MGE detailed information
MGE type: Conjugative plasmid MGE length: 112588 bp
Accession: NZ_LR130546 Location: 1..112588 Organism: Escherichia coli strain B36 isolate B36 Replicon: plasmid 2
Accession: NZ_LR130546 Location: 1..112588 Organism: Escherichia coli strain B36 isolate B36 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EW036_RS25730 () | 1..756 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| EW036_RS25735 () | 1344..2510 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| EW036_RS25740 () | 2510..3481 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| EW036_RS25755 () | 4348..5250 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| EW036_RS25760 () | 5254..5558 | + | 305 | Protein_4 | hypothetical protein | - |
| EW036_RS25765 () | 5635..6318 | + | 684 | WP_000086185.1 | DNA methylase | - |
| EW036_RS25770 () | 6319..6540 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| EW036_RS25775 () | 6554..6988 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| EW036_RS25780 () | 7039..7815 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| EW036_RS25790 () | 8355..8657 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| EW036_RS25795 () | 8704..9126 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| EW036_RS25800 () | 9123..9314 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| EW036_RS25810 () | 10349..10579 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| EW036_RS25815 () | 10631..11992 | + | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| EW036_RS25820 () | 12039..12602 | + | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| EW036_RS25850 () | 14118..16019 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| EW036_RS25855 () | 16169..16654 | + | 486 | WP_042029316.1 | single-stranded DNA-binding protein | - |
| EW036_RS25860 () | 16710..16943 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| EW036_RS25865 () | 17002..18960 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| EW036_RS25870 () | 19015..19449 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| EW036_RS25875 () | 19446..20165 | + | 720 | WP_001276234.1 | plasmid SOS inhibition protein A | - |
| EW036_RS26685 () | 20177..20365 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 20177..20401 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 20177..20401 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 20177..20401 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 20177..20401 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| EW036_RS25880 () | 20445..20603 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| EW036_RS25905 () | 21522..21809 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| EW036_RS25910 () | 21930..22751 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| EW036_RS25915 () | 23048..23695 | - | 648 | WP_000614282.1 | hypothetical protein | VF |
| EW036_RS25920 () | 23981..24364 | + | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| EW036_RS25925 () | 24558..25244 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| EW036_RS25930 () | 25338..25565 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| EW036_RS25935 () | 25599..25961 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| EW036_RS25940 () | 25966..26277 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| EW036_RS25945 () | 26299..26865 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| EW036_RS25950 () | 26876..27580 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| EW036_RS25955 () | 27580..29007 | + | 1428 | WP_000146638.1 | conjugal transfer protein TraB | - |
| EW036_RS25960 () | 28997..29581 | + | 585 | WP_000002795.1 | conjugal transfer protein TraP | - |
| EW036_RS25965 () | 29535..29888 | + | 354 | WP_071528018.1 | conjugal transfer protein TrbD | - |
| EW036_RS25970 () | 29881..30132 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| EW036_RS25975 () | 30129..30644 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EW036_RS25980 () | 30779..31000 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| EW036_RS25985 () | 31160..32785 | + | 1626 | Protein_39 | TraC family protein | - |
| EW036_RS25990 () | 32838..33542 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| EW036_RS25995 () | 33607..34293 | + | 687 | Protein_41 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| EW036_RS26000 () | 34430..34831 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EW036_RS26005 () | 34764..35021 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EW036_RS26010 () | 35114..35767 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EW036_RS26020 () | 36706..37563 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| EW036_RS26025 () | 37556..37630 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| EW036_RS26035 () | 37868..38122 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| EW036_RS26040 () | 38362..38952 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| EW036_RS26045 () | 39022..39719 | - | 698 | Protein_49 | IS1 family transposase IS1R | Transposase |
| EW036_RS26050 () | 39999..40211 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| EW036_RS26055 () | 40340..40900 | - | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| EW036_RS26060 () | 41003..41797 | - | 795 | Protein_52 | alpha/beta fold hydrolase | - |
| EW036_RS26065 () | 41862..42566 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| EW036_RS26070 () | 42620..44836 | - | 2217 | Protein_54 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| EW036_RS26075 () | 44931..45536 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| EW036_RS26080 () | 45560..46309 | - | 750 | Protein_56 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EW036_RS26085 () | 46298..46705 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| EW036_RS26090 () | 46843..47727 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| EW036_RS26095 () | 47759..48958 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| EW036_RS26100 () | 49064..49714 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| EW036_RS26105 () | 49746..49988 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| EW036_RS26110 () | 50030..51544 | - | 1515 | Protein_62 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EW036_RS26115 () | 51610..52314 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW036_RS26690 () | 52355..52534 | - | 180 | Protein_64 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| EW036_RS26125 () | 52660..53010 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| EW036_RS26135 () | 53213..54145 | - | 933 | WP_129685279.1 | Tyrosine recombinase XerC | VF |
| EW036_RS26140 () | 54303..54776 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| EW036_RS26145 () | 54907..55695 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| EW036_RS26150 () | 55901..56248 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| EW036_RS26155 () | 56242..57081 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| EW036_RS26165 () | 57209..57412 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| EW036_RS26170 () | 57568..58773 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| EW036_RS26175 () | 58784..59089 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| EW036_RS26695 () | 59133..59198 | + | 66 | Protein_74 | EAL domain-containing protein | - |
| EW036_RS26185 () | 59316..60080 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| EW036_RS26200 () | 60573..61157 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| EW036_RS26205 () | 61157..62395 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| EW036_RS26210 () | 62392..63297 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| EW036_RS26220 () | 63419..64123 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW036_RS26225 () | 64259..65134 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| EW036_RS26230 () | 65181..65513 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| EW036_RS26235 () | 65527..67770 | + | 2244 | Protein_82 | Tn3 family transposase TnpA_Tn3 | Transposase |
| EW036_RS26240 () | 67835..68539 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW036_RS26245 () | 68593..69033 | - | 441 | Protein_84 | CatB-related O-acetyltransferase | - |
| EW036_RS26250 () | 69171..70001 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| EW036_RS26255 () | 70132..70686 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| EW036_RS26260 () | 70830..71534 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW036_RS26265 () | 71760..72575 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| EW036_RS26275 () | 72922..74808 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| EW036_RS26280 () | 74849..75376 | + | 528 | WP_000178050.1 | iron transporter | - |
| EW036_RS26285 () | 75480..76859 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| EW036_RS26290 () | 76862..78145 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| EW036_RS26295 () | 78135..79265 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| EW036_RS26300 () | 79270..79965 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| EW036_RS26305 () | 79952..80437 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| EW036_RS26310 () | 80462..80947 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| EW036_RS26315 () | 81069..81599 | + | 531 | Protein_97 | histidine-type phosphatase | - |
| EW036_RS26320 () | 81657..82361 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW036_RS26325 () | 82386..83582 | + | 1197 | Protein_99 | IS3 family transposase | - |
| EW036_RS26330 () | 83604..83837 | + | 234 | Protein_100 | Tn3 family transposase | - |
| EW036_RS26335 () | 83914..84222 | + | 309 | Protein_101 | IS4 family transposase ISEc13 | Transposase |
| EW036_RS26340 () | 84281..85591 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| EW036_RS26345 () | 85584..86657 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| EW036_RS26350 () | 86663..87487 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| EW036_RS26355 () | 87498..88385 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| EW036_RS26360 () | 88375..89253 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| EW036_RS26365 () | 89384..89824 | - | 441 | Protein_107 | zinc-binding dehydrogenase | - |
| EW036_RS26375 () | 90225..91115 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| EW036_RS26380 () | 91140..91520 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| EW036_RS26385 () | 91553..92518 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| EW036_RS26390 () | 92564..93316 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| EW036_RS26395 () | 93921..94205 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| EW036_RS26400 () | 94205..94480 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| EW036_RS26405 () | 94586..94867 | + | 282 | WP_129685282.1 | hypothetical protein | - |
| EW036_RS26410 () | 94896..95593 | + | 698 | Protein_115 | IS1 family transposase IS1S | Transposase |
| EW036_RS26415 () | 95847..96869 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| EW036_RS26420 () | 96854..98419 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| EW036_RS26425 () | 98494..98910 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EW036_RS26430 () | 98907..99137 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EW036_RS26435 () | 99518..103312 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| EW036_RS26440 () | 103357..103773 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EW036_RS26445 () | 103770..104000 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EW036_RS26450 () | 104265..104765 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| EW036_RS26455 () | 104778..105551 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| EW036_RS26460 () | 105762..107375 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| EW036_RS26465 () | 107406..107756 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| EW036_RS26470 () | 107753..108178 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| EW036_RS26475 () | 108240..109391 | + | 1152 | WP_031325939.1 | DUF3800 domain-containing protein | - |
| EW036_RS26480 () | 109425..109937 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| EW036_RS26485 () | 110483..110701 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| EW036_RS26490 () | 110703..111008 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | - |
| EW036_RS26495 () | 111009..111815 | + | 807 | WP_000016982.1 | site-specific integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|