Detailed information of TA system TA026341

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): CD-RCd/-
• Location: 1716988..1717208
• Replicon: chromosome
• Accession: NC_017179
• Organism: Clostridium difficile BI1

Toxin (Protein)

• Gene name: CD0956.2
• Uniprot ID: Q183Z5
• Locus tag: CDBI1_RS08020
• Protein ID: WP_003429855.1
• Coordinates: 1716988..1717149 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	RCd10
Locus tag	-
Coordinates	1717069..1717208 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDBI1_RS07990	1712845..1713282	+	438	WP_009888839.1	hypothetical protein	-
CDBI1_RS07995	1713275..1713451	+	177	WP_009888840.1	hypothetical protein	-
CDBI1_RS08000	1713452..1714762	+	1311	WP_009893136.1	phage tail sheath family protein	-
CDBI1_RS08005	1714779..1715249	+	471	WP_009888842.1	phage tail tube protein	-
CDBI1_RS08010	1715308..1716135	+	828	WP_009888843.1	hypothetical protein	-
CDBI1_RS08015	1716207..1716647	+	441	WP_003429853.1	phage portal protein	-
CDBI1_RS08020	1716988..1717149	+	162	WP_003429855.1	hypothetical protein	Toxin
-	1717069..1717208	-	140	NuclAT_1	-	Antitoxin
-	1717069..1717208	-	140	NuclAT_2	-	Antitoxin
-	1717553..1717601	-	49	NuclAT_4	-	-
-	1717553..1717601	-	49	NuclAT_5	-	-
CDBI1_RS08025	1718486..1718674	+	189	WP_003429858.1	hypothetical protein	-
CDBI1_RS08030	1718793..1719659	+	867	WP_009888845.1	hypothetical protein	-
CDBI1_RS08035	1720524..1721051	+	528	WP_009888847.1	DUF4352 domain-containing protein	-
CDBI1_RS08040	1721189..1721956	+	768	WP_009888848.1	DUF4428 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_013316 Clostridium difficile R20291 Prophage TA024266 1671047..1738184 0	inside	Prophage	-	-	1683199..1749635	66436

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 6120.42 Da
• Isoelectric Point: 10.8938

>T26341 WP_003429855.1 NC_017179:1716988-1717149 [Clostridioides difficile BI1]
MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFDFKIKFHKFK

Nucleotide

• Length: 162 bp

>T26341 NC_017179:1716988-1717149 [Clostridioides difficile BI1]
ATGAATAACTTTTTACTTAATGTAATAGCTGGCGTTATTGCTAGTTTAATATTTTGCTTAATTTGTAAAGTATTTCTAAA
AGTAAAAAGCCACTCAACTCGTGGCAAGAGTAAAAGTGGCTGGGAATTTGATTTTAAAATCAAGTTCCACAAATTTAAAT
AA

Antitoxin

Nucleotide

• Length: 140 bp

>AT26341 NC_017179:c1717208-1717069 [Clostridioides difficile BI1]
AAGAAGAACTACAATCTATTTGACAGTAGAGTGAAGTTCATAATTTAAACAATTAGTAATTATTTAAATTTGTGGAACTT
GATTTTAAAATCAAATTCCCAGCCACTTTTACTCTTGCCACGAGTTGAGTGGCTTTTTAC

Structures

Toxin

• AlphaFold DB: A0A069AVN2

Antitoxin