MGE detailed information

MGE type: Conjugative plasmid        MGE length: 173787 bp
Accession: NZ_LR890289        Location: 1..173787         Organism: Escherichia coli isolate MSB1_1A-sc-2280383       Replicon: plasmid 2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW08_RS22925 () 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
JMW08_RS22930 () 1263..2003 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
JMW08_RS22935 () 2124..2312 - 189 WP_001309252.1 hypothetical protein -
JMW08_RS22940 () 2679..3848 + 1170 WP_001072358.1 hypothetical protein -
JMW08_RS22945 () 4074..4249 - 176 Protein_4 IS3 family transposase -
JMW08_RS22950 () 4695..4967 - 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
JMW08_RS22955 () 5492..5928 - 437 Protein_6 IS3 family transposase IS2 Transposase
JMW08_RS22960 () 6210..8180 + 1971 WP_001496335.1 Hemin receptor VF
JMW08_RS22965 () 8187..8978 + 792 WP_000977394.1 DUF4198 domain-containing protein -
JMW08_RS22970 () 9041..9649 - 609 Protein_9 IS66 family transposase ISEc22 Transposase
JMW08_RS22975 () 9717..10499 - 783 WP_001317493.1 IS21 family transposase IS100kyp Transposase
JMW08_RS22980 () 10496..11518 - 1023 WP_000255956.1 IS21 family transposase IS100kyp Transposase
JMW08_RS22985 () 11604..12549 - 946 Protein_12 IS66 family transposase ISEc8 Transposase
JMW08_RS22990 () 12598..12972 - 375 WP_024193849.1 IS66 family transposase ISKpn24 Transposase
JMW08_RS22995 () 12997..13701 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW08_RS23000 () 13755..14195 - 441 Protein_15 CatB-related O-acetyltransferase -
JMW08_RS23005 () 14333..15163 - 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
JMW08_RS23010 () 15294..15848 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
JMW08_RS23015 () 15992..16696 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW08_RS23020 () 16761..19004 - 2244 Protein_19 Tn3 family transposase TnpA_Tn3 Transposase
JMW08_RS23025 () 19018..19350 + 333 WP_001393253.1 WbuC family cupin fold metalloprotein -
JMW08_RS23030 () 19397..20272 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
JMW08_RS23035 () 20528..21790 - 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
JMW08_RS23040 () 21972..22157 - 186 WP_153593977.1 DUF4158 domain-containing protein -
JMW08_RS23045 () 22197..22901 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW08_RS23050 () 22959..25373 + 2415 Protein_25 Tn3 family transposase TnpA_ISSba14 Transposase
JMW08_RS23055 () 25407..25511 + 105 Protein_26 IS5/IS1182 family transposase -
JMW08_RS23060 () 25661..26293 - 633 Protein_27 histidine-type phosphatase -
JMW08_RS23065 () 26415..26900 - 486 WP_000874189.1 hypothetical protein -
JMW08_RS23070 () 26925..27410 - 486 WP_001267176.1 TlpA family protein disulfide reductase -
JMW08_RS23075 () 27397..28092 - 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
JMW08_RS23080 () 28097..29227 - 1131 WP_000729219.1 ABC transporter permease -
JMW08_RS23085 () 29217..30500 - 1284 WP_000964653.1 ABC transporter permease -
JMW08_RS23090 () 30503..31882 - 1380 WP_000119836.1 DUF2318 domain-containing protein -
JMW08_RS23095 () 31986..32513 - 528 WP_000178050.1 iron transporter -
JMW08_RS23100 () 32554..34440 - 1887 WP_000118029.1 FTR1 family iron permease -
JMW08_RS23105 () 34787..35602 - 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
JMW08_RS23110 () 35785..36291 - 507 WP_000949452.1 protein disulfide oxidoreductase -
JMW08_RS23115 () 36281..36439 - 159 WP_000449408.1 DsbA family protein -
JMW08_RS23120 () 36589..36702 - 114 Protein_39 IS6 family transposase -
