Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 59679..59943 | Replicon | plasmid unnamed476 |
Accession | NZ_CP062866 | ||
Organism | Escherichia coli O39:H21 strain Res13-Lact-PEB08-01 |
Toxin (Protein)
Gene name | pndA | Uniprot ID | U9Y6M3 |
Locus tag | IMP90_RS23250 | Protein ID | WP_001331364.1 |
Coordinates | 59791..59943 (+) | Length | 51 a.a. |
Antitoxin (RNA)
Gene name | pndB | ||
Locus tag | - | ||
Coordinates | 59679..59736 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IMP90_RS23235 | 54918..57209 | - | 2292 | WP_001289276.1 | hypothetical protein | - |
IMP90_RS23240 | 57202..58272 | - | 1071 | WP_000151583.1 | IncI1-type conjugal transfer protein TrbB | - |
IMP90_RS23245 | 58291..59499 | - | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
- | 59679..59736 | - | 58 | NuclAT_0 | - | Antitoxin |
- | 59679..59736 | - | 58 | NuclAT_0 | - | Antitoxin |
- | 59679..59736 | - | 58 | NuclAT_0 | - | Antitoxin |
- | 59679..59736 | - | 58 | NuclAT_0 | - | Antitoxin |
IMP90_RS23250 | 59791..59943 | + | 153 | WP_001331364.1 | Hok/Gef family protein | Toxin |
IMP90_RS23255 | 60015..60266 | - | 252 | WP_001291964.1 | hypothetical protein | - |
IMP90_RS23260 | 60925..61101 | - | 177 | WP_001054904.1 | hypothetical protein | - |
IMP90_RS23265 | 61493..61702 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
IMP90_RS23270 | 61774..62424 | - | 651 | WP_001178506.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
IMP90_RS23275 | 62498..64666 | - | 2169 | WP_021537350.1 | DotA/TraY family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Conjugative plasmid | dfrA17 / aadA5 / sul2 / blaCTX-M-1 | - | 1..109586 | 109586 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5775.13 Da Isoelectric Point: 8.7948
>T176980 WP_001331364.1 NZ_CP062866:59791-59943 [Escherichia coli O39:H21]
MPQRTFLMMLIVICVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVICVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
>T176980 NZ_CP062866:59791-59943 [Escherichia coli O39:H21]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
Antitoxin
Download Length: 58 bp
>AT176980 NZ_CP062866:c59736-59679 [Escherichia coli O39:H21]
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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