MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 136334 bp
Accession: NZ_CP118399 Location: 1..136334 Organism: Klebsiella pneumoniae strain 2020CK-00223 Replicon: plasmid unnamed1
Accession: NZ_CP118399 Location: 1..136334 Organism: Klebsiella pneumoniae strain 2020CK-00223 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PWK27_RS26285 (PWK27_26285) | 1..1011 | + | 1011 | WP_000200070.1 | RepB family plasmid replication initiator protein | - |
| PWK27_RS26290 (PWK27_26290) | 1822..2802 | - | 981 | WP_014386491.1 | IS5 family transposase ISKpn26 | Transposase |
| PWK27_RS26295 (PWK27_26295) | 2929..3186 | + | 258 | WP_009310077.1 | hypothetical protein | - |
| PWK27_RS26300 (PWK27_26300) | 3244..4023 | - | 780 | WP_023287113.1 | site-specific integrase | - |
| PWK27_RS26305 (PWK27_26305) | 4221..5237 | - | 1017 | WP_009309921.1 | hypothetical protein | - |
| PWK27_RS26310 (PWK27_26310) | 5271..5606 | - | 336 | WP_009309920.1 | hypothetical protein | - |
| PWK27_RS26315 (PWK27_26315) | 5656..5796 | - | 141 | WP_162898808.1 | hypothetical protein | - |
| PWK27_RS26320 (PWK27_26320) | 6025..6330 | - | 306 | WP_009309918.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| PWK27_RS26325 (PWK27_26325) | 6332..6550 | - | 219 | WP_006788213.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| PWK27_RS26330 (PWK27_26330) | 7147..7377 | + | 231 | WP_001261276.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PWK27_RS26335 (PWK27_26335) | 7374..7790 | + | 417 | WP_009309917.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PWK27_RS26340 (PWK27_26340) | 7831..8709 | - | 879 | WP_009309916.1 | restriction endonuclease | - |
| PWK27_RS26345 (PWK27_26345) | 9371..10648 | + | 1278 | WP_009309915.1 | HlyD family secretion protein | - |
| PWK27_RS26350 (PWK27_26350) | 10638..12746 | + | 2109 | WP_032427226.1 | peptidase domain-containing ABC transporter | - |
| PWK27_RS26355 (PWK27_26355) | 12746..13381 | + | 636 | WP_009309912.1 | type II CAAX endopeptidase family protein | - |
| PWK27_RS26360 (PWK27_26360) | 13489..13830 | - | 342 | WP_071844672.1 | hypothetical protein | - |
| PWK27_RS26365 (PWK27_26365) | 14153..14683 | + | 531 | WP_223174905.1 | hypothetical protein | - |
| PWK27_RS26370 (PWK27_26370) | 14652..15089 | + | 438 | WP_009309910.1 | hypothetical protein | - |
| PWK27_RS26375 (PWK27_26375) | 15280..15720 | - | 441 | WP_047057603.1 | hypothetical protein | - |
| PWK27_RS26380 (PWK27_26380) | 15739..16362 | - | 624 | WP_223345396.1 | hypothetical protein | - |
| PWK27_RS26385 (PWK27_26385) | 16431..16667 | - | 237 | Protein_20 | hypothetical protein | - |
| PWK27_RS26390 (PWK27_26390) | 16624..16854 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PWK27_RS26395 (PWK27_26395) | 16851..17267 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PWK27_RS26400 (PWK27_26400) | 17341..18903 | + | 1563 | WP_009309907.1 | AAA family ATPase | - |
| PWK27_RS26405 (PWK27_26405) | 18888..19910 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| PWK27_RS26410 (PWK27_26410) | 20455..21363 | + | 909 | WP_032451458.1 | HNH endonuclease | - |
| PWK27_RS26415 (PWK27_26415) | 21549..21899 | - | 351 | WP_004187110.1 | DUF305 domain-containing protein | - |
| PWK27_RS26420 (PWK27_26420) | 21980..22948 | + | 969 | WP_077259451.1 | IS5 family transposase IS903 | Transposase |
| PWK27_RS26425 (PWK27_26425) | 23113..23544 | - | 432 | WP_009309902.1 | silver-binding protein SilE | - |
