265256

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-MW1433/-
Location 334524..334831 Replicon chromosome
Accession NZ_CP113039
Organism Staphylococcus aureus strain Gwen

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag OS086_RS01800 Protein ID WP_011447039.1
Coordinates 334655..334831 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name MW1433
Locus tag -
Coordinates 334524..334663 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS086_RS01760 (329869) 329869..330129 + 261 WP_001791826.1 hypothetical protein -
OS086_RS01765 (330182) 330182..330532 - 351 WP_000702262.1 complement inhibitor SCIN-A -
OS086_RS01770 (331215) 331215..331664 + 450 WP_000727645.1 chemotaxis-inhibiting protein CHIPS -
OS086_RS01775 (331759) 331759..332093 - 335 Protein_317 SH3 domain-containing protein -
OS086_RS01780 (332740) 332740..333231 - 492 WP_000920042.1 staphylokinase -
OS086_RS01785 (333422) 333422..334177 - 756 WP_000861026.1 CHAP domain-containing protein -
OS086_RS01790 (334189) 334189..334443 - 255 WP_000611512.1 phage holin -
OS086_RS01795 (334495) 334495..334602 + 108 WP_031762631.1 hypothetical protein -
- (334524) 334524..334663 + 140 NuclAT_0 - Antitoxin
- (334524) 334524..334663 + 140 NuclAT_0 - Antitoxin
- (334524) 334524..334663 + 140 NuclAT_0 - Antitoxin
- (334524) 334524..334663 + 140 NuclAT_0 - Antitoxin
OS086_RS01800 (334655) 334655..334831 - 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
OS086_RS01805 (335034) 335034..335807 - 774 WP_025174055.1 staphylococcal enterotoxin type P -
OS086_RS01810 (336228) 336228..336602 - 375 WP_000340977.1 hypothetical protein -
OS086_RS01815 (336658) 336658..336945 - 288 WP_001262621.1 hypothetical protein -
OS086_RS01820 (336991) 336991..337143 - 153 WP_001000058.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - scn / chp / sak / see / hlb / sell / sec / tsst-1 / groEL 330182..397972 67790


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T265256 WP_011447039.1 NZ_CP113039:c334831-334655 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 140 bp

>AT265256 NZ_CP113039:334524-334663 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References