Detailed information    

insolico Bioinformatically predicted

Overview


Name   comE   Type   Machinery gene
Locus tag   ABEF80_RS01910 Genome accession   NZ_CP156772
Coordinates   397077..397580 (+) Length   167 a.a.
NCBI ID   WP_347456734.1    Uniprot ID   -
Organism   Acinetobacter thermotolerans strain ANC 7970     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 379187..419247 397077..397580 within 0


Gene organization within MGE regions


Location: 379187..419247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABEF80_RS01840 (ABEF80_01840) - 379187..382810 (+) 3624 WP_347455484.1 fused MFS/spermidine synthase -
  ABEF80_RS01845 (ABEF80_01845) - 382926..384560 (+) 1635 WP_347455485.1 Wzy polymerase domain-containing protein -
  ABEF80_RS01850 (ABEF80_01850) bfr 384615..385079 (-) 465 WP_347456728.1 bacterioferritin -
  ABEF80_RS01855 (ABEF80_01855) - 385319..385513 (-) 195 WP_347453509.1 bacterioferritin-associated ferredoxin -
  ABEF80_RS01860 (ABEF80_01860) - 385702..386085 (-) 384 WP_347453510.1 RidA family protein -
  ABEF80_RS01865 (ABEF80_01865) - 386161..388263 (-) 2103 WP_347456729.1 HD domain-containing protein -
  ABEF80_RS01870 (ABEF80_01870) rpoZ 388476..388757 (-) 282 WP_034587719.1 DNA-directed RNA polymerase subunit omega -
  ABEF80_RS01875 (ABEF80_01875) gmk 388832..389455 (-) 624 WP_034587720.1 guanylate kinase -
  ABEF80_RS01880 (ABEF80_01880) ispH 389590..390540 (+) 951 WP_347456730.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  ABEF80_RS01885 (ABEF80_01885) - 390704..391252 (+) 549 WP_347456731.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  ABEF80_RS01890 (ABEF80_01890) pilV 391249..391770 (+) 522 WP_218951679.1 type IV pilus modification protein PilV -
  ABEF80_RS01895 (ABEF80_01895) - 391767..392681 (+) 915 WP_180182064.1 PilW family protein -
  ABEF80_RS01900 (ABEF80_01900) - 392686..393426 (+) 741 WP_347456732.1 hypothetical protein -
  ABEF80_RS01905 (ABEF80_01905) - 393442..397077 (+) 3636 WP_347456733.1 hypothetical protein -
  ABEF80_RS01910 (ABEF80_01910) comE 397077..397580 (+) 504 WP_347456734.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  ABEF80_RS01915 (ABEF80_01915) - 397574..398005 (+) 432 WP_347456735.1 type IV pilin protein -
  ABEF80_RS01920 (ABEF80_01920) rpsP 398126..398383 (+) 258 WP_034587736.1 30S ribosomal protein S16 -
  ABEF80_RS01925 (ABEF80_01925) rimM 398413..398961 (+) 549 WP_347456736.1 ribosome maturation factor RimM -
  ABEF80_RS01930 (ABEF80_01930) trmD 399003..399752 (+) 750 WP_347456186.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  ABEF80_RS01935 (ABEF80_01935) rplS 399929..400300 (+) 372 WP_004787066.1 50S ribosomal protein L19 -
  ABEF80_RS01940 (ABEF80_01940) - 400362..401345 (-) 984 WP_034587797.1 triacylglycerol lipase -
  ABEF80_RS01945 (ABEF80_01945) - 401881..402912 (-) 1032 WP_347454469.1 lipase secretion chaperone -
  ABEF80_RS01950 (ABEF80_01950) truB 403068..403973 (+) 906 WP_347453523.1 tRNA pseudouridine(55) synthase TruB -
  ABEF80_RS01955 (ABEF80_01955) - 403996..404763 (+) 768 WP_347455492.1 TSUP family transporter -
  ABEF80_RS01960 (ABEF80_01960) - 404892..405354 (+) 463 Protein_372 hemerythrin domain-containing protein -
  ABEF80_RS01965 (ABEF80_01965) - 405409..405822 (-) 414 WP_347455493.1 hypothetical protein -
  ABEF80_RS01970 (ABEF80_01970) - 405894..406772 (-) 879 WP_347453527.1 EamA family transporter -
  ABEF80_RS01975 (ABEF80_01975) - 406956..407831 (-) 876 WP_000102417.1 IS982-like element ISAba825 family transposase -
  ABEF80_RS01980 (ABEF80_01980) - 408076..409227 (+) 1152 WP_347456737.1 hypothetical protein -
  ABEF80_RS01985 (ABEF80_01985) - 409350..409523 (+) 174 WP_347454463.1 hypothetical protein -
  ABEF80_RS01990 (ABEF80_01990) - 409739..410797 (-) 1059 WP_034586922.1 RNA-guided endonuclease TnpB family protein -
  ABEF80_RS01995 (ABEF80_01995) tnpA 410818..411231 (+) 414 WP_075167884.1 IS200/IS605 family transposase -
  ABEF80_RS02000 (ABEF80_02000) serA 411378..412610 (-) 1233 WP_034587753.1 phosphoglycerate dehydrogenase -
  ABEF80_RS02005 (ABEF80_02005) - 412965..414374 (+) 1410 WP_347454120.1 FAD-binding oxidoreductase -
  ABEF80_RS02010 (ABEF80_02010) - 414525..414899 (+) 375 WP_347454460.1 hypothetical protein -
  ABEF80_RS02015 (ABEF80_02015) - 415071..416300 (+) 1230 WP_347454121.1 MFS transporter -
  ABEF80_RS02020 (ABEF80_02020) - 416639..417868 (+) 1230 WP_347456840.1 transposase -
  ABEF80_RS02025 (ABEF80_02025) - 418018..419247 (+) 1230 WP_347455790.1 transposase -