| PWK27_RS26430 (PWK27_26430) | 23790..25265 | - | 1476 | WP_009309901.1 | copper/silver sensor histidine kinase SilS | - |
| PWK27_RS26435 (PWK27_26435) | 25258..25938 | - | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| PWK27_RS26440 (PWK27_26440) | 26128..27513 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| PWK27_RS26445 (PWK27_26445) | 27542..27904 | + | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| PWK27_RS26450 (PWK27_26450) | 28018..29310 | + | 1293 | WP_009309900.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| PWK27_RS26455 (PWK27_26455) | 29321..32467 | + | 3147 | WP_009309899.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| PWK27_RS26460 (PWK27_26460) | 32554..32994 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| PWK27_RS26465 (PWK27_26465) | 33121..35568 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| PWK27_RS26470 (PWK27_26470) | 35609..35806 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| PWK27_RS26475 (PWK27_26475) | 35840..36577 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| PWK27_RS26480 (PWK27_26480) | 36866..37315 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| PWK27_RS26485 (PWK27_26485) | 37549..39366 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| PWK27_RS26490 (PWK27_26490) | 39372..40262 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| PWK27_RS26495 (PWK27_26495) | 40302..40682 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| PWK27_RS26500 (PWK27_26500) | 40738..41616 | + | 879 | WP_080821469.1 | copper resistance inner membrane protein PcoD | - |
| PWK27_RS26505 (PWK27_26505) | 41671..42351 | + | 681 | WP_009309896.1 | Transcriptional activator protein CopR | VF |
| PWK27_RS26510 (PWK27_26510) | 42348..43748 | + | 1401 | WP_009309895.1 | copper resistance membrane spanning protein PcoS | - |
| PWK27_RS26515 (PWK27_26515) | 43964..44398 | + | 435 | WP_009309894.1 | hypothetical protein | - |
| PWK27_RS26520 (PWK27_26520) | 44578..44740 | - | 163 | Protein_47 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PWK27_RS26525 (PWK27_26525) | 44777..44875 | - | 99 | WP_004118688.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PWK27_RS26530 (PWK27_26530) | 44980..45384 | + | 405 | WP_004196883.1 | IS66 family transposase ISEc22 | Transposase |
| PWK27_RS26535 (PWK27_26535) | 45381..45728 | + | 348 | WP_004196919.1 | IS66 family transposase ISKpn24 | Transposase |
| PWK27_RS26540 (PWK27_26540) | 45777..47315 | + | 1539 | WP_004196907.1 | IS66 family transposase ISEc22 | Transposase |
| PWK27_RS26545 (PWK27_26545) | 47605..47868 | + | 264 | WP_009310051.1 | hypothetical protein | - |
| PWK27_RS26550 (PWK27_26550) | 47865..48431 | + | 567 | WP_009310052.1 | hypothetical protein | - |
| PWK27_RS26555 (PWK27_26555) | 48462..48956 | + | 495 | WP_009310053.1 | hypothetical protein | - |
| PWK27_RS26560 (PWK27_26560) | 49000..49368 | + | 369 | WP_009310054.1 | hypothetical protein | - |
| PWK27_RS26565 (PWK27_26565) | 49399..49602 | + | 204 | WP_004098931.1 | HHA domain-containing protein | - |
| PWK27_RS26570 (PWK27_26570) | 49651..49908 | + | 258 | WP_004098928.1 | hypothetical protein | - |
| PWK27_RS26575 (PWK27_26575) | 49984..50238 | + | 255 | WP_004118702.1 | hypothetical protein | - |
| PWK27_RS26580 (PWK27_26580) | 50414..50680 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| PWK27_RS26585 (PWK27_26585) | 50668..51150 | + | 483 | WP_064179701.1 | GNAT family N-acetyltransferase | Toxin Detail |
