Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-ratA/Fst(toxin)
Location 25247..25499 Replicon plasmid pA
Accession NZ_CP019513
Organism Enterococcus faecalis strain CLB21560

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag BZG32_RS16345 Protein ID WP_107164701.1
Coordinates 25389..25499 (-) Length 37 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 25247..25349 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG32_RS16315 21333..22343 - 1011 WP_002365949.1 replication initiator protein A -
BZG32_RS16325 22815..23660 + 846 WP_000239313.1 AAA family ATPase -
BZG32_RS16330 23653..24024 + 372 WP_000049959.1 replication-associated protein RepC -
BZG32_RS16335 24128..24418 - 291 WP_002365947.1 hypothetical protein -
BZG32_RS16340 24589..25050 - 462 WP_002365946.1 hypothetical protein -
- 25247..25349 + 103 NuclAT_0 - Antitoxin
- 25247..25349 + 103 NuclAT_0 - Antitoxin
- 25247..25349 + 103 NuclAT_0 - Antitoxin
- 25247..25349 + 103 NuclAT_0 - Antitoxin
BZG32_RS16345 25389..25499 - 111 WP_107164701.1 type I toxin-antitoxin system Fst family toxin Toxin
BZG32_RS16355 25750..26100 - 351 WP_002365943.1 hypothetical protein -
BZG32_RS16360 26097..27425 - 1329 WP_002387639.1 Y-family DNA polymerase -
BZG32_RS16365 27852..28154 - 303 WP_002365939.1 hypothetical protein -
BZG32_RS16370 28166..28375 - 210 WP_002387638.1 hypothetical protein -
BZG32_RS16375 28436..28660 - 225 WP_010708492.1 hypothetical protein -
BZG32_RS16380 28654..28941 - 288 WP_010708491.1 hypothetical protein -
BZG32_RS16385 28958..29578 - 621 WP_021732893.1 recombinase family protein -
BZG32_RS16390 29755..30018 + 264 WP_000245205.1 PbsX family transcriptional regulator -
BZG32_RS16395 30012..30374 + 363 WP_000241511.1 type II toxin-antitoxin system PemK/MazF family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid aac(6')-aph(2'') / qacZ / dfrG asa1 1..66602 66602


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 4090.89 Da        Isoelectric Point: 4.1672

>T72611 WP_107164701.1 NZ_CP019513:c25499-25389 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Download         Length: 111 bp

>T72611 NZ_CP019513:c25499-25389 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCAATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAGCCGAAAGTAA

Antitoxin


Download         Length: 103 bp

>AT72611 NZ_CP019513:25247-25349 [Enterococcus faecalis]
TTGACCCAAAATAAAAATATGCTATACTAAAAGTGCGAAACGACATTAAATCGTACAGATAACACAAAAAGCAATCCTAC
GGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References