Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL140_RS01660 Genome accession   NZ_LR134336
Coordinates   326130..326762 (+) Length   210 a.a.
NCBI ID   WP_000698402.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 321130..331762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS01645 (NCTC11427_00322) - 321553..324072 (+) 2520 WP_000734390.1 SEC10/PgrA surface exclusion domain-containing protein -
  EL140_RS01650 (NCTC11427_00323) liaF 324426..325124 (+) 699 WP_000714491.1 cell wall-active antibiotics response protein LiaF -
  EL140_RS01655 (NCTC11427_00324) - 325121..326119 (+) 999 WP_000744931.1 sensor histidine kinase -
  EL140_RS01660 (NCTC11427_00325) vraR 326130..326762 (+) 633 WP_000698402.1 response regulator Regulator
  EL140_RS01665 (NCTC11427_00326) - 326763..327419 (+) 657 WP_000050041.1 DNA alkylation repair protein -
  EL140_RS01670 (NCTC11427_00327) tig 327510..328793 (+) 1284 WP_000116506.1 trigger factor -
  EL140_RS01675 (NCTC11427_00328) recD/recD2/recDB 328841..331210 (-) 2370 WP_000454456.1 ATP-dependent RecD-like DNA helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23603.18 Da        Isoelectric Point: 4.7177

>NTDB_id=1001978 EL140_RS01660 WP_000698402.1 326130..326762(+) (vraR) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHALRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1001978 EL140_RS01660 WP_000698402.1 326130..326762(+) (vraR) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTATTTTGATCTCCAAGACGATGTGGA
AGTTGTGGGCGAGGCTGCCAATGGGGCTCAAGGTATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGATGCAACCTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAGATATTAATTGTC
ACCTCTTACTTGGACAATGAAAAAATCATGCCGGTCTTGAACGCTGGTGCCAAAGGCTATATGCTTAAGACTTCAAGTGC
AGATGAATTGCTCCATGCTCTCCGTAAGGTGGCTGCTGGCGAGCTGGCTATTGAACAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGTAATCATATGGAGCTTCATGAGGAGCTGACTGCGCGTGAGCGAGACGTACTTCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGGATTGCAGATGAACTCTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCCAATATCCTTGCTAAACT
TGAGGTCAGCGATCGCACCCAGGCGGCGGTCTATGCCTTCCAGCACCACTTGGTCGGGCAGGAGGACTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405