MGE detailed information
MGE type: Conjugative plasmid MGE length: 122596 bp
Accession: NZ_CP123238 Location: 1..122596 Organism: Escherichia coli strain 4588 Replicon: plasmid pMB7355_1
Accession: NZ_CP123238 Location: 1..122596 Organism: Escherichia coli strain 4588 Replicon: plasmid pMB7355_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QET42_RS23295 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| QET42_RS23300 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| QET42_RS23305 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| QET42_RS23310 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| QET42_RS23315 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| QET42_RS23320 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| QET42_RS23325 (6256) | 6256..6645 | + | 390 | WP_001332050.1 | outer membrane protease | - |
| QET42_RS23330 (7449) | 7449..7628 | - | 180 | Protein_7 | integrase core domain-containing protein | - |
| QET42_RS23335 (7767) | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| QET42_RS23340 (9128) | 9128..9396 | - | 269 | Protein_9 | IS3 family transposase ISLad1 | Transposase |
| QET42_RS23345 (9453) | 9453..10150 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| QET42_RS23350 (10167) | 10167..10364 | - | 198 | Protein_11 | colicin V | - |
| QET42_RS23355 (10342) | 10342..10578 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| QET42_RS23360 (11120) | 11120..11323 | - | 204 | Protein_13 | hypothetical protein | - |
| QET42_RS23365 (11496) | 11496..11663 | + | 168 | Protein_14 | colicin-B | - |
| QET42_RS23370 (11681) | 11681..12208 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| QET42_RS23375 (12452) | 12452..13267 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| QET42_RS23380 (13317) | 13317..13670 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| QET42_RS23385 (13848) | 13848..14639 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| QET42_RS23390 (14636) | 14636..15325 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| QET42_RS23395 (15369) | 15369..15719 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| QET42_RS23400 (16264) | 16264..17352 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| QET42_RS23405 (17354) | 17354..19579 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| QET42_RS23410 (19629) | 19629..20528 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| QET42_RS23415 (20518) | 20518..20808 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| QET42_RS23420 (21104) | 21104..21334 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| QET42_RS23425 (21331) | 21331..21747 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QET42_RS23430 (21909) | 21909..24047 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| QET42_RS23435 (24401) | 24401..24658 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| QET42_RS23440 (24658) | 24658..25248 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| QET42_RS23445 (25511) | 25511..26971 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
| QET42_RS23450 (27259) | 27259..27876 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| QET42_RS23455 (28274) | 28274..29536 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| QET42_RS23460 (29792) | 29792..30667 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| QET42_RS23465 (30714) | 30714..31007 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| QET42_RS23470 (31224) | 31224..32303 | - | 1080 | WP_001089727.1 | permease | - |
| QET42_RS23475 (32408) | 32408..32731 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| QET42_RS23480 (32892) | 32892..33212 | + | 321 | Protein_37 | NAD(P)H-dependent oxidoreductase | - |
| QET42_RS23485 (33265) | 33265..33969 | - | 705 | WP_001067834.1 | IS6-like element IS26 family transposase | - |
| QET42_RS23490 (34046) | 34046..36346 | - | 2301 | Protein_39 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QET42_RS23495 (36393) | 36393..37097 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QET42_RS23500 (37162) | 37162..37668 | + | 507 | Protein_41 | transposase | - |
| QET42_RS23505 (38085) | 38085..38975 | + | 891 | WP_223151485.1 | alpha/beta fold putative hydrolase EstX | - |
| QET42_RS23510 (39064) | 39064..39902 | + | 839 | Protein_43 | Streptomycin 3''-adenylyltransferase | ARG |
| QET42_RS23515 (40025) | 40025..40357 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| QET42_RS23520 (40604) | 40604..41236 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| QET42_RS23525 (41259) | 41259..41534 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| QET42_RS23530 (41537) | 41537..42328 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| QET42_RS23535 (42797) | 42797..43042 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| QET42_RS23540 (43080) | 43080..43943 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| QET42_RS23545 (44089) | 44089..44346 | - | 258 | Protein_50 | hypothetical protein | - |