JMW08_RS23125 () 36902..37599 + 698 Protein_40 IS1 family transposase IS1X2 Transposase
JMW08_RS23130 () 37614..37871 - 258 Protein_41 AraC family transcriptional regulator -
JMW08_RS23135 () 37959..38552 + 594 WP_000428546.1 tetracyline resistance-associated transcriptional repressor TetC -
JMW08_RS23140 () 38665..39870 - 1206 WP_001089068.1 Tetracycline resistance protein, class B ARG
JMW08_RS23145 () 39952..40575 + 624 WP_000088605.1 Tetracycline repressor protein class B from transposon Tn10 VF
JMW08_RS23150 () 40553..41239 - 687 WP_001284954.1 winged helix-turn-helix domain-containing protein -
JMW08_RS23155 () 41247..41633 - 387 WP_000460651.1 hypothetical protein -
JMW08_RS23160 () 41731..42428 - 698 Protein_47 IS1 family transposase IS1R Transposase
JMW08_RS23165 () 42707..43366 + 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
JMW08_RS23170 () 43567..43944 - 378 WP_000656305.1 GNAT family N-acetyltransferase -
JMW08_RS23175 () 44011..46977 - 2967 WP_001138064.1 Tn3 family transposase TnpA_TnAs3 Transposase
JMW08_RS23180 () 46980..47540 - 561 WP_021532377.1 Tn3 family transposase TnpR_TnAs3 Transposase
JMW08_RS23185 () 47591..48295 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW08_RS23190 () 48417..49322 + 906 WP_000219391.1 hypothetical protein ARG
JMW08_RS23195 () 49319..50557 + 1239 WP_000004159.1 MFS transporter -
JMW08_RS23200 () 50557..51141 + 585 WP_001137892.1 TetR family transcriptional regulator -
JMW08_RS23205 () 51634..52398 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
JMW08_RS23210 () 52516..52581 - 66 Protein_57 EAL domain-containing protein -
JMW08_RS23215 () 52625..52930 - 306 WP_000130000.1 Transcriptional regulator Relaxase
JMW08_RS23220 () 52941..54146 - 1206 WP_000184001.1 chromate efflux transporter -
JMW08_RS23225 () 54302..54505 - 204 WP_000376616.1 hypothetical protein -
JMW08_RS23230 () 54633..55472 - 840 WP_000259031.1 Dihydropteroate synthase ARG
JMW08_RS23235 () 55466..55813 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
JMW08_RS23240 () 56019..56807 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
JMW08_RS23245 () 56938..57411 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
JMW08_RS23250 () 57569..58582 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
JMW08_RS23255 () 58785..59135 + 351 WP_162861269.1 DUF3330 domain-containing protein -
JMW08_RS23260 () 59334..60038 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW08_RS23265 () 60075..61202 - 1128 WP_014837927.1 DUF3883 domain-containing protein -
JMW08_RS23270 () 61253..61480 - 228 WP_000248278.1 hypothetical protein -
JMW08_RS23275 () 61504..61695 + 192 WP_000951934.1 hypothetical protein -
JMW08_RS23280 () 62177..62719 - 543 WP_000587837.1 AAA family ATPase -
JMW08_RS23285 () 62732..63592 - 861 WP_000557454.1 SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
JMW08_RS23290 () 63735..64640 + 906 Protein_73 IS4 family transposase IS10R Transposase
JMW08_RS23295 () 64689..65393 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JMW08_RS23300 () 65635..66495 + 861 WP_000027057.1 Beta-lactamase TEM ARG
JMW08_RS23305 () 66645..66743 - 99 Protein_76 IS1 family transposase -
JMW08_RS23310 () 66772..68082 - 1311 WP_001262765.1 DUF262 domain-containing protein -
JMW08_RS23315 () 68367..68768 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
JMW08_RS23320 () 68701..68958 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
JMW08_RS23325 () 69051..69704 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
JMW08_RS23330 () 70643..71500 - 858 WP_032152935.1 incFII family plasmid replication initiator RepA -
JMW08_RS23335 () 71493..71567 - 75 WP_001365705.1 RepA leader peptide Tap -