| PWK27_RS26590 (PWK27_26590) | 51309..52841 | - | 1533 | WP_009310015.1 | IS3 family transposase ISKpn38 | Transposase |
| PWK27_RS26595 (PWK27_26595) | 52876..53454 | - | 579 | Protein_62 | urea ABC transporter permease subunit UrtB | - |
| PWK27_RS26600 (PWK27_26600) | 53511..54596 | - | 1086 | Protein_63 | urea ABC transporter substrate-binding protein | - |
| PWK27_RS26605 (PWK27_26605) | 54684..55710 | + | 1027 | Protein_64 | IS110 family transposase ISBcen3 | Transposase |
| PWK27_RS26610 (PWK27_26610) | 56005..56973 | + | 969 | WP_162492046.1 | IS5 family transposase IS903B | Transposase |
| PWK27_RS26615 (PWK27_26615) | 57291..58315 | - | 1025 | Protein_66 | IS110 family transposase ISAs16 | Transposase |
| PWK27_RS26620 (PWK27_26620) | 58490..59470 | + | 981 | WP_009310076.1 | IS5 family transposase ISKpn26 | Transposase |
| PWK27_RS26625 (PWK27_26625) | 59571..59756 | - | 186 | WP_274759737.1 | hypothetical protein | - |
| PWK27_RS26630 (PWK27_26630) | 60099..61103 | - | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| PWK27_RS26635 (PWK27_26635) | 61182..61739 | - | 558 | WP_017901435.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| PWK27_RS26640 (PWK27_26640) | 61762..62121 | - | 360 | WP_017901436.1 | cupin domain-containing protein | - |
| PWK27_RS26645 (PWK27_26645) | 62272..62661 | - | 390 | WP_017901438.1 | DUF86 domain-containing protein | - |
| PWK27_RS26650 (PWK27_26650) | 62658..62948 | - | 291 | WP_025999361.1 | nucleotidyltransferase family protein | - |
| PWK27_RS26655 (PWK27_26655) | 63105..66071 | + | 2967 | WP_032673378.1 | Tn3 family transposase TnpA_TnShfr1 | Transposase |
| PWK27_RS26660 (PWK27_26660) | 66150..67154 | + | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| PWK27_RS26665 (PWK27_26665) | 67416..67664 | - | 249 | Protein_76 | replication initiation protein | - |
| PWK27_RS26670 (PWK27_26670) | 67657..68208 | - | 552 | WP_022631532.1 | plasmid replication initiator RepA | - |
| PWK27_RS26675 (PWK27_26675) | 68490..68759 | - | 270 | WP_022631531.1 | replication regulatory protein RepA | - |
| PWK27_RS26680 (PWK27_26680) | 68895..69446 | - | 552 | WP_015065550.1 | Cardiolipin synthase A | VF |
| PWK27_RS26685 (PWK27_26685) | 69551..69859 | - | 309 | WP_032427369.1 | hypothetical protein | - |
| PWK27_RS26690 (PWK27_26690) | 69856..70506 | - | 651 | WP_014343480.1 | DUF2726 domain-containing protein | - |
| PWK27_RS26695 (PWK27_26695) | 70562..71206 | - | 645 | WP_004153014.1 | hypothetical protein | - |
| PWK27_RS26700 (PWK27_26700) | 71256..71858 | - | 603 | WP_015065545.1 | PIN domain-containing protein | - |
| PWK27_RS26705 (PWK27_26705) | 72019..72612 | - | 594 | WP_015065544.1 | fertility inhibition protein FinO | - |
| PWK27_RS26710 (PWK27_26710) | 72768..73493 | - | 726 | WP_015065543.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| PWK27_RS26715 (PWK27_26715) | 73573..78831 | - | 5259 | WP_135735356.1 | Multifunctional conjugation protein TraI | Relaxase |
| PWK27_RS26720 (PWK27_26720) | 78831..81143 | - | 2313 | WP_048292288.1 | type IV conjugative transfer system coupling protein TraD | - |
| PWK27_RS26725 (PWK27_26725) | 81270..81959 | - | 690 | WP_013023831.1 | hypothetical protein | - |
| PWK27_RS26730 (PWK27_26730) | 82152..82881 | - | 730 | Protein_89 | conjugal transfer complement resistance protein TraT | - |
| PWK27_RS26735 (PWK27_26735) | 83070..83261 | - | 192 | Protein_90 | conjugal transfer protein TraS | - |
