Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1979049..1979192 Replicon chromosome
Accession NZ_CP082929
Organism Salmonella enterica subsp. enterica serovar London isolate N18-04674

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1979088..1979190 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1979049..1979192 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6991_RS09465 1975473..1976171 - 699 WP_023255939.1 exodeoxyribonuclease X -
K6991_RS09470 1976195..1976851 - 657 WP_023245437.1 carbon-nitrogen hydrolase family protein -
K6991_RS09475 1976959..1977189 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K6991_RS09480 1977327..1977701 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K6991_RS09485 1977702..1978577 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
K6991_RS09490 1978594..1978947 + 354 WP_000722368.1 YebY family protein -
- 1979049..1979192 - 144 - - Antitoxin
- 1979088..1979190 + 103 - - Toxin
K6991_RS09495 1979330..1980409 - 1080 WP_058107134.1 phage integrase Arm DNA-binding domain-containing protein -
K6991_RS09500 1980442..1981593 - 1152 Protein_1855 PD-(D/E)XK nuclease-like domain-containing protein -
K6991_RS09505 1981582..1981773 + 192 Protein_1856 glycoside hydrolase family 19 protein -
K6991_RS09510 1981827..1982360 + 534 WP_023256014.1 DUF2514 domain-containing protein -
K6991_RS09515 1982617..1982784 - 168 WP_000789530.1 lytic enzyme -
K6991_RS09520 1982849..1983037 - 189 WP_001034748.1 hypothetical protein -
K6991_RS09525 1983092..1983352 + 261 Protein_1860 DUF1441 family protein -
K6991_RS09530 1983354..1983569 + 216 Protein_1861 shikimate transporter -
K6991_RS09535 1983579..1983866 + 288 Protein_1862 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 1973385..2012286 38901


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215634 NZ_CP082929:1979088-1979190 [Salmonella enterica subsp. enterica serovar London]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT215634 NZ_CP082929:c1979192-1979049 [Salmonella enterica subsp. enterica serovar London]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References