93224

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF1/-
Location 1677042..1677380 Replicon chromosome
Accession NZ_CP026079
Organism Staphylococcus aureus strain FDAARGOS_9

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag RK67_RS08670 Protein ID WP_011447039.1
Coordinates 1677042..1677218 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1677206..1677380 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK67_RS08650 1674730..1674882 + 153 WP_001000058.1 hypothetical protein -
RK67_RS08655 1674928..1675215 + 288 WP_001262621.1 hypothetical protein -
RK67_RS08660 1675271..1675645 + 375 WP_000340977.1 hypothetical protein -
RK67_RS08665 1676066..1676839 + 774 WP_025174055.1 staphylococcal enterotoxin type P -
RK67_RS08670 1677042..1677218 + 177 WP_011447039.1 putative holin-like toxin Toxin
- 1677206..1677380 - 175 - - Antitoxin
RK67_RS08680 1677430..1677684 + 255 WP_000611512.1 phage holin -
RK67_RS08685 1677696..1678451 + 756 WP_000861026.1 CHAP domain-containing protein -
RK67_RS08690 1678642..1679133 + 492 WP_000920042.1 staphylokinase -
RK67_RS08705 1679780..1680114 + 335 Protein_1622 SH3 domain-containing protein -
RK67_RS08710 1680209..1680658 - 450 WP_000727645.1 chemotaxis-inhibiting protein CHIPS -
RK67_RS08715 1681341..1681691 + 351 WP_000702262.1 complement inhibitor SCIN-A -
RK67_RS08720 1681744..1682004 - 261 WP_001791826.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - groEL / tsst-1 / sec / sell / hlb / see / sak / chp / scn 1613902..1681691 67789


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T93224 WP_011447039.1 NZ_CP026079:1677042-1677218 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

>T93224 NZ_CP026079:1677042-1677218 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 175 bp

>AT93224 NZ_CP026079:c1677380-1677206 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References