| QET42_RS23550 (44401) | 44401..45105 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QET42_RS23555 (45258) | 45258..46079 | - | 822 | WP_000939727.1 | hypothetical protein | ARG |
| QET42_RS23560 (46164) | 46164..47002 | - | 839 | Protein_53 | Streptomycin 3''-adenylyltransferase | ARG |
| QET42_RS23565 (47151) | 47151..47948 | + | 798 | Protein_54 | IS91 family transposase ISAzo26 | Transposase |
| QET42_RS23570 (48001) | 48001..48573 | - | 573 | WP_135687074.1 | IS6 family transposase | - |
| QET42_RS23575 (48691) | 48691..48819 | - | 129 | WP_268086986.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QET42_RS23580 (48983) | 48983..49540 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QET42_RS23585 (49723) | 49723..49881 | + | 159 | Protein_58 | IS6 family transposase IS15 | Transposase |
| QET42_RS23590 (49908) | 49908..50612 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QET42_RS23595 (50678) | 50678..51223 | + | 546 | Protein_60 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QET42_RS23600 (51259) | 51259..51674 | - | 416 | Protein_61 | IS1-like element IS1B family transposase | - |
| QET42_RS23605 (51923) | 51923..52324 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| QET42_RS23610 (52257) | 52257..52514 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| QET42_RS23615 (52607) | 52607..53260 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| QET42_RS23620 (54199) | 54199..55056 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| QET42_RS23625 (55049) | 55049..55531 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| QET42_RS23630 (55524) | 55524..55571 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| QET42_RS23635 (55562) | 55562..55813 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| QET42_RS23640 (55830) | 55830..56087 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| QET42_RS23645 (56371) | 56371..56520 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56564) | 56564..56625 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56564) | 56564..56625 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56564) | 56564..56625 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56564) | 56564..56625 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| QET42_RS23650 (56881) | 56881..56955 | - | 75 | Protein_71 | endonuclease | - |
| QET42_RS23655 (57201) | 57201..57413 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| QET42_RS23660 (57549) | 57549..58109 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| QET42_RS23665 (58212) | 58212..59072 | - | 861 | WP_000704513.1 | Quorum-quenching protein AidA | VF |
| QET42_RS23670 (59131) | 59131..59877 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| QET42_RS23675 (59897) | 59897..65167 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| QET42_RS23680 (65249) | 65249..65476 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| QET42_RS23685 (65476) | 65476..65874 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QET42_RS23690 (65883) | 65883..68036 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| QET42_RS23695 (68289) | 68289..69020 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| QET42_RS23700 (69052) | 69052..69549 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| QET42_RS23705 (69565) | 69565..72387 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| QET42_RS23710 (72384) | 72384..73757 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| QET42_RS23715 (73757) | 73757..74137 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| QET42_RS23720 (74124) | 74124..74465 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| QET42_RS23725 (74395) | 74395..74940 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| QET42_RS23730 (74927) | 74927..75211 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| QET42_RS23735 (75292) | 75292..75606 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| QET42_RS23740 (75608) | 75608..75955 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| QET42_RS23745 (75971) | 75971..76714 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| QET42_RS23750 (76707) | 76707..76964 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| QET42_RS23755 (76991) | 76991..78799 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| QET42_RS23760 (78796) | 78796..79434 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| QET42_RS23765 (79443) | 79443..80435 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| QET42_RS23770 (80432) | 80432..81064 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| QET42_RS23775 (81061) | 81061..81447 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| QET42_RS23780 (81444) | 81444..82256 | - | 813 | Protein_97 | hypothetical protein | - |
| QET42_RS23785 (82339) | 82339..82743 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| QET42_RS23790 (82740) | 82740..83087 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| QET42_RS23795 (83136) | 83136..84675 | + | 1540 | Protein_100 | IS66-like element ISEc22 family transposase | - |
| QET42_RS23800 (84711) | 84711..86534 | - | 1824 | Protein_101 | type IV secretion system protein TraC | - |
