Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   EL070_RS09655 Genome accession   NZ_LR134284
Coordinates   1831514..1832110 (-) Length   198 a.a.
NCBI ID   WP_002991359.1    Uniprot ID   Q1JJH3
Organism   Streptococcus pyogenes strain NCTC8232     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1826514..1837110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS09620 (NCTC8232_01925) - 1826576..1826881 (-) 306 WP_111705836.1 DUF1292 domain-containing protein -
  EL070_RS09625 (NCTC8232_01926) ruvX 1826893..1827312 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  EL070_RS09630 (NCTC8232_01927) - 1827309..1827578 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EL070_RS09635 (NCTC8232_01928) spx 1827691..1828089 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EL070_RS09640 (NCTC8232_01929) recA 1828379..1829515 (-) 1137 WP_111705837.1 recombinase RecA Machinery gene
  EL070_RS09645 (NCTC8232_01930) cinA 1829604..1830875 (-) 1272 WP_111705838.1 competence/damage-inducible protein A Machinery gene
  EL070_RS09650 (NCTC8232_01931) - 1830944..1831504 (-) 561 WP_030127533.1 DNA-3-methyladenine glycosylase I -
  EL070_RS09655 (NCTC8232_01932) ruvA 1831514..1832110 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  EL070_RS09660 (NCTC8232_01933) - 1832112..1833332 (-) 1221 WP_014612636.1 MDR family MFS transporter -
  EL070_RS09665 (NCTC8232_01934) hexB 1833343..1835325 (-) 1983 WP_011018317.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21841.15 Da        Isoelectric Point: 6.2537

>NTDB_id=1000074 EL070_RS09655 WP_002991359.1 1831514..1832110(-) (ruvA) [Streptococcus pyogenes strain NCTC8232]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=1000074 EL070_RS09655 WP_002991359.1 1831514..1832110(-) (ruvA) [Streptococcus pyogenes strain NCTC8232]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCATACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTGTTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JJH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae R6

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae D39

67.513

99.495

0.672
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment