MGE detailed information
MGE type: Conjugative plasmid MGE length: 135602 bp
Accession: NZ_HG941719 Location: 1..135602 Organism: Escherichia coli O25b:H4-ST131 strain EC958 Replicon: plasmid pEC958
Accession: NZ_HG941719 Location: 1..135602 Organism: Escherichia coli O25b:H4-ST131 strain EC958 Replicon: plasmid pEC958
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EC958_RS25595 () | 408..626 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| EC958_RS25600 () | 628..933 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| EC958_RS25605 () | 934..1740 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| EC958_RS25610 () | 2514..3269 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| EC958_RS25615 () | 3857..5023 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| EC958_RS25620 () | 5023..5994 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| EC958_RS25625 () | 6861..7763 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| EC958_RS28990 () | 7767..8071 | + | 305 | Protein_7 | hypothetical protein | - |
| EC958_RS25635 () | 8148..8831 | + | 684 | WP_000086185.1 | DNA methylase | - |
| EC958_RS25640 () | 8832..9053 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| EC958_RS25645 () | 9067..9501 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| EC958_RS29465 () | 9552..10328 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| EC958_RS25655 () | 10868..11170 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| EC958_RS25660 () | 11217..11639 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| EC958_RS25665 () | 11636..11827 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| EC958_RS25670 () | 12862..13092 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| EC958_RS25675 () | 13144..14505 | + | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| EC958_RS25680 () | 14552..15115 | + | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| EC958_RS25700 () | 16631..18532 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| EC958_RS25705 () | 18682..19167 | + | 486 | WP_042029316.1 | single-stranded DNA-binding protein | - |
| EC958_RS25710 () | 19223..19456 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| EC958_RS25715 () | 19515..21473 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| EC958_RS25720 () | 21528..21962 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| EC958_RS25725 () | 21959..22678 | + | 720 | WP_001276234.1 | plasmid SOS inhibition protein A | - |
| EC958_RS29470 () | 22690..22878 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 22690..22914 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 22690..22914 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 22690..22914 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 22690..22914 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| EC958_RS25735 () | 22958..23116 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| EC958_RS25745 () | 24035..24322 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| EC958_RS25750 () | 24443..25264 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| EC958_RS25755 () | 25563..26210 | - | 648 | WP_000614282.1 | hypothetical protein | VF |
| EC958_RS25760 () | 26496..26879 | + | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| EC958_RS25765 () | 27073..27759 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| EC958_RS25770 () | 27853..28080 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| EC958_RS25775 () | 28114..28476 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| EC958_RS25780 () | 28481..28792 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| EC958_RS25785 () | 28814..29380 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| EC958_RS25790 () | 29391..30095 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| EC958_RS25795 () | 30095..31522 | + | 1428 | WP_000146638.1 | conjugal transfer protein TraB | - |
| EC958_RS25800 () | 31512..32096 | + | 585 | WP_000002795.1 | conjugal transfer protein TraP | - |
| EC958_RS25805 () | 32050..32403 | + | 354 | WP_071528018.1 | conjugal transfer protein TrbD | - |
| EC958_RS25810 () | 32396..32647 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| EC958_RS25815 () | 32644..33159 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EC958_RS28350 () | 33294..33515 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| EC958_RS25825 () | 33675..36305 | + | 2631 | WP_012783967.1 | type IV secretion system protein TraC | - |
| EC958_RS25830 () | 36352..37056 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS25840 () | 37300..38562 | - | 1263 | WP_000608641.1 | IS1380 family transposase ISEcp1 | Transposase |
| EC958_RS29475 () | 38768..38962 | - | 195 | Protein_45 | Tn3 family transposase TnpA_Tn3 | Transposase |
| EC958_RS25850 () | 39126..39683 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EC958_RS25855 () | 39866..40726 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EC958_RS25860 () | 40873..43344 | - | 2472 | Protein_48 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| EC958_RS29480 () | 43347..43433 | - | 87 | Protein_49 | helix-turn-helix domain-containing protein | - |
| EC958_RS25865 () | 43487..44191 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| EC958_RS25870 () | 44307..44612 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| EC958_RS25875 () | 44621..45259 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EC958_RS25880 () | 45256..47106 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EC958_RS25885 () | 47133..47390 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| EC958_RS25890 () | 47383..48126 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EC958_RS25895 () | 48140..48484 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| EC958_RS25900 () | 48603..48887 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EC958_RS25905 () | 48874..49419 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EC958_RS25910 () | 49349..49696 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| EC958_RS25915 () | 49644..50069 | + | 426 | WP_001444237.1 | F-type conjugal transfer protein TrbF | - |
| EC958_RS25920 () | 50056..51429 | + | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| EC958_RS25925 () | 51426..54248 | + | 2823 | WP_001007039.1 | conjugal transfer mating pair stabilization protein TraG | - |
| EC958_RS25930 () | 54264..54749 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| EC958_RS25935 () | 54798..55529 | + | 732 | WP_000782451.1 | complement resistance protein TraT | - |
| EC958_RS25940 () | 55732..56469 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| EC958_RS25945 () | 56520..58718 | + | 2199 | WP_000009332.1 | type IV conjugative transfer system coupling protein TraD | - |
| EC958_RS25950 () | 58718..63988 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| EC958_RS25955 () | 64008..64754 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| EC958_RS25960 () | 64813..65673 | + | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| EC958_RS25965 () | 65776..66336 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| EC958_RS25970 () | 66465..66677 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| EC958_RS25975 () | 66957..67654 | + | 698 | Protein_72 | IS1 family transposase IS1R | Transposase |
