Detailed information NTG1004015

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: E0F31_RS09715
• Genome accession: NZ_LR216064
• Coordinates: 1810328..1811227 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904858.1
• Uniprot ID: A0A0H2URY1
• Organism: Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1805328..1816227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F31_RS09700 (SAMEA3714520_01826)	rsmA	1805977..1806849 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
E0F31_RS11940	-	1807100..1807393 (-)	294	Protein_1837	hypothetical protein	-
E0F31_RS09705 (SAMEA3714520_01828)	-	1807386..1808027 (-)	642	WP_054363289.1	ABC transporter ATP-binding protein	-
E0F31_RS09710 (SAMEA3714520_01829)	-	1808029..1810059 (-)	2031	WP_000825259.1	bacteriocin-associated integral membrane family protein	-
E0F31_RS09715 (SAMEA3714520_01830)	comR	1810328..1811227 (-)	900	WP_000904858.1	helix-turn-helix transcriptional regulator	Regulator
E0F31_RS09720 (SAMEA3714520_01831)	rnmV	1811299..1811859 (-)	561	WP_000660004.1	ribonuclease M5	-
E0F31_RS09725 (SAMEA3714520_01832)	-	1811859..1812632 (-)	774	WP_050206482.1	TatD family hydrolase	-
E0F31_RS09735 (SAMEA3714520_01833)	-	1812937..1813908 (-)	972	Protein_1843	DUF1542 domain-containing protein	-
E0F31_RS09740 (SAMEA3714520_01834)	rpmH	1814114..1814248 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
E0F31_RS09745 (SAMEA3714520_01835)	-	1814393..1815607 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
E0F31_RS09750 (SAMEA3714520_01836)	-	1815763..1816057 (-)	295	Protein_1846	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.11 Da
• Isoelectric Point: 4.7119

>NTDB_id=1004015 E0F31_RS09715 WP_000904858.1 1810328..1811227(-) (comR) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=1004015 E0F31_RS09715 WP_000904858.1 1810328..1811227(-) (comR) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

3D structure

• AlphaFold DB: A0A0H2URY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361