JMW08_RS23340 () 71802..72059 - 258 WP_000083821.1 replication regulatory protein RepA -
JMW08_RS23345 () 72464..73486 + 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
JMW08_RS23350 () 73958..74311 + 354 WP_000005489.1 hypothetical protein -
JMW08_RS23355 () 74724..75302 - 579 WP_032152936.1 DUF2726 domain-containing protein -
JMW08_RS23360 () 75335..76032 + 698 Protein_87 IS1 family transposase IS1S Transposase
JMW08_RS23365 () 76141..76503 + 363 WP_059330006.1 IS66 family transposase ISEc23 Transposase
JMW08_RS23370 () 76500..76850 + 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
JMW08_RS23375 () 76881..77102 + 222 WP_000080227.1 IS66 family transposase ISEc43 Transposase
JMW08_RS23380 () 77054..77395 + 342 Protein_91 transposase -
JMW08_RS23385 () 77459..77938 - 480 WP_001496175.1 ArgR family transcriptional regulator -
JMW08_RS23390 () 78019..79422 - 1404 WP_000514417.1 YfcC family protein -
JMW08_RS23395 () 79470..80474 - 1005 WP_000154545.1 Ornithine carbamoyltransferase VF
JMW08_RS23400 () 80559..81470 - 912 WP_000440183.1 carbamate kinase -
JMW08_RS23405 () 81481..82701 - 1221 WP_000410951.1 arginine deiminase -
JMW08_RS23410 () 83594..84076 + 483 Protein_97 VENN motif pre-toxin domain-containing protein -
JMW08_RS23415 () 84022..84468 - 447 Protein_98 incFII family plasmid replication initiator RepA -
JMW08_RS23420 () 84461..84535 - 75 WP_032336874.1 RepA leader peptide Tap -
JMW08_RS23425 () 84771..85028 - 258 WP_000083833.1 replication regulatory protein RepA -
JMW08_RS23430 () 85312..85518 - 207 WP_015387399.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 85505..85566 + 62 NuclAT_2 - Antitoxin Detail
- () 85505..85566 + 62 NuclAT_2 - Antitoxin Detail
- () 85505..85566 + 62 NuclAT_2 - Antitoxin Detail
- () 85505..85566 + 62 NuclAT_2 - Antitoxin Detail
JMW08_RS23435 () 85705..85887 - 183 WP_000968309.1 hypothetical protein -
JMW08_RS23440 () 85988..86604 + 617 Protein_103 IS1 family transposase IS1G Transposase
JMW08_RS23445 () 86642..88213 - 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
JMW08_RS23450 () 88233..88580 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
JMW08_RS23455 () 88580..89257 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
JMW08_RS23460 () 89312..89401 + 90 Protein_107 IS1 family transposase -
JMW08_RS23465 () 89702..89914 - 213 WP_005012601.1 hypothetical protein -
JMW08_RS23470 () 90048..90608 - 561 WP_000139363.1 fertility inhibition protein FinO -
JMW08_RS23475 () 90663..91409 - 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
JMW08_RS23480 () 91429..96549 - 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
JMW08_RS23485 () 96549..98738 - 2190 WP_040110343.1 type IV conjugative transfer system coupling protein TraD -
JMW08_RS23490 () 98990..99721 - 732 WP_000850424.1 complement resistance protein TraT -
JMW08_RS23495 () 99735..100244 - 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
JMW08_RS23500 () 100241..101998 - 1758 Protein_115 conjugal transfer mating pair stabilization protein TraG -
JMW08_RS23505 () 102041..103576 - 1536 WP_001333339.1 IS66 family transposase ISEc22 Transposase
JMW08_RS23510 () 103625..103972 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
JMW08_RS23515 () 103969..104373 - 405 WP_000839179.1 IS66 family transposase ISEc22 Transposase
JMW08_RS23520 () 104453..105529 - 1077 Protein_119 conjugal transfer mating pair stabilization protein TraG -
JMW08_RS23525 () 105526..106899 - 1374 WP_021518370.1 conjugal transfer protein TraH -
JMW08_RS23530 () 106886..107278 - 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
