Detailed information NTG1003598

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: EL323_RS10305
• Genome accession: NZ_LR134526
• Coordinates: 1759538..1760122 (+)
• Length: 194 a.a.
• NCBI ID: WP_002234505.1
• Uniprot ID: A1KRU4
• Organism: Neisseria meningitidis strain NCTC10026
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1754538..1765122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL323_RS15045 (NCTC10026_01694)	-	1754739..1755365 (-)	627	WP_226876307.1	hypothetical protein	-
EL323_RS10270 (NCTC10026_01695)	-	1755441..1756229 (-)	789	WP_080541868.1	methyltransferase	-
EL323_RS10275 (NCTC10026_01696)	bioH	1756231..1756974 (-)	744	WP_080541869.1	pimeloyl-ACP methyl ester esterase BioH	-
EL323_RS10280 (NCTC10026_01697)	-	1756973..1757698 (+)	726	WP_025462422.1	ComF family protein	-
EL323_RS10285 (NCTC10026_01698)	trmL	1757763..1758227 (+)	465	WP_002215661.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
EL323_RS10290	-	1758238..1758360 (+)	123	WP_009346050.1	hypothetical protein	-
EL323_RS10295 (NCTC10026_01699)	-	1758357..1759076 (+)	720	WP_002231625.1	septal ring lytic transglycosylase RlpA family protein	-
EL323_RS10300 (NCTC10026_01700)	-	1759130..1759456 (+)	327	WP_002218661.1	PepSY domain-containing protein	-
EL323_RS10305 (NCTC10026_01701)	ruvA	1759538..1760122 (+)	585	WP_002234505.1	Holliday junction branch migration protein RuvA	Machinery gene
EL323_RS10310 (NCTC10026_01702)	-	1760122..1760259 (+)	138	WP_002215654.1	hypothetical protein	-
EL323_RS10315 (NCTC10026_01703)	-	1760285..1762141 (+)	1857	WP_080542388.1	ABC transporter ATP-binding protein	-
EL323_RS10320 (NCTC10026_01704)	rsgA	1762146..1763069 (+)	924	WP_080541870.1	ribosome small subunit-dependent GTPase A	-
EL323_RS10330 (NCTC10026_01705)	-	1763316..1763540 (+)	225	WP_080541871.1	exodeoxyribonuclease VII small subunit	-
EL323_RS10335 (NCTC10026_01706)	-	1763524..1764420 (+)	897	WP_002251008.1	polyprenyl synthetase family protein	-
EL323_RS10340 (NCTC10026_01707)	-	1764529..1764828 (-)	300	WP_002215645.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20628.88 Da
• Isoelectric Point: 5.8480

>NTDB_id=1003598 EL323_RS10305 WP_002234505.1 1759538..1760122(+) (ruvA) [Neisseria meningitidis strain NCTC10026]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVSG
IGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHAVTDGLFAAAPAADETEDIVGTLLA
LGYSEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=1003598 EL323_RS10305 WP_002234505.1 1759538..1760122(+) (ruvA) [Neisseria meningitidis strain NCTC10026]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAAACATTCCGCCAACTGATTAAGGTCAGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCAGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCCCCGGGAATCGGCAAAAAAACCGCCGAACGCATGGTTTTGGAACTGCGCGGCAAGCTGGTCG
CGCATGCGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCGGCACGCTCCTCGCC
CTCGGTTACAGCGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAAGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• RuvA, C-terminal domain (RuvA_C) (150-192)

• RuvA N terminal domain (RuvA_N) (1-62)

• Helix-hairpin-helix domain (HHH_5) (72-129)

3D structure

• AlphaFold DB: A1KRU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38.5	100	0.397
ruvA	Streptococcus pneumoniae D39	38.5	100	0.397
ruvA	Streptococcus pneumoniae TIGR4	38	100	0.392
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.437	100	0.376