| QET42_RS23805 (86694) | 86694..86915 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| QET42_RS23810 (87050) | 87050..87565 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| QET42_RS23815 (87562) | 87562..87813 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| QET42_RS23820 (87825) | 87825..88016 | - | 192 | WP_032072783.1 | conjugal transfer protein TrbD | - |
| QET42_RS23825 (88009) | 88009..88599 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| QET42_RS23830 (88589) | 88589..90016 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| QET42_RS23835 (90016) | 90016..90744 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| QET42_RS23840 (90731) | 90731..91297 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| QET42_RS23845 (91319) | 91319..91630 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| QET42_RS23850 (91645) | 91645..92010 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| QET42_RS23855 (92043) | 92043..92444 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| QET42_RS23860 (92537) | 92537..93226 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| QET42_RS23865 (93413) | 93413..93796 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QET42_RS23870 (94129) | 94129..94719 | + | 591 | WP_186235717.1 | hypothetical protein | VF |
| QET42_RS23875 (95016) | 95016..95837 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| QET42_RS23880 (95956) | 95956..96243 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| QET42_RS23885 (96268) | 96268..96474 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| QET42_RS23890 (96544) | 96544..96717 | + | 174 | Protein_119 | hypothetical protein | - |
| QET42_RS23895 (96715) | 96715..96945 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| QET42_RS23900 (97165) | 97165..97290 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| QET42_RS23905 (97232) | 97232..97381 | - | 150 | Protein_122 | plasmid maintenance protein Mok | - |
| - (97367) | 97367..97591 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (97367) | 97367..97591 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (97367) | 97367..97591 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (97367) | 97367..97591 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| QET42_RS23910 (97403) | 97403..97591 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| QET42_RS23915 (97560) | 97560..98322 | - | 763 | Protein_124 | plasmid SOS inhibition protein A | - |
| QET42_RS23920 (98319) | 98319..98753 | - | 435 | WP_064770609.1 | conjugation system SOS inhibitor PsiB | - |
| QET42_RS23925 (98808) | 98808..99005 | - | 198 | Protein_126 | hypothetical protein | - |
| QET42_RS23930 (99033) | 99033..99266 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| QET42_RS23935 (99334) | 99334..99873 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| QET42_RS23940 (99899) | 99899..100105 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| QET42_RS23945 (100175) | 100175..100255 | + | 81 | Protein_130 | hypothetical protein | - |
| QET42_RS23950 (100438) | 100438..100607 | - | 170 | Protein_131 | hypothetical protein | - |
| QET42_RS23955 (101244) | 101244..102215 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| QET42_RS23960 (102215) | 102215..103381 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| QET42_RS23970 (104863) | 104863..107064 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| QET42_RS23975 (107090) | 107090..108423 | - | 1334 | Protein_136 | L-lysine N6-monooxygenase | VF |
| QET42_RS23980 (108420) | 108420..110162 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| QET42_RS23985 (110162) | 110162..111109 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| QET42_RS23990 (111110) | 111110..112834 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| QET42_RS23995 (112970) | 112970..114163 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| QET42_RS24000 (114543) | 114543..114923 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| QET42_RS24005 (115264) | 115264..115677 | - | 414 | Protein_142 | phosphopyruvate hydratase | - |
| QET42_RS24010 (115675) | 115675..115932 | + | 258 | Protein_143 | Tn3 family transposase | - |
| QET42_RS24015 (116166) | 116166..117023 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| QET42_RS24020 (117020) | 117020..117877 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| QET42_RS24025 (117874) | 117874..118701 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| QET42_RS24030 (118701) | 118701..119615 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| QET42_RS24035 (119971) | 119971..120668 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| QET42_RS24040 (120848) | 120848..121361 | - | 514 | Protein_149 | DUF4113 domain-containing protein | - |
| QET42_RS24045 (121422) | 121422..121526 | - | 105 | Protein_150 | AAA family ATPase | - |
| QET42_RS24050 (121528) | 121528..121851 | - | 324 | Protein_151 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|