| PWK27_RS26740 (PWK27_26740) | 83295..84263 | + | 969 | WP_274759733.1 | IS5 family transposase IS903B | Transposase |
| PWK27_RS26745 (PWK27_26745) | 84318..84605 | - | 288 | Protein_92 | transcriptional regulator | - |
| PWK27_RS26750 (PWK27_26750) | 84606..84884 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| PWK27_RS26755 (PWK27_26755) | 84874..85194 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PWK27_RS26760 (PWK27_26760) | 85275..85499 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| PWK27_RS26765 (PWK27_26765) | 85510..85722 | - | 213 | WP_019706020.1 | hypothetical protein | - |
| PWK27_RS26770 (PWK27_26770) | 85783..86139 | - | 357 | WP_019706019.1 | hypothetical protein | - |
| PWK27_RS26775 (PWK27_26775) | 86980..87297 | - | 318 | WP_015065519.1 | hypothetical protein | - |
| PWK27_RS26780 (PWK27_26780) | 87312..87662 | - | 351 | WP_032425551.1 | hypothetical protein | - |
| PWK27_RS26785 (PWK27_26785) | 87659..87931 | - | 273 | WP_032425552.1 | hypothetical protein | - |
| PWK27_RS26790 (PWK27_26790) | 88588..89556 | - | 969 | WP_072198477.1 | IS5 family transposase IS903B | Transposase |
| PWK27_RS26795 (PWK27_26795) | 89851..90957 | - | 1107 | Protein_102 | IS4 family transposase IS421 | Transposase |
| PWK27_RS26800 (PWK27_26800) | 91034..91152 | - | 119 | Protein_103 | type I toxin-antitoxin system Hok family toxin | - |
| PWK27_RS26805 (PWK27_26805) | 91263..92295 | + | 1033 | Protein_104 | IS481 family transposase ISKpn28 | Transposase |
| PWK27_RS26810 (PWK27_26810) | 92346..92633 | - | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin Detail |
| PWK27_RS26815 (PWK27_26815) | 92633..92872 | - | 240 | WP_004196370.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin Detail |
| PWK27_RS26820 (PWK27_26820) | 92897..92995 | + | 99 | Protein_107 | protein YdfV | - |
| PWK27_RS26825 (PWK27_26825) | 93123..93488 | + | 366 | WP_009651956.1 | hypothetical protein | - |
| PWK27_RS26830 (PWK27_26830) | 93532..94269 | + | 738 | WP_008460272.1 | HupE/UreJ family protein | - |
| PWK27_RS26835 (PWK27_26835) | 94283..94972 | + | 690 | WP_004196322.1 | hypothetical protein | - |
| PWK27_RS26840 (PWK27_26840) | 95003..96379 | - | 1377 | Protein_111 | chromate efflux transporter | - |
| PWK27_RS26845 (PWK27_26845) | 96336..97313 | - | 978 | WP_004196334.1 | chromate resistance protein | - |
| PWK27_RS26850 (PWK27_26850) | 97343..97535 | + | 193 | Protein_113 | MFS transporter | - |
| PWK27_RS26855 (PWK27_26855) | 97660..98031 | + | 372 | WP_004196359.1 | hypothetical protein | - |
| PWK27_RS26860 (PWK27_26860) | 98094..99014 | + | 921 | WP_004196315.1 | hypothetical protein | - |
| PWK27_RS26865 (PWK27_26865) | 99068..99826 | + | 759 | WP_004196325.1 | hypothetical protein | - |
| PWK27_RS26870 (PWK27_26870) | 100060..101358 | + | 1299 | WP_004196314.1 | MFS transporter | - |
| PWK27_RS26875 (PWK27_26875) | 101464..101733 | + | 270 | WP_004196355.1 | nickel-sensing transcriptional repressor NcrB | - |
| PWK27_RS26880 (PWK27_26880) | 101746..102876 | + | 1131 | WP_004196366.1 | Ni(II)/Co(II) efflux transporter permease subunit NcrC | - |
| PWK27_RS26885 (PWK27_26885) | 103038..103460 | + | 423 | WP_032072095.1 | nickel resistance OB fold protein NcrY | - |
| PWK27_RS26890 (PWK27_26890) | 103716..105056 | - | 1341 | WP_004196353.1 | ISNCY family transposase ISCARN112 | Transposase |
| PWK27_RS26895 (PWK27_26895) | 105145..106677 | + | 1533 | WP_009310015.1 | IS3 family transposase ISKpn38 | Transposase |
