MGE detailed information
MGE type: Conjugative plasmid MGE length: 116501 bp
Accession: NZ_CP116160 Location: 1..116501 Organism: Escherichia coli strain DETEC-P351 Replicon: plasmid pDETEC5
Accession: NZ_CP116160 Location: 1..116501 Organism: Escherichia coli strain DETEC-P351 Replicon: plasmid pDETEC5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC26_RS23185 (1) | 1..858 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| PIC26_RS23190 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| PIC26_RS23195 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PIC26_RS23200 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PIC26_RS23205 (3271) | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| PIC26_RS23210 (6263) | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| PIC26_RS23215 (6892) | 6892..7641 | - | 750 | Protein_6 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PIC26_RS23220 (7645) | 7645..8037 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| PIC26_RS23225 (8175) | 8175..9059 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| PIC26_RS23230 (9091) | 9091..10290 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| PIC26_RS23235 (10396) | 10396..11046 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| PIC26_RS23240 (11078) | 11078..11320 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| PIC26_RS23245 (11362) | 11362..12876 | - | 1515 | Protein_12 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PIC26_RS23250 (12942) | 12942..13646 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC26_RS23255 (13699) | 13699..13947 | - | 249 | Protein_14 | DUF3330 domain-containing protein | - |
| PIC26_RS23260 (14150) | 14150..15163 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| PIC26_RS23265 (15321) | 15321..15794 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| PIC26_RS23270 (15925) | 15925..16713 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| PIC26_RS23275 (16919) | 16919..17266 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| PIC26_RS23280 (17260) | 17260..18099 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| PIC26_RS23285 (18227) | 18227..18430 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| PIC26_RS23290 (18586) | 18586..19791 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| PIC26_RS23295 (19802) | 19802..20107 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| PIC26_RS23300 (20151) | 20151..20216 | + | 66 | Protein_23 | EAL domain-containing protein | - |
| PIC26_RS23305 (20334) | 20334..21098 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| PIC26_RS23310 (21591) | 21591..22175 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| PIC26_RS23315 (22175) | 22175..23413 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| PIC26_RS23320 (23410) | 23410..24315 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| PIC26_RS23325 (24437) | 24437..25141 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC26_RS23330 (25202) | 25202..27613 | + | 2412 | Protein_29 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| PIC26_RS23335 (27647) | 27647..27751 | + | 105 | Protein_30 | IS5/IS1182 family transposase | - |
| PIC26_RS23340 (27901) | 27901..28533 | - | 633 | Protein_31 | histidine-type phosphatase | - |
| PIC26_RS23345 (28655) | 28655..29140 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| PIC26_RS23350 (29165) | 29165..29650 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| PIC26_RS23355 (29637) | 29637..30332 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| PIC26_RS23360 (30337) | 30337..31467 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| PIC26_RS23365 (31457) | 31457..32740 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| PIC26_RS23370 (32743) | 32743..34122 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| PIC26_RS23375 (34226) | 34226..34753 | - | 528 | WP_000178050.1 | iron transporter | - |
| PIC26_RS23380 (34794) | 34794..36680 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| PIC26_RS23385 (37027) | 37027..37788 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| PIC26_RS23390 (38025) | 38025..38531 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| PIC26_RS23395 (38521) | 38521..38691 | - | 171 | Protein_42 | DsbA family protein | - |
| PIC26_RS23400 (38829) | 38829..38942 | - | 114 | Protein_43 | IS6 family transposase | - |
| PIC26_RS23405 (39142) | 39142..39839 | + | 698 | WP_223350503.1 | IS1 family transposase IS1X2 | Transposase |
| PIC26_RS23410 (39989) | 39989..40675 | + | 687 | Protein_45 | IS1 family transposase IS1S | Transposase |
