MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 113066 bp
Accession: NZ_CP116168 Location: 1..113066 Organism: Escherichia coli strain DETEC-P169 Replicon: plasmid pDETEC2
Accession: NZ_CP116168 Location: 1..113066 Organism: Escherichia coli strain DETEC-P169 Replicon: plasmid pDETEC2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PID12_RS23825 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| PID12_RS23830 (1263) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| PID12_RS23835 (2124) | 2124..2312 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| PID12_RS23840 (2679) | 2679..3848 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| PID12_RS23845 (4074) | 4074..4249 | - | 176 | Protein_4 | IS3 family transposase | - |
| PID12_RS23850 (4695) | 4695..4967 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| PID12_RS23855 (5504) | 5504..5928 | - | 425 | Protein_6 | IS3 family transposase IS2 | Transposase |
| PID12_RS23860 (6210) | 6210..8180 | + | 1971 | WP_001496335.1 | Hemin receptor | VF |
| PID12_RS23865 (8187) | 8187..8978 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| PID12_RS23870 (9041) | 9041..9649 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| PID12_RS23875 (9717) | 9717..10499 | - | 783 | WP_001317493.1 | IS21 family transposase IS100kyp | Transposase |
| PID12_RS23880 (10496) | 10496..11518 | - | 1023 | WP_000255956.1 | IS21 family transposase IS100kyp | Transposase |
| PID12_RS23885 (11604) | 11604..12549 | - | 946 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| PID12_RS23890 (12598) | 12598..12972 | - | 375 | WP_024193849.1 | IS66 family transposase ISKpn24 | Transposase |
| PID12_RS23895 (12997) | 12997..13701 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PID12_RS23900 (13823) | 13823..14728 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| PID12_RS23905 (14725) | 14725..15963 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| PID12_RS23910 (15963) | 15963..16547 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| PID12_RS23915 (17040) | 17040..17804 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| PID12_RS23920 (17974) | 17974..18678 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PID12_RS23925 (18785) | 18785..19645 | + | 861 | WP_000557452.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| PID12_RS23930 (19658) | 19658..20200 | + | 543 | WP_002063889.1 | AAA family ATPase | - |
| PID12_RS23935 (20292) | 20292..21340 | + | 1049 | Protein_22 | IS3 family transposase ISKpn11 | Transposase |
| PID12_RS23940 (21394) | 21394..22098 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PID12_RS23945 (22175) | 22175..24394 | - | 2220 | Protein_24 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PID12_RS23950 (24459) | 24459..24752 | + | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| PID12_RS23955 (24799) | 24799..25674 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| PID12_RS23960 (25930) | 25930..26217 | - | 288 | Protein_27 | IS1380 family transposase ISEcp1 | Transposase |
| PID12_RS23965 (26283) | 26283..26987 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PID12_RS23970 (27041) | 27041..27481 | - | 441 | Protein_29 | CatB-related O-acetyltransferase | - |
| PID12_RS23975 (27619) | 27619..28449 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| PID12_RS23980 (28580) | 28580..29134 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| PID12_RS23985 (29278) | 29278..29982 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PID12_RS23990 (30048) | 30048..31562 | + | 1515 | Protein_33 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PID12_RS23995 (31604) | 31604..31846 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| PID12_RS24000 (31878) | 31878..32528 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| PID12_RS24005 (32634) | 32634..33833 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| PID12_RS24010 (33865) | 33865..34749 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| PID12_RS24015 (34887) | 34887..35279 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| PID12_RS24020 (35283) | 35283..36032 | + | 750 | Protein_39 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PID12_RS24025 (36056) | 36056..36661 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| PID12_RS24030 (36756) | 36756..39653 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| PID12_RS24035 (39790) | 39790..40191 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PID12_RS24040 (40124) | 40124..40381 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PID12_RS24045 (40474) | 40474..41127 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| PID12_RS24050 (42066) | 42066..42923 | - | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| PID12_RS24055 (42916) | 42916..42990 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| PID12_RS24060 (43225) | 43225..43482 | - | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| PID12_RS24065 (43887) | 43887..44909 | + | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| PID12_RS24070 (45381) | 45381..45734 | + | 354 | WP_000005489.1 | hypothetical protein | - |
