Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2126455..2126600 Replicon chromosome
Accession NZ_AP023317
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4681

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2126495..2126598 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2126455..2126600 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5693_RS10335 2122881..2123579 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5693_RS10340 2123603..2124259 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5693_RS10345 2124367..2124597 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5693_RS10350 2124735..2125109 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5693_RS10355 2125110..2125985 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5693_RS10360 2126002..2126355 + 354 WP_000722368.1 YebY family protein -
- 2126455..2126600 - 146 - - Antitoxin
- 2126495..2126598 + 104 - - Toxin
K5693_RS10365 2126729..2127652 - 924 Protein_2037 tyrosine-type recombinase/integrase -
K5693_RS25155 2127916..2128377 - 462 Protein_2038 DNA breaking-rejoining protein -
K5693_RS10375 2128366..2128557 + 192 Protein_2039 glycoside hydrolase family 19 protein -
K5693_RS10380 2128611..2129144 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5693_RS10385 2129401..2129568 - 168 WP_000789530.1 lytic enzyme -
K5693_RS10390 2129633..2129821 - 189 WP_001521334.1 hypothetical protein -
K5693_RS10395 2129876..2130136 + 261 Protein_2043 DUF1441 family protein -
K5693_RS10400 2130351..2130695 + 345 Protein_2044 macro domain-containing protein -
K5693_RS10405 2130705..2131175 + 471 Protein_2045 tail fiber assembly protein -
K5693_RS10410 2131272..2131472 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2106458..2159112 52654


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37557 NZ_AP023317:2126495-2126598 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37557 NZ_AP023317:c2126600-2126455 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References