Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-MW1433/- |
Location | 2091307..2091614 | Replicon | chromosome |
Accession | NZ_CP033977 | ||
Organism | Staphylococcus aureus strain P2D15C1 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | Q2FWU9 |
Locus tag | EFD78_RS10500 | Protein ID | WP_011447039.1 |
Coordinates | 2091438..2091614 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | MW1433 | ||
Locus tag | - | ||
Coordinates | 2091307..2091446 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EFD78_RS10460 | 2086652..2086912 | + | 261 | WP_001791826.1 | hypothetical protein | - |
EFD78_RS10465 | 2086965..2087315 | - | 351 | WP_000702262.1 | complement inhibitor SCIN-A | - |
EFD78_RS10470 | 2087998..2088447 | + | 450 | WP_000727645.1 | chemotaxis-inhibiting protein CHIPS | - |
EFD78_RS10475 | 2088542..2088876 | - | 335 | Protein_1981 | SH3 domain-containing protein | - |
EFD78_RS10480 | 2089523..2090014 | - | 492 | WP_000920042.1 | staphylokinase | - |
EFD78_RS10485 | 2090205..2090960 | - | 756 | WP_002955266.1 | CHAP domain-containing protein | - |
EFD78_RS10490 | 2090972..2091226 | - | 255 | WP_000611512.1 | phage holin | - |
EFD78_RS10495 | 2091278..2091385 | + | 108 | WP_031762631.1 | hypothetical protein | - |
- | 2091307..2091446 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2091307..2091446 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2091307..2091446 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2091307..2091446 | + | 140 | NuclAT_0 | - | Antitoxin |
EFD78_RS10500 | 2091438..2091614 | - | 177 | WP_011447039.1 | putative holin-like toxin | Toxin |
EFD78_RS10505 | 2091817..2092590 | - | 774 | WP_025174055.1 | staphylococcal enterotoxin type P | - |
EFD78_RS10510 | 2093011..2093385 | - | 375 | WP_000340977.1 | hypothetical protein | - |
EFD78_RS10515 | 2093441..2093728 | - | 288 | WP_001262621.1 | hypothetical protein | - |
EFD78_RS10520 | 2093774..2093926 | - | 153 | WP_001000058.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / chp / sak / see / hlb / groEL | 2086965..2139145 | 52180 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6849.45 Da Isoelectric Point: 10.6777
>T114767 WP_011447039.1 NZ_CP033977:c2091614-2091438 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Download Length: 177 bp
>T114767 NZ_CP033977:c2091614-2091438 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
Antitoxin
Download Length: 140 bp
>AT114767 NZ_CP033977:2091307-2091446 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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