| PID12_RS24075 (46147) | 46147..46725 | - | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| PID12_RS24080 (46758) | 46758..47455 | + | 698 | WP_223230354.1 | IS1 family transposase IS1S | Transposase |
| PID12_RS24085 (47570) | 47570..47926 | + | 357 | WP_000229735.1 | transposase | - |
| PID12_RS24090 (47923) | 47923..48273 | + | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| PID12_RS24095 (48304) | 48304..48525 | + | 222 | WP_000080227.1 | IS66 family transposase ISEc43 | Transposase |
| PID12_RS24100 (48477) | 48477..48818 | + | 342 | Protein_55 | transposase | - |
| PID12_RS24105 (48882) | 48882..49361 | - | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| PID12_RS24110 (49442) | 49442..50845 | - | 1404 | WP_000514417.1 | YfcC family protein | - |
| PID12_RS24115 (50893) | 50893..51897 | - | 1005 | WP_000154545.1 | Ornithine carbamoyltransferase | VF |
| PID12_RS24120 (51982) | 51982..52893 | - | 912 | WP_000440183.1 | carbamate kinase | - |
| PID12_RS24125 (52904) | 52904..54124 | - | 1221 | WP_000410951.1 | arginine deiminase | - |
| PID12_RS24130 (54831) | 54831..55445 | + | 615 | Protein_61 | VENN motif pre-toxin domain-containing protein | - |
| PID12_RS24135 (55445) | 55445..55891 | - | 447 | Protein_62 | plasmid replication initiator RepA | - |
| PID12_RS24140 (55884) | 55884..55958 | - | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| PID12_RS24145 (56194) | 56194..56451 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| PID12_RS24150 (56735) | 56735..56884 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56928) | 56928..56989 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (56928) | 56928..56989 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (56928) | 56928..56989 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (56928) | 56928..56989 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| PID12_RS24155 (57128) | 57128..57310 | - | 183 | WP_000968309.1 | hypothetical protein | - |
| PID12_RS24160 (57411) | 57411..58027 | + | 617 | Protein_67 | IS1 family transposase IS1G | Transposase |
| PID12_RS24165 (58107) | 58107..60128 | - | 2022 | Protein_68 | Multifunctional conjugation protein TraI | Relaxase |
| PID12_RS24170 (60128) | 60128..62326 | - | 2199 | WP_046464200.1 | type IV conjugative transfer system coupling protein TraD | - |
| PID12_RS24175 (62578) | 62578..63309 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| PID12_RS24180 (63323) | 63323..63832 | - | 510 | WP_000628100.1 | conjugal transfer entry exclusion protein TraS | - |
| PID12_RS24185 (63829) | 63829..65418 | - | 1590 | Protein_72 | conjugal transfer protein TraG | - |
| PID12_RS24190 (65483) | 65483..66211 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| PID12_RS24195 (66198) | 66198..66764 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| PID12_RS24200 (66786) | 66786..67085 | - | 300 | WP_241220505.1 | type IV conjugative transfer system protein TraL | - |
| PID12_RS24205 (67127) | 67127..67824 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| PID12_RS24210 (67835) | 67835..67942 | - | 108 | WP_271292905.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PID12_RS24215 (67899) | 67899..68033 | - | 135 | Protein_78 | plasmid maintenance protein Mok | - |
| - (68019) | 68019..68050 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (68019) | 68019..68050 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (68019) | 68019..68050 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (68019) | 68019..68050 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (69492) | 69492..69689 | - | 198 | NuclAT_0 | - | - |
| - (69492) | 69492..69689 | - | 198 | NuclAT_0 | - | - |
| - (69492) | 69492..69689 | - | 198 | NuclAT_0 | - | - |
| - (69492) | 69492..69689 | - | 198 | NuclAT_0 | - | - |
| PID12_RS24225 (69501) | 69501..69689 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| PID12_RS24230 (69658) | 69658..70420 | - | 763 | Protein_81 | plasmid SOS inhibition protein A | - |
| PID12_RS24235 (70417) | 70417..70851 | - | 435 | WP_000845937.1 | conjugation system SOS inhibitor PsiB | - |
