Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1700632..1700852 Replicon chromosome
Accession NC_017178
Organism Clostridium difficile 2007855

Toxin (Protein)


Gene name CD0956.2 Uniprot ID Q183Z5
Locus tag CD7855_RS07930 Protein ID WP_003429855.1
Coordinates 1700632..1700793 (+) Length 54 a.a.

Antitoxin (RNA)


Gene name RCd10
Locus tag -
Coordinates 1700713..1700852 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD7855_RS07900 1696489..1696926 + 438 WP_009888839.1 hypothetical protein -
CD7855_RS07905 1696919..1697095 + 177 WP_009888840.1 hypothetical protein -
CD7855_RS07910 1697096..1698406 + 1311 WP_009893136.1 phage tail sheath family protein -
CD7855_RS07915 1698423..1698893 + 471 WP_009888842.1 phage tail tube protein -
CD7855_RS07920 1698952..1699779 + 828 WP_009888843.1 hypothetical protein -
CD7855_RS07925 1699851..1700291 + 441 WP_003429853.1 phage portal protein -
CD7855_RS07930 1700632..1700793 + 162 WP_003429855.1 hypothetical protein Toxin
- 1700713..1700852 - 140 NuclAT_1 - Antitoxin
- 1700713..1700852 - 140 NuclAT_2 - Antitoxin
- 1701197..1701245 - 49 NuclAT_4 - -
- 1701197..1701245 - 49 NuclAT_5 - -
CD7855_RS07935 1702130..1702318 + 189 WP_003429858.1 hypothetical protein -
CD7855_RS07940 1702436..1703302 + 867 WP_009888845.1 hypothetical protein -
CD7855_RS07945 1704167..1704694 + 528 WP_009888847.1 DUF4352 domain-containing protein -
CD7855_RS07950 1704832..1705599 + 768 WP_009888848.1 DUF4428 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1666842..1733279 66437


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6120.42 Da        Isoelectric Point: 10.8938

>T26337 WP_003429855.1 NC_017178:1700632-1700793 [Clostridioides difficile 2007855]
MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFDFKIKFHKFK

Download         Length: 162 bp

>T26337 NC_017178:1700632-1700793 [Clostridioides difficile 2007855]
ATGAATAACTTTTTACTTAATGTAATAGCTGGCGTTATTGCTAGTTTAATATTTTGCTTAATTTGTAAAGTATTTCTAAA
AGTAAAAAGCCACTCAACTCGTGGCAAGAGTAAAAGTGGCTGGGAATTTGATTTTAAAATCAAGTTCCACAAATTTAAAT
AA

Antitoxin


Download         Length: 140 bp

>AT26337 NC_017178:c1700852-1700713 [Clostridioides difficile 2007855]
AAGAAGAACTACAATCTATTTGACAGTAGAGTGAAGTTCATAATTTAAACAATTAGTAATTATTTAAATTTGTGGAACTT
GATTTTAAAATCAAATTCCCAGCCACTTTTACTCTTGCCACGAGTTGAGTGGCTTTTTAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069AVN2

Antitoxin

Download structure file

References