| PIC26_RS23415 (40929) | 40929..41951 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| PIC26_RS23420 (41936) | 41936..43501 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| PIC26_RS23425 (43576) | 43576..43992 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PIC26_RS23430 (43989) | 43989..44219 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PIC26_RS23435 (44779) | 44779..44997 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| PIC26_RS23440 (44999) | 44999..45304 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| PIC26_RS23445 (45305) | 45305..46111 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| PIC26_RS23450 (46833) | 46833..47588 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| PIC26_RS23455 (48176) | 48176..49342 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| PIC26_RS23460 (49342) | 49342..50313 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PIC26_RS23465 (51051) | 51051..51953 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| PIC26_RS23470 (51950) | 51950..52261 | + | 312 | WP_012615291.1 | hypothetical protein | - |
| PIC26_RS23475 (52338) | 52338..53021 | + | 684 | WP_106493938.1 | DNA methylase | - |
| PIC26_RS23480 (53022) | 53022..53243 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| PIC26_RS23485 (53173) | 53173..53691 | + | 519 | WP_223349485.1 | DUF1380 family protein | - |
| PIC26_RS23490 (53736) | 53736..54506 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| PIC26_RS23495 (54920) | 54920..55345 | + | 426 | WP_001546490.1 | antirestriction protein | - |
| PIC26_RS23500 (55392) | 55392..55814 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| PIC26_RS23505 (55811) | 55811..56002 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| PIC26_RS23510 (56274) | 56274..56522 | - | 249 | WP_071781657.1 | hypothetical protein | - |
| PIC26_RS23515 (57039) | 57039..57269 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| PIC26_RS23520 (57321) | 57321..58682 | + | 1362 | WP_039023242.1 | DUF3560 domain-containing protein | - |
| PIC26_RS23525 (58730) | 58730..59293 | + | 564 | WP_029702196.1 | class I SAM-dependent methyltransferase | - |
| PIC26_RS23530 (59445) | 59445..59735 | + | 291 | WP_073972921.1 | hypothetical protein | - |
| PIC26_RS23535 (60666) | 60666..61235 | - | 570 | WP_089634947.1 | hypothetical protein | - |
| PIC26_RS23545 (62539) | 62539..63297 | + | 759 | Protein_72 | site-specific integrase | - |
| PIC26_RS23550 (63455) | 63455..64465 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| PIC26_RS23555 (64561) | 64561..66687 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| PIC26_RS23560 (66750) | 66750..68027 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| PIC26_RS23565 (68027) | 68027..69457 | + | 1431 | WP_000813680.1 | glycoside hydrolase family 32 protein | - |
| PIC26_RS23570 (69652) | 69652..71046 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| PIC26_RS23575 (71292) | 71292..71396 | - | 105 | Protein_78 | thiosulfate reductase cytochrome B subunit | - |
| PIC26_RS23580 (71453) | 71453..72146 | + | 694 | Protein_79 | IS1 family transposase IS1A | Transposase |
| PIC26_RS23585 (72273) | 72273..72785 | + | 513 | WP_223350513.1 | potassium channel family protein | - |
| PIC26_RS23590 (72870) | 72870..73121 | + | 252 | Protein_81 | iron-containing alcohol dehydrogenase | - |
| PIC26_RS23595 (73410) | 73410..73727 | - | 318 | Protein_82 | IS110 family transposase IS1618 | Transposase |
| PIC26_RS23600 (73882) | 73882..73987 | + | 106 | Protein_83 | plasmid SOS inhibition protein A | - |
| - (73956) | 73956..74154 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (73956) | 73956..74154 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (73956) | 73956..74154 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (73956) | 73956..74154 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| PIC26_RS23605 (74161) | 74161..74310 | + | 150 | Protein_84 | DUF5431 family protein | - |
| PIC26_RS23610 (74252) | 74252..74377 | + | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PIC26_RS23615 (74678) | 74678..74975 | - | 298 | Protein_86 | hypothetical protein | - |