| PID12_RS24240 (70906) | 70906..71103 | - | 198 | Protein_83 | hypothetical protein | - |
| PID12_RS24245 (71131) | 71131..71364 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| PID12_RS24250 (71432) | 71432..71929 | - | 498 | WP_042039995.1 | single-stranded DNA-binding protein | - |
| PID12_RS24255 (72079) | 72079..73980 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| PID12_RS24260 (74658) | 74658..74864 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| PID12_RS24265 (75104) | 75104..75355 | - | 252 | WP_071579736.1 | hypothetical protein | - |
| PID12_RS24270 (75274) | 75274..75480 | - | 207 | WP_001774176.1 | hypothetical protein | - |
| PID12_RS24275 (75506) | 75506..76071 | - | 566 | Protein_90 | class I SAM-dependent methyltransferase | - |
| PID12_RS24280 (76119) | 76119..77480 | - | 1362 | WP_000199439.1 | DUF3560 domain-containing protein | - |
| PID12_RS24285 (77532) | 77532..77762 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| PID12_RS24290 (78274) | 78274..78522 | + | 249 | WP_071781657.1 | hypothetical protein | - |
| PID12_RS24295 (78794) | 78794..78985 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| PID12_RS24300 (78982) | 78982..79404 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| PID12_RS24305 (79451) | 79451..79876 | - | 426 | WP_001546490.1 | antirestriction protein | - |
| PID12_RS24310 (80290) | 80290..81060 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| PID12_RS24315 (81105) | 81105..81623 | - | 519 | WP_223349485.1 | DUF1380 family protein | - |
| PID12_RS24320 (81553) | 81553..81774 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| PID12_RS24325 (81775) | 81775..82458 | - | 684 | WP_032181561.1 | DNA methylase | - |
| PID12_RS24330 (82535) | 82535..82846 | - | 312 | WP_012615291.1 | hypothetical protein | - |
| PID12_RS24335 (82843) | 82843..83745 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| PID12_RS24340 (84483) | 84483..85454 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PID12_RS24345 (85454) | 85454..86620 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| PID12_RS24350 (87208) | 87208..87963 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| PID12_RS24355 (88685) | 88685..89491 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| PID12_RS24360 (89492) | 89492..89797 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| PID12_RS24365 (89799) | 89799..90017 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| PID12_RS24370 (90577) | 90577..90807 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PID12_RS24375 (90804) | 90804..91220 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PID12_RS24380 (91295) | 91295..92860 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| PID12_RS24385 (92845) | 92845..93867 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| PID12_RS24390 (94121) | 94121..94807 | - | 687 | Protein_113 | IS1 family transposase IS1S | Transposase |
| PID12_RS24395 (95333) | 95333..97534 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| PID12_RS24400 (97560) | 97560..98893 | - | 1334 | Protein_115 | L-lysine N6-monooxygenase | VF |
| PID12_RS24405 (98890) | 98890..100632 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| PID12_RS24410 (100632) | 100632..101579 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| PID12_RS24415 (101580) | 101580..103304 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| PID12_RS24420 (103440) | 103440..104633 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| PID12_RS24425 (105013) | 105013..105393 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| PID12_RS24430 (105734) | 105734..106147 | - | 414 | Protein_121 | phosphopyruvate hydratase | - |
| PID12_RS24435 (106145) | 106145..106402 | + | 258 | Protein_122 | Tn3 family transposase | - |
| PID12_RS24440 (106636) | 106636..107493 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| PID12_RS24445 (107490) | 107490..108347 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| PID12_RS24450 (108344) | 108344..109171 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| PID12_RS24455 (109171) | 109171..110085 | - | 915 | WP_000949005.1 | putative periplasmic iron-binding protein | VF |
| PID12_RS24460 (110441) | 110441..111138 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| PID12_RS24465 (111318) | 111318..111831 | - | 514 | Protein_128 | DUF4113 domain-containing protein | - |
| PID12_RS24470 (111892) | 111892..111996 | - | 105 | Protein_129 | AAA family ATPase | - |
| PID12_RS24475 (111998) | 111998..112321 | - | 324 | Protein_130 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|