MGE detailed information
MGE type: Conjugative plasmid MGE length: 126618 bp
Accession: NZ_LR890607 Location: 1..126618 Organism: Escherichia coli isolate MINF_8D-sc-2280460 Replicon: plasmid 2
Accession: NZ_LR890607 Location: 1..126618 Organism: Escherichia coli isolate MINF_8D-sc-2280460 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW69_RS23280 () | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| JMW69_RS23285 () | 1263..2003 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| JMW69_RS23290 () | 2124..2303 | - | 180 | WP_042347974.1 | hypothetical protein | - |
| JMW69_RS23295 () | 2670..3839 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| JMW69_RS23300 () | 4065..4240 | - | 176 | Protein_4 | IS3 family transposase | - |
| JMW69_RS23305 () | 4686..4958 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| JMW69_RS23310 () | 5483..5919 | - | 437 | Protein_6 | IS3 family transposase IS2 | Transposase |
| JMW69_RS23315 () | 6201..8171 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| JMW69_RS23320 () | 8178..8969 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| JMW69_RS23325 () | 9032..9640 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| JMW69_RS23330 () | 9708..10490 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| JMW69_RS23335 () | 10487..11509 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| JMW69_RS23340 () | 11595..12540 | - | 946 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| JMW69_RS23345 () | 12589..12936 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| JMW69_RS23350 () | 12933..13337 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| JMW69_RS23355 () | 13366..13749 | - | 384 | Protein_15 | IS3 family transposase IS629 | Transposase |
| JMW69_RS23360 () | 13839..15347 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| JMW69_RS23365 () | 16020..16759 | - | 740 | Protein_17 | IS3 family transposase IS629 | Transposase |
| JMW69_RS23370 () | 16785..17090 | + | 306 | Protein_18 | IS91 family transposase ISSbo1 | Transposase |
| JMW69_RS23375 () | 17613..18788 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| JMW69_RS23380 () | 18857..21118 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| JMW69_RS23385 () | 21287..22063 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| JMW69_RS23390 () | 22071..22946 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| JMW69_RS23395 () | 23278..23825 | - | 548 | Protein_23 | replication initiation protein | - |
| JMW69_RS23400 () | 25397..25732 | - | 336 | WP_001080732.1 | colicin transporter | - |
| JMW69_RS23405 () | 25861..26208 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| JMW69_RS23410 () | 26228..26737 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| JMW69_RS23415 () | 26734..26994 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| JMW69_RS23420 () | 27096..27835 | + | 740 | Protein_28 | IS3 family transposase IS629 | Transposase |
| JMW69_RS23425 () | 28508..28822 | + | 315 | Protein_29 | IS5 family transposase ISKpn26 | Transposase |
| JMW69_RS23430 () | 28823..28996 | + | 174 | Protein_30 | IS5 family transposase ISKpn26 | Transposase |
| JMW69_RS23435 () | 29146..29779 | - | 634 | Protein_31 | histidine-type phosphatase | - |
| JMW69_RS23440 () | 29901..30386 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| JMW69_RS23445 () | 30411..30896 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| JMW69_RS23450 () | 30883..31578 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| JMW69_RS23455 () | 31583..32713 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| JMW69_RS23460 () | 32703..33986 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| JMW69_RS23465 () | 33989..35368 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| JMW69_RS23470 () | 35472..35999 | - | 528 | WP_000178050.1 | iron transporter | - |
| JMW69_RS23475 () | 36040..37926 | - | 1887 | WP_201524959.1 | FTR1 family iron permease | - |
| JMW69_RS23480 () | 38273..39088 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| JMW69_RS23485 () | 39271..39777 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| JMW69_RS23490 () | 39767..39925 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| JMW69_RS23495 () | 40075..40188 | - | 114 | Protein_43 | IS6 family transposase | - |
| JMW69_RS23500 () | 40388..41085 | + | 698 | Protein_44 | IS1 family transposase IS1X2 | Transposase |
| JMW69_RS23505 () | 41100..41318 | + | 219 | Protein_45 | IS4 family transposase | - |
| JMW69_RS23510 () | 41368..42072 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JMW69_RS23515 () | 42131..42880 | - | 750 | Protein_47 | IS91 family transposase ISAzo26 | Transposase |
| JMW69_RS23520 () | 43038..43511 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| JMW69_RS23525 () | 43642..44430 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| JMW69_RS23530 () | 44636..44983 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| JMW69_RS23535 () | 44977..45816 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| JMW69_RS23540 () | 45944..46147 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| JMW69_RS23545 () | 46303..47508 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| JMW69_RS23550 () | 47519..47824 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| JMW69_RS23555 () | 47868..47933 | + | 66 | Protein_55 | EAL domain-containing protein | - |
| JMW69_RS23560 () | 48051..48815 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| JMW69_RS23565 () | 49308..49892 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| JMW69_RS23570 () | 49892..51130 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| JMW69_RS23575 () | 51127..52041 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| JMW69_RS23580 () | 52163..52867 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| JMW69_RS23585 () | 53002..53097 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| JMW69_RS23590 () | 53223..53960 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| JMW69_RS23595 () | 53905..54075 | + | 171 | WP_170852050.1 | rRNA adenine methyltransferase | - |
| JMW69_RS23600 () | 54590..55039 | + | 450 | WP_013362817.1 | hypothetical protein | - |
| JMW69_RS23605 () | 55000..55341 | + | 342 | WP_023909256.1 | 60 kDa chaperonin | VF |
| JMW69_RS23610 () | 55568..57049 | + | 1482 | WP_024210412.1 | IS91 family transposase ISVsa3 | Transposase |
| JMW69_RS23615 () | 57061..57765 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JMW69_RS23620 () | 57831..58376 | + | 546 | Protein_68 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JMW69_RS23625 () | 58412..58827 | - | 416 | Protein_69 | IS1 family transposase | - |
| JMW69_RS23630 () | 59076..59477 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JMW69_RS23635 () | 59410..59667 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JMW69_RS23640 () | 59760..60413 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JMW69_RS23645 () | 61353..62210 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| JMW69_RS23650 () | 62203..62277 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| JMW69_RS23655 () | 62274..62408 | - | 135 | Protein_75 | protein CopA/IncA | - |
