTGAAGGAACGACAGATACAGCTGAGAACTA
TATCAAGTCGGCCCTTAAAATGTTGGTCAAATAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (71-127)

• RuvA N terminal domain (RuvA_N) (1-61)

3D structure

• AlphaFold DB: Q97SY4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae TIGR4	100	100	1
ruvA	Streptococcus pneumoniae R6	99.492	100	0.995
ruvA	Streptococcus pneumoniae D39	99.492	100	0.995
ruvA	Bacillus subtilis subsp. subtilis str. 168	39.806	100	0.416