JMW08_RS23535 () 107232..107606 - 375 WP_071788165.1 P-type conjugative transfer protein TrbJ -
JMW08_RS23540 () 107536..108090 - 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
JMW08_RS23545 () 108077..108361 - 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
JMW08_RS23550 () 108442..108777 + 336 WP_000415571.1 hypothetical protein -
JMW08_RS23555 () 108932..109678 - 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
JMW08_RS23560 () 109693..111234 - 1542 WP_002431311.1 IS21 family transposase ISEc12 Transposase
JMW08_RS23565 () 111699..112442 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
JMW08_RS23570 () 112435..112692 - 258 WP_000864312.1 conjugal transfer protein TrbE -
JMW08_RS23575 () 112719..114527 - 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
JMW08_RS23580 () 114524..115162 - 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
JMW08_RS23585 () 115171..116163 - 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
JMW08_RS23590 () 116160..116792 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
JMW08_RS23595 () 116789..117175 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
JMW08_RS23600 () 117172..119799 - 2628 WP_001064245.1 type IV secretion system protein TraC -
JMW08_RS23605 () 119959..120180 - 222 WP_001278689.1 conjugal transfer protein TraR -
JMW08_RS23610 () 120315..120830 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
JMW08_RS23615 () 120827..121078 - 252 WP_001038342.1 conjugal transfer protein TrbG -
JMW08_RS23620 () 121090..121320 - 231 WP_001352845.1 conjugal transfer protein TrbD -
JMW08_RS23625 () 121274..121864 - 591 WP_000002787.1 conjugal transfer protein TraP -
JMW08_RS23630 () 121854..123281 - 1428 WP_000146685.1 conjugal transfer protein TraB -
JMW08_RS23635 () 123281..123985 - 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
JMW08_RS23640 () 123996..124562 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
JMW08_RS23645 () 124584..124895 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
JMW08_RS23650 () 124910..125275 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
JMW08_RS23655 () 125308..125703 - 396 WP_001309237.1 conjugal transfer relaxosome protein TraY -
JMW08_RS23660 () 125802..126491 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
JMW08_RS23665 () 126678..127061 - 384 WP_001151524.1 relaxosome protein TraM -
JMW08_RS23670 () 127382..127984 + 603 WP_013362798.1 hypothetical protein VF
JMW08_RS23675 () 128281..129102 - 822 WP_001234426.1 DUF945 domain-containing protein -
JMW08_RS23680 () 129220..129507 - 288 WP_000107535.1 hypothetical protein -
JMW08_RS23685 () 130428..130586 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 130630..130661 - 32 NuclAT_1 - Antitoxin Detail
- () 130630..130661 - 32 NuclAT_1 - Antitoxin Detail
- () 130630..130661 - 32 NuclAT_1 - Antitoxin Detail
- () 130630..130661 - 32 NuclAT_1 - Antitoxin Detail
- () 132103..132300 - 198 NuclAT_0 - -
- () 132103..132300 - 198 NuclAT_0 - -
- () 132103..132300 - 198 NuclAT_0 - -
- () 132103..132300 - 198 NuclAT_0 - -
JMW08_RS23695 () 132112..132300 + 189 WP_001299721.1 hypothetical protein -
JMW08_RS23700 () 132312..133031 - 720 WP_001276238.1 plasmid SOS inhibition protein A -
JMW08_RS23705 () 133028..133462 - 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
JMW08_RS23710 () 133517..133714 - 198 Protein_157 hypothetical protein -
JMW08_RS23715 () 133742..133975 - 234 WP_000005990.1 DUF905 family protein -
JMW08_RS23720 () 134043..134582 - 540 WP_000290840.1 single-stranded DNA-binding protein -
JMW08_RS23725 () 134608..134814 - 207 WP_000275856.1 hypothetical protein -