| EC958_RS25980 () | 67699..68160 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| EC958_RS25985 () | 68206..68415 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| EC958_RS25990 () | 68453..69043 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| EC958_RS25995 () | 69283..69537 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| EC958_RS26000 () | 69775..69849 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| EC958_RS26005 () | 69842..70699 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| EC958_RS26010 () | 71638..72291 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EC958_RS29485 () | 72384..72641 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EC958_RS26020 () | 72574..72975 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EC958_RS26025 () | 73112..75316 | - | 2205 | Protein_82 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| EC958_RS26030 () | 75380..76084 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS26035 () | 76142..76672 | - | 531 | Protein_84 | histidine-type phosphatase | - |
| EC958_RS26040 () | 76794..77279 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| EC958_RS26045 () | 77304..77789 | - | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| EC958_RS26050 () | 77776..78471 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| EC958_RS26055 () | 78476..79606 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| EC958_RS26060 () | 79596..80879 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| EC958_RS26065 () | 80882..82261 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| EC958_RS26070 () | 82365..82892 | - | 528 | WP_000178050.1 | iron transporter | - |
| EC958_RS26075 () | 82933..84819 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| EC958_RS26080 () | 85166..85981 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| EC958_RS26085 () | 86207..86911 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS29660 () | 86952..87131 | - | 180 | Protein_95 | recombinase family protein | - |
| EC958_RS29490 () | 87257..87607 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| EC958_RS26100 () | 87810..88823 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| EC958_RS26105 () | 88981..89454 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| EC958_RS26110 () | 89585..90373 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| EC958_RS26115 () | 90579..90926 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| EC958_RS26120 () | 90920..91759 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| EC958_RS26125 () | 91887..92090 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| EC958_RS26130 () | 92246..93451 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| EC958_RS26135 () | 93462..93767 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| EC958_RS29565 () | 93811..93876 | + | 66 | Protein_105 | EAL domain-containing protein | - |
| EC958_RS26140 () | 93994..94758 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| EC958_RS26150 () | 95251..95835 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| EC958_RS26155 () | 95835..97073 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| EC958_RS26160 () | 97070..97975 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| EC958_RS26165 () | 98097..98801 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS26170 () | 98937..99812 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| EC958_RS26175 () | 99859..100191 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| EC958_RS26180 () | 100205..102448 | + | 2244 | Protein_113 | Tn3 family transposase TnpA_Tn3 | Transposase |
| EC958_RS26185 () | 102513..103217 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS26485 () | 103271..103711 | - | 441 | Protein_115 | CatB-related O-acetyltransferase | - |
| EC958_RS26190 () | 103849..104679 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| EC958_RS26195 () | 104810..105364 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| EC958_RS26200 () | 105508..106212 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS26205 () | 106278..107792 | + | 1515 | Protein_119 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EC958_RS26210 () | 107834..108076 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| EC958_RS26215 () | 108108..108758 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| EC958_RS26220 () | 108864..110063 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| EC958_RS26225 () | 110095..110979 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| EC958_RS26230 () | 111117..111524 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| EC958_RS26235 () | 111513..112262 | + | 750 | Protein_125 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EC958_RS26240 () | 112286..112891 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| EC958_RS26245 () | 112986..113687 | + | 702 | Protein_127 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| EC958_RS26250 () | 113739..114443 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EC958_RS29665 () | 114506..114610 | + | 105 | Protein_129 | RidA family protein | - |
| EC958_RS26255 () | 114643..115608 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| EC958_RS26260 () | 115654..116406 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| EC958_RS26265 () | 117011..117295 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| EC958_RS26270 () | 117295..117570 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| EC958_RS26275 () | 117676..117969 | + | 294 | WP_001105060.1 | hypothetical protein | - |
| EC958_RS29495 () | 118004..118132 | - | 129 | Protein_135 | IS481 family transposase | - |
| EC958_RS26280 () | 118165..119334 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| EC958_RS26290 () | 119827..120134 | + | 308 | Protein_137 | type II toxin-antitoxin system ParD family antitoxin | - |
| EC958_RS26295 () | 120423..121120 | + | 698 | Protein_138 | IS1 family transposase IS1S | Transposase |
| EC958_RS26300 () | 121374..122396 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| EC958_RS26305 () | 122381..123946 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| EC958_RS26310 () | 124021..124437 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EC958_RS26315 () | 124434..124664 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EC958_RS26320 () | 125045..128839 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| EC958_RS26325 () | 128884..129300 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EC958_RS26330 () | 129297..129527 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EC958_RS26335 () | 129792..130292 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| EC958_RS26340 () | 130305..131078 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| EC958_RS26345 () | 131289..132902 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| EC958_RS26350 () | 132933..133283 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| EC958_RS26355 () | 133280..133705 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| EC958_RS26360 () | 133767..134918 | + | 1152 | WP_031325939.1 | DUF3800 domain-containing protein | - |
| EC958_RS26365 () | 134952..135464 | - | 513 | WP_000151784.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|