| JMW69_RS23660 () | 62514..62768 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| JMW69_RS23665 () | 63065..63199 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 63244..63304 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - () | 63244..63304 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - () | 63244..63304 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - () | 63244..63304 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| JMW69_RS23670 () | 63271..63557 | - | 287 | Protein_78 | DUF2726 domain-containing protein | - |
| JMW69_RS23675 () | 64070..64282 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| JMW69_RS23680 () | 64413..64973 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| JMW69_RS23685 () | 65028..65774 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| JMW69_RS23690 () | 65794..71064 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| JMW69_RS23695 () | 71064..73343 | - | 2280 | WP_201524957.1 | Coupling protein TraD | VF |
| JMW69_RS23700 () | 73340..74119 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| JMW69_RS23705 () | 74322..75053 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| JMW69_RS23710 () | 75085..75582 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| JMW69_RS23715 () | 75601..78420 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JMW69_RS23720 () | 78417..79790 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| JMW69_RS23725 () | 79777..80202 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| JMW69_RS23730 () | 80150..80496 | - | 347 | Protein_90 | P-type conjugative transfer protein TrbJ | - |
| JMW69_RS23735 () | 80426..80971 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JMW69_RS23740 () | 80958..81242 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JMW69_RS23745 () | 81369..81689 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| JMW69_RS23750 () | 81737..82434 | - | 698 | Protein_94 | IS1 family transposase IS1G | Transposase |
| JMW69_RS23755 () | 82480..82614 | - | 135 | Protein_95 | TraY domain-containing protein | - |
| JMW69_RS23760 () | 82702..83379 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| JMW69_RS23765 () | 83513..83896 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| JMW69_RS23770 () | 84227..84829 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| JMW69_RS23775 () | 85126..85947 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| JMW69_RS23780 () | 86066..86353 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| JMW69_RS23785 () | 86378..86584 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| JMW69_RS23790 () | 87275..87433 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 87477..87701 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 87477..87701 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 87477..87701 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 87477..87701 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| JMW69_RS23795 () | 87513..87701 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| JMW69_RS23800 () | 87713..88432 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| JMW69_RS23805 () | 88429..88863 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| JMW69_RS23810 () | 88918..90876 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| JMW69_RS23815 () | 90942..91175 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| JMW69_RS23820 () | 91238..91777 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| JMW69_RS23825 () | 92420..92674 | - | 255 | WP_047605447.1 | hypothetical protein | - |
| JMW69_RS23830 () | 92700..93263 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| JMW69_RS23835 () | 93311..94672 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| JMW69_RS23840 () | 94724..94954 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| JMW69_RS23845 () | 95989..96180 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| JMW69_RS23850 () | 96177..96599 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| JMW69_RS23855 () | 96646..96948 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| JMW69_RS23860 () | 97488..98264 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| JMW69_RS23865 () | 98315..98749 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| JMW69_RS23870 () | 98763..98984 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| JMW69_RS23875 () | 98985..99668 | - | 684 | WP_000086185.1 | DNA methylase | - |
| JMW69_RS23880 () | 99745..100049 | - | 305 | Protein_120 | hypothetical protein | - |
| JMW69_RS23885 () | 100053..100955 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| JMW69_RS23890 () | 101822..102793 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JMW69_RS23895 () | 102793..103959 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| JMW69_RS23900 () | 104547..105302 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| JMW69_RS23905 () | 106022..106828 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| JMW69_RS23910 () | 106829..107134 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JMW69_RS23915 () | 107136..107354 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| JMW69_RS23920 () | 108062..109057 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| JMW69_RS23925 () | 109061..109993 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| JMW69_RS23930 () | 110130..110827 | - | 698 | Protein_130 | IS1 family transposase IS1G | Transposase |
| JMW69_RS23935 () | 111041..114157 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| JMW69_RS23940 () | 114279..115562 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| JMW69_RS23945 () | 115559..117115 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| JMW69_RS23950 () | 117298..117519 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| JMW69_RS23955 () | 117519..117899 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| JMW69_RS23960 () | 117904..118083 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| JMW69_RS23965 () | 118111..118470 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| JMW69_RS23970 () | 118394..118768 | + | 375 | Protein_138 | IS3 family transposase ISEc52 | Transposase |
| JMW69_RS23975 () | 118797..119494 | + | 698 | Protein_139 | IS1 family transposase IS1R | Transposase |
| JMW69_RS23980 () | 119730..120746 | - | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| JMW69_RS23985 () | 120954..122357 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| JMW69_RS23990 () | 122344..123276 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| JMW69_RS23995 () | 123385..123714 | - | 330 | Protein_143 | TOBE domain-containing protein | - |
| JMW69_RS24000 () | 123730..124427 | - | 698 | Protein_144 | IS1 family transposase IS1R | Transposase |
| JMW69_RS24005 () | 124485..124733 | + | 249 | Protein_145 | abortive infection family protein | - |
| JMW69_RS24010 () | 125102..125833 | - | 732 | WP_001617898.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|