| PIC26_RS23620 (75045) | 75045..75251 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| PIC26_RS23625 (75276) | 75276..75563 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| PIC26_RS23630 (75682) | 75682..76503 | + | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| PIC26_RS23635 (76799) | 76799..77371 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| PIC26_RS23640 (77741) | 77741..78124 | + | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PIC26_RS23645 (78315) | 78315..78962 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| PIC26_RS23650 (79098) | 79098..79313 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| PIC26_RS23655 (79356) | 79356..79721 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| PIC26_RS23660 (79736) | 79736..80047 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| PIC26_RS23665 (80069) | 80069..80635 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| PIC26_RS23670 (80622) | 80622..81350 | + | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| PIC26_RS23675 (81350) | 81350..82777 | + | 1428 | WP_001553836.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PIC26_RS23680 (82767) | 82767..83357 | + | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PIC26_RS23685 (83344) | 83344..83664 | + | 321 | Protein_100 | conjugal transfer protein TrbD | - |
| PIC26_RS23690 (83657) | 83657..83908 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| PIC26_RS23695 (83905) | 83905..84420 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PIC26_RS23700 (84555) | 84555..84776 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| PIC26_RS23705 (84936) | 84936..87563 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| PIC26_RS23710 (87560) | 87560..87946 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| PIC26_RS23715 (87943) | 87943..88575 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| PIC26_RS23720 (88572) | 88572..89564 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| PIC26_RS23725 (89573) | 89573..90211 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PIC26_RS23730 (90208) | 90208..92016 | + | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PIC26_RS23735 (92043) | 92043..92300 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| PIC26_RS23740 (92293) | 92293..93036 | + | 744 | WP_271286581.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PIC26_RS23745 (93052) | 93052..93399 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| PIC26_RS23750 (93518) | 93518..93802 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PIC26_RS23755 (93789) | 93789..94334 | + | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PIC26_RS23760 (94264) | 94264..94626 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| PIC26_RS23765 (94626) | 94626..95999 | + | 1374 | WP_039023150.1 | conjugal transfer pilus assembly protein TraH | - |
| PIC26_RS23770 (95996) | 95996..98815 | + | 2820 | WP_039023149.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PIC26_RS23775 (98834) | 98834..99331 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| PIC26_RS23780 (99363) | 99363..100094 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| PIC26_RS23785 (100347) | 100347..102572 | + | 2226 | WP_106493937.1 | type IV conjugative transfer system coupling protein TraD | - |
| PIC26_RS23790 (102581) | 102581..102979 | - | 399 | WP_039023147.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PIC26_RS23795 (102979) | 102979..103206 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| PIC26_RS23800 (103288) | 103288..108558 | + | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
| PIC26_RS23805 (108834) | 108834..110375 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| PIC26_RS23810 (110390) | 110390..111136 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| PIC26_RS23815 (111164) | 111164..111910 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| PIC26_RS23820 (111965) | 111965..112525 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| PIC26_RS23825 (112656) | 112656..112865 | + | 210 | WP_039023209.1 | hypothetical protein | - |
| PIC26_RS23830 (113277) | 113277..113903 | + | 627 | WP_029702149.1 | NYN domain-containing protein | - |
| PIC26_RS23835 (114055) | 114055..114624 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| PIC26_RS23840 (114837) | 114837..115265 | + | 429 | WP_029702151.1 | hypothetical protein | - |
| - (115404) | 115404..115465 | - | 62 | NuclAT_1 | - | - |
| - (115404) | 115404..115465 | - | 62 | NuclAT_1 | - | - |
| - (115404) | 115404..115465 | - | 62 | NuclAT_1 | - | - |
| - (115404) | 115404..115465 | - | 62 | NuclAT_1 | - | - |
| PIC26_RS23845 (115509) | 115509..115658 | + | 150 | WP_001367749.1 | Hok/Gef family protein | - |
| PIC26_RS23850 (115942) | 115942..116199 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| PIC26_RS23855 (116304) | 116304..116489 | + | 186 | WP_077818652.1 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|