| PWK27_RS26900 (PWK27_26900) | 106807..107862 | + | 1056 | WP_274759734.1 | IS481 family transposase ISKpn28 | Transposase |
| PWK27_RS26905 (PWK27_26905) | 108795..109835 | - | 1041 | WP_009310020.1 | ATP-binding protein | - |
| PWK27_RS26915 (PWK27_26915) | 111581..111955 | - | 375 | WP_023280872.1 | hypothetical protein | - |
| PWK27_RS26920 (PWK27_26920) | 112011..112337 | - | 327 | WP_001568059.1 | hypothetical protein | - |
| PWK27_RS26925 (PWK27_26925) | 112334..113062 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| PWK27_RS26930 (PWK27_26930) | 113059..113490 | - | 432 | WP_020804497.1 | conjugation system SOS inhibitor PsiB | - |
| PWK27_RS26935 (PWK27_26935) | 113535..115592 | - | 2058 | WP_009310025.1 | ParB/RepB/Spo0J family partition protein | - |
| PWK27_RS26940 (PWK27_26940) | 115662..115910 | - | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| PWK27_RS26945 (PWK27_26945) | 115959..116501 | - | 543 | WP_021314431.1 | single-stranded DNA-binding protein | - |
| PWK27_RS26950 (PWK27_26950) | 117331..117894 | - | 564 | WP_025861951.1 | methyltransferase | - |
| PWK27_RS26955 (PWK27_26955) | 117942..119297 | - | 1356 | WP_032425555.1 | DUF3560 domain-containing protein | - |
| PWK27_RS26960 (PWK27_26960) | 119349..119579 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| PWK27_RS26965 (PWK27_26965) | 119671..119898 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| PWK27_RS26970 (PWK27_26970) | 120576..120896 | - | 321 | WP_031280552.1 | hypothetical protein | - |
| PWK27_RS26975 (PWK27_26975) | 120931..121185 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| PWK27_RS26980 (PWK27_26980) | 121373..121564 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| PWK27_RS26985 (PWK27_26985) | 121607..122113 | - | 507 | WP_042015157.1 | antirestriction protein ArdA | - |
| PWK27_RS26990 (PWK27_26990) | 122156..122584 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| PWK27_RS26995 (PWK27_26995) | 123265..124032 | - | 768 | WP_022631157.1 | hypothetical protein | - |
| PWK27_RS27000 (PWK27_27000) | 124086..124505 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| PWK27_RS27005 (PWK27_27005) | 124515..124736 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| PWK27_RS27010 (PWK27_27010) | 124736..125437 | - | 702 | WP_001568041.1 | DNA methylase | - |
| PWK27_RS27015 (PWK27_27015) | 125874..126104 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| PWK27_RS27020 (PWK27_27020) | 126167..126838 | - | 672 | WP_042015161.1 | plasmid partitioning/stability family protein | - |
| PWK27_RS27025 (PWK27_27025) | 126841..127812 | - | 972 | WP_032425559.1 | plasmid segregation protein ParM | - |
| PWK27_RS27030 (PWK27_27030) | 128061..129548 | - | 1488 | WP_162898809.1 | group II intron reverse transcriptase/maturase | - |
| PWK27_RS27035 (PWK27_27035) | 129951..130376 | + | 426 | WP_009309980.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| PWK27_RS27040 (PWK27_27040) | 130376..131647 | + | 1272 | WP_004206782.1 | Y-family DNA polymerase | - |
| PWK27_RS27045 (PWK27_27045) | 131726..131977 | + | 252 | WP_004206783.1 | plasmid stabilization protein | - |
| PWK27_RS27050 (PWK27_27050) | 132031..132336 | + | 306 | WP_009309981.1 | hypothetical protein | - |
| PWK27_RS27055 (PWK27_27055) | 133447..134418 | - | 972 | WP_009309982.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PWK27_RS27060 (PWK27_27060) | 134418..135584 | - | 1167 | WP_000523812.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|