Sequence


Protein


Download         Length: 167 a.a.        Molecular weight: 18496.48 Da        Isoelectric Point: 9.4464

>NTDB_id=1002593 ABEF80_RS01910 WP_347456734.1 397077..397580(+) (comE) [Acinetobacter thermotolerans strain ANC 7970]
MHKSNHGFTLIELMVVVVIVALLAAIALPSYQQYIRKKDMALAQQEMLKLADQLERHKAKNFSYKKFDPKYLYSGITTPL
NVVYVPGGISTAKSKYKIEIKDISNSTEVDLLTSSLGKAWSMKASPINSSDALLYTFLITSHGIKCKAKEAENVSFTACS
GQGAEDW

Nucleotide


Download         Length: 504 bp        

>NTDB_id=1002593 ABEF80_RS01910 WP_347456734.1 397077..397580(+) (comE) [Acinetobacter thermotolerans strain ANC 7970]
ATGCACAAATCTAATCATGGTTTTACATTAATCGAGCTTATGGTTGTGGTTGTAATCGTGGCTTTATTAGCCGCGATTGC
ACTGCCTAGTTATCAGCAATACATCAGAAAGAAAGATATGGCACTTGCTCAGCAAGAAATGCTTAAACTAGCAGATCAGC
TAGAAAGACATAAAGCAAAAAATTTTTCTTATAAAAAGTTTGATCCTAAATATCTATATTCTGGAATAACAACGCCATTA
AATGTTGTGTATGTACCTGGTGGAATTTCTACGGCTAAATCCAAATATAAAATTGAGATTAAAGATATAAGTAATTCAAC
GGAAGTGGACTTACTAACATCGAGCTTAGGTAAAGCATGGTCAATGAAAGCTTCTCCTATAAATTCAAGTGACGCATTGC
TTTACACATTTTTAATAACCAGTCATGGTATAAAGTGCAAAGCGAAAGAAGCTGAGAATGTGTCATTTACAGCATGTTCA
GGGCAAGGAGCAGAAGATTGGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Acinetobacter baylyi ADP1

46.893

100

0.497

  pilY2 Acinetobacter baumannii D1279779

38.365

95.21

0.365


Multiple sequence alignment