Detailed information NTG1001222

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EL107_RS08780
• Genome accession: NZ_LR134314
• Coordinates: 1704009..1705010 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain NCTC8302
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1699009..1710010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL107_RS08755 (NCTC8302_01732)	-	1699683..1700366 (-)	684	WP_021340135.1	DUF969 domain-containing protein	-
EL107_RS08760 (NCTC8302_01733)	-	1700577..1701503 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
EL107_RS08765 (NCTC8302_01734)	-	1701648..1702025 (-)	378	WP_002985686.1	VOC family protein	-
EL107_RS08770 (NCTC8302_01735)	-	1702036..1702701 (-)	666	WP_011184275.1	NAD(P)H-dependent oxidoreductase	-
EL107_RS08775 (NCTC8302_01736)	-	1702750..1703835 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
EL107_RS08780 (NCTC8302_01737)	ccpA	1704009..1705010 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EL107_RS08785 (NCTC8302_01738)	-	1705141..1706139 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EL107_RS08790 (NCTC8302_01739)	-	1706141..1707475 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
EL107_RS08795 (NCTC8302_01741)	thrS	1707897..1709840 (+)	1944	WP_011184277.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1001222 EL107_RS08780 WP_002985680.1 1704009..1705010(+) (ccpA) [Streptococcus pyogenes strain NCTC8302]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1001222 EL107_RS08780 WP_002985680.1 1704009..1705010(+) (ccpA) [Streptococcus pyogenes strain NCTC8302]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGATTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559