JMW08_RS23730 () 135224..135424 - 201 WP_025492130.1 hypothetical protein -
JMW08_RS23735 () 135450..136015 - 566 Protein_162 class I SAM-dependent methyltransferase -
JMW08_RS23740 () 136063..137424 - 1362 WP_000199439.1 DUF3560 domain-containing protein -
JMW08_RS23745 () 137476..137706 - 231 WP_000218642.1 hypothetical protein -
JMW08_RS23750 () 138218..138466 + 249 WP_155105262.1 hypothetical protein -
JMW08_RS23755 () 138738..138929 - 192 WP_001027495.1 hypothetical protein -
JMW08_RS23760 () 138926..139348 - 423 WP_000271685.1 DUF1380 family protein -
JMW08_RS23765 () 139395..139697 - 303 WP_001666994.1 antirestriction protein -
JMW08_RS23770 () 140234..141004 - 771 WP_001006251.1 hypothetical protein -
JMW08_RS23775 () 141049..141483 - 435 WP_001546462.1 DUF1380 family protein -
JMW08_RS23780 () 141497..141718 - 222 WP_001104873.1 hypothetical protein -
JMW08_RS23785 () 141719..142402 - 684 WP_032181561.1 DNA methylase -
JMW08_RS23790 () 142479..142783 - 305 Protein_173 hypothetical protein -
JMW08_RS23795 () 142787..143689 - 903 WP_064766247.1 DUF1281 domain-containing protein -
JMW08_RS23800 () 144427..145398 - 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
JMW08_RS23805 () 145398..146564 - 1167 WP_000772446.1 hypothetical protein VF
JMW08_RS23810 () 147152..147907 - 756 WP_000852146.1 replication initiation protein RepE -
JMW08_RS23815 () 148629..149435 - 807 WP_000016970.1 site-specific integrase -
JMW08_RS23820 () 149436..149741 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
JMW08_RS23825 () 149743..149961 - 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA -
JMW08_RS23830 () 150521..150751 + 231 WP_001261286.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
JMW08_RS23835 () 150748..151164 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
JMW08_RS23840 () 151239..152804 + 1566 WP_001128474.1 AAA family ATPase -
JMW08_RS23845 () 152789..153811 + 1023 WP_000361402.1 helicase UvrD -
JMW08_RS23850 () 154065..154751 - 687 Protein_185 IS1 family transposase IS1S Transposase
JMW08_RS23855 () 155277..157478 - 2202 WP_000973519.1 Ferric aerobactin receptor VF
JMW08_RS23860 () 157560..158837 - 1278 WP_000750130.1 L-lysine N6-monooxygenase VF
JMW08_RS23865 () 158834..160576 - 1743 WP_001015721.1 Aerobactin synthase VF
JMW08_RS23870 () 160576..161523 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
JMW08_RS23875 () 161524..163248 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
JMW08_RS23880 () 163384..164577 + 1194 WP_000095526.1 MFS transporter -
JMW08_RS23885 () 164957..165337 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
JMW08_RS23890 () 165438..166135 - 698 Protein_193 IS1 family transposase IS1G Transposase
JMW08_RS23895 () 166455..166868 - 414 Protein_194 phosphopyruvate hydratase -
JMW08_RS23900 () 166866..167123 + 258 Protein_195 Tn3 family transposase -
JMW08_RS23905 () 167357..168214 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
JMW08_RS23910 () 168211..169068 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
JMW08_RS23915 () 169065..169892 - 828 WP_000983710.1 Manganese transport system ATP-binding protein MntB VF
JMW08_RS23920 () 169892..170806 - 915 WP_000949005.1 putative periplasmic iron-binding protein VF
JMW08_RS23925 () 171162..171859 + 698 Protein_200 IS1 family transposase IS1G Transposase
JMW08_RS23930 () 172039..172552 - 514 Protein_201 DUF4113 domain-containing protein -
JMW08_RS23935 () 172613..172717 - 105 Protein_202 AAA family ATPase -
JMW08_RS23940 () 172719..173042 - 324 Protein_203 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance