MGE detailed information

MGE type: Conjugative plasmid        MGE length: 161920 bp
Accession: NZ_CP110817        Location: 1..161920         Organism: Escherichia coli strain THB42-F5       Replicon: plasmid pHB42-F5


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0566_RS22375 (109) 109..357 + 249 WP_000083837.1 replication regulatory protein RepA -
N0566_RS22380 (472) 472..650 + 179 Protein_1 protein CopA/IncA -
N0566_RS22385 (669) 669..1526 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
N0566_RS22390 (2440) 2440..2709 + 270 WP_089438644.1 type II toxin-antitoxin system antitoxin YacA -
N0566_RS22395 (2709) 2709..2987 + 279 Protein_4 type II toxin-antitoxin system toxin YacB -
N0566_RS22400 (3033) 3033..3713 + 681 WP_226156984.1 3'-5' exonuclease -
N0566_RS22405 (3759) 3759..4655 - 897 WP_226156987.1 hypothetical protein -
N0566_RS22410 (4797) 4797..5162 - 366 WP_226156990.1 hypothetical protein -
N0566_RS22415 (5477) 5477..6664 - 1188 WP_226156993.1 IS91 family transposase ISEc37 Transposase
N0566_RS22420 (6664) 6664..7029 - 366 WP_226156997.1 hypothetical protein -
N0566_RS22425 (7473) 7473..8701 + 1229 WP_162843061.1 IS3 family transposase IS2 Transposase
N0566_RS22430 (8861) 8861..13543 + 4683 WP_226156943.1 hypothetical protein VF
N0566_RS22435 (13956) 13956..14267 + 312 WP_259904982.1 hypothetical protein -
N0566_RS22440 (14795) 14795..18610 + 3816 WP_226156939.1 hypothetical protein -
N0566_RS22445 (18946) 18946..19694 + 749 Protein_14 ISKra4 family transposase ISEc51 Transposase
N0566_RS22450 (20055) 20055..20573 - 519 WP_259904984.1 DUF4238 domain-containing protein -
N0566_RS22455 (20880) 20880..21164 + 285 WP_075858633.1 ribbon-helix-helix protein, CopG family Antitoxin Detail
N0566_RS22460 (21164) 21164..21439 + 276 WP_226156935.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
N0566_RS22465 (21546) 21546..21749 + 204 Protein_18 hypothetical protein -
N0566_RS22470 (22046) 22046..22345 + 300 WP_226156930.1 hypothetical protein -
N0566_RS22480 (23174) 23174..24688 - 1515 Protein_21 Tn3 family transposase TnpA_TnAs1 Transposase
N0566_RS22485 (24754) 24754..25458 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22490 (25511) 25511..26266 + 756 Protein_23 IS110 family transposase IS5075 Transposase
N0566_RS22495 (26538) 26538..26624 - 87 Protein_24 Arm DNA-binding domain-containing protein -
N0566_RS22500 (26954) 26954..27769 + 816 WP_001043260.1 Dihydropteroate synthase ARG
N0566_RS22505 (27830) 27830..28633 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
N0566_RS22510 (28633) 28633..29469 + 837 WP_000480972.1 hypothetical protein ARG
N0566_RS22515 (29775) 29775..30017 + 243 WP_000844627.1 transposase -
N0566_RS22520 (30049) 30049..30699 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
N0566_RS22525 (30805) 30805..32004 + 1200 WP_032153701.1 Tetracycline resistance protein, class C ARG
N0566_RS22530 (31971) 31971..32159 - 189 Protein_31 IS91 family transposase -
N0566_RS22535 (32271) 32271..32576 - 306 WP_001255015.1 HTH-type transcriptional regulator HdfR VF
N0566_RS22540 (32604) 32604..33818 - 1215 WP_023300759.1 Bicyclomycin resistance protein ARG
N0566_RS22545 (34035) 34035..34919 - 885 WP_021598067.1 DUF3363 domain-containing protein -
N0566_RS22550 (34950) 34950..36443 - 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
N0566_RS22555 (36654) 36654..36878 - 225 WP_000743213.1 hypothetical protein -
N0566_RS22560 (36875) 36875..37612 - 738 WP_001366550.1 Tn3 family transposase TnpR_TnEc1 Transposase
N0566_RS22565 (38024) 38024..38728 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22570 (38793) 38793..39002 + 210 Protein_39 IS1 family transposase -
N0566_RS22575 (40300) 40300..40479 + 180 WP_000347021.1 hypothetical protein -
N0566_RS22580 (40595) 40595..41239 - 645 WP_000203199.1 Tn3 family transposase TnpR_TnEc1 Transposase
N0566_RS22585 (41534) 41534..42154 + 621 WP_000864788.1 ParA family protein -
N0566_RS22590 (42206) 42206..42436 + 231 WP_000051066.1 plasmid partition protein ParG -
N0566_RS22595 (42860) 42860..43924 + 1065 WP_012291478.1 ParA family protein -
N0566_RS22600 (44462) 44462..44815 - 354 WP_024129958.1 DNA distortion polypeptide 3 -
N0566_RS22605 (44952) 44952..45398 - 447 WP_001074384.1 hypothetical protein -
N0566_RS22610 (45402) 45402..46244 - 843 WP_000435064.1 replication initiation protein -
N0566_RS22615 (46265) 46265..47104 - 840 WP_024129959.1 replication initiation protein -
N0566_RS22620 (48339) 48339..48590 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin Detail
N0566_RS22625 (48580) 48580..48861 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
N0566_RS22630 (49100) 49100..49192 - 93 Protein_51 IS6 family transposase -
N0566_RS22635 (49358) 49358..50557 - 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
N0566_RS22640 (50567) 50567..50755 - 189 WP_000957857.1 hypothetical protein -
N0566_RS22645 (50875) 50875..52305 + 1431 Protein_54 IS4 family transposase IS50R Transposase
N0566_RS22650 (52334) 52334..53128 + 795 WP_000572405.1 Aminoglycoside 3'-phosphotransferase ARG
N0566_RS22655 (53149) 53149..53385 + 237 Protein_56 hypothetical protein -
N0566_RS22660 (53435) 53435..54139 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22665 (54085) 54085..54591 - 507 WP_250697724.1 replication initiation protein -
N0566_RS22670 (54597) 54597..55301 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22675 (55500) 55500..55823 - 324 WP_001175594.1 metalloregulator ArsR/SmtB family transcription factor -
N0566_RS22680 (55928) 55928..56965 + 1038 WP_044502555.1 permease -
N0566_RS22685 (57258) 57258..57875 - 618 WP_000521603.1 ProQ/FINO family protein -
N0566_RS22690 (58067) 58067..59623 - 1557 WP_000818556.1 AAA family ATPase -
N0566_RS22695 (59886) 59886..60476 - 591 WP_000194575.1 hypothetical protein -
N0566_RS22700 (60476) 60476..60733 - 258 WP_000343085.1 hypothetical protein -
N0566_RS22705 (61087) 61087..63225 + 2139 WP_000350638.1 AAA family ATPase -
N0566_RS22710 (63387) 63387..63803 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
N0566_RS22715 (63800) 63800..64030 - 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
N0566_RS22720 (64326) 64326..64616 + 291 WP_000111771.1 hypothetical protein -
N0566_RS22725 (64606) 64606..65505 + 900 WP_000963206.1 nucleotide-binding protein -
N0566_RS22730 (65555) 65555..67780 - 2226 WP_000698737.1 P-loop NTPase fold protein -
N0566_RS22735 (67782) 67782..68870 - 1089 WP_000952217.1 transcriptional repressor PifC -
N0566_RS22740 (69413) 69413..69763 + 351 WP_000493378.1 hypothetical protein -
N0566_RS22745 (69814) 69814..70557 + 744 WP_000129823.1 hypothetical protein -
N0566_RS22750 (70554) 70554..71330 + 777 WP_000015958.1 site-specific integrase -
N0566_RS22755 (71388) 71388..71645 - 258 WP_000764642.1 hypothetical protein -
N0566_RS22760 (71774) 71774..71878 - 105 WP_032409716.1 hypothetical protein -
N0566_RS22765 (72408) 72408..73274 + 867 WP_004118283.1 replication initiation protein -
N0566_RS22770 (73451) 73451..73720 - 270 WP_000339857.1 hypothetical protein -
N0566_RS22775 (74135) 74135..75340 + 1206 WP_000368714.1 AAA family ATPase -
N0566_RS22780 (75340) 75340..76314 + 975 WP_000064119.1 ParB family protein -
N0566_RS22785 (76396) 76396..77667 - 1272 WP_001754953.1 Y-family DNA polymerase -
N0566_RS22790 (77667) 77667..78098 - 432 WP_000776034.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
N0566_RS22795 (78504) 78504..79991 + 1488 Protein_84 group II intron reverse transcriptase/maturase -
N0566_RS22800 (80143) 80143..80840 + 698 WP_223229472.1 IS1 family transposase IS1X3 Transposase
N0566_RS22805 (80850) 80850..81158 + 309 Protein_86 replication initiation protein -
N0566_RS22810 (82550) 82550..83518 + 969 WP_030005799.1 IS5 family transposase IS903B Transposase
N0566_RS22815 (83658) 83658..84044 - 387 WP_001039464.1 plasmid stabilization protein StbA -
N0566_RS22820 (84626) 84626..84859 + 234 Protein_89 transposase -
N0566_RS22825 (84892) 84892..87858 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
N0566_RS22830 (87862) 87862..88422 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
N0566_RS22835 (88598) 88598..88948 - 351 WP_000454193.1 DUF3330 domain-containing protein -
N0566_RS22840 (89151) 89151..90164 - 1014 WP_104774822.1 IS91 family transposase ISAzo26 Transposase
N0566_RS22845 (90309) 90309..90806 + 498 WP_001083725.1 IS1595 family transposase ISSsu9 ARG
N0566_RS22850 (90918) 90918..91208 + 291 WP_001336345.1 DUF1010 domain-containing protein -
N0566_RS22855 (91214) 91214..92052 + 839 Protein_96 Streptomycin 3''-adenylyltransferase ARG
N0566_RS22860 (92169) 92169..92516 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
N0566_RS22865 (92510) 92510..92842 + 333 Protein_98 IS6 family transposase IS15 Transposase
N0566_RS22870 (92899) 92899..93603 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22875 (93732) 93732..94496 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
N0566_RS22880 (94989) 94989..95573 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
N0566_RS22885 (95573) 95573..96811 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
N0566_RS22890 (96808) 96808..97713 - 906 WP_000219391.1 hypothetical protein ARG
N0566_RS22895 (97835) 97835..98539 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22900 (98850) 98850..99407 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
N0566_RS22905 (99590) 99590..100450 + 861 WP_000027057.1 Beta-lactamase TEM ARG
N0566_RS22910 (100620) 100620..101375 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
N0566_RS22915 (101501) 101501..102205 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22920 (102255) 102255..102998 + 744 Protein_109 Beta-lactamase TEM ARG
N0566_RS22925 (103257) 103257..103733 + 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
N0566_RS22930 (103780) 103780..104655 - 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
N0566_RS22935 (105077) 105077..105781 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0566_RS22940 (107361) 107361..107595 + 235 Protein_113 type II toxin-antitoxin system RelE/ParE family toxin -
N0566_RS22945 (107723) 107723..107926 + 204 Protein_114 hypothetical protein -
N0566_RS22950 (108127) 108127..108477 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
N0566_RS22955 (108480) 108480..109442 - 963 WP_000959884.1 plasmid segregation protein ParM -
N0566_RS22960 (109589) 109589..109882 + 294 WP_032146011.1 hypothetical protein -
N0566_RS22965 (109959) 109959..110642 + 684 WP_000085883.1 DNA methylase -
N0566_RS22970 (110643) 110643..110864 + 222 WP_001104881.1 hypothetical protein -
N0566_RS22975 (110878) 110878..111312 + 435 WP_000274503.1 DUF1380 family protein -
N0566_RS22980 (111363) 111363..112139 + 777 WP_001383963.1 hypothetical protein -
N0566_RS22985 (112557) 112557..112982 + 426 WP_001198928.1 antirestriction protein -
N0566_RS22990 (113029) 113029..113451 + 423 WP_000271762.1 DUF1380 family protein -
N0566_RS22995 (113448) 113448..113639 + 192 WP_001027493.1 hypothetical protein -
N0566_RS23000 (114677) 114677..114907 + 231 WP_000218642.1 hypothetical protein -
N0566_RS23005 (114959) 114959..116320 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
N0566_RS23010 (116367) 116367..116930 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
N0566_RS23015 (117016) 117016..117477 - 462 Protein_128 hypothetical protein -
N0566_RS23020 (117779) 117779..118306 + 528 WP_000290834.1 single-stranded DNA-binding protein -
N0566_RS23025 (118364) 118364..118597 + 234 WP_000006003.1 DUF905 family protein -
N0566_RS23030 (118658) 118658..120626 + 1969 Protein_131 ParB/RepB/Spo0J family partition protein -
N0566_RS23035 (120695) 120695..121129 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
N0566_RS23040 (121126) 121126..121888 + 763 Protein_133 plasmid SOS inhibition protein A -
- (121857) 121857..122081 + 225 NuclAT_0 - -
- (121857) 121857..122081 + 225 NuclAT_0 - -
- (121857) 121857..122081 + 225 NuclAT_0 - -
- (121857) 121857..122081 + 225 NuclAT_0 - -
N0566_RS23045 (122067) 122067..122216 + 150 Protein_134 plasmid maintenance protein Mok -
N0566_RS23050 (122158) 122158..122283 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
N0566_RS23055 (122602) 122602..122898 - 297 Protein_136 hypothetical protein -
N0566_RS23060 (123198) 123198..123494 + 297 WP_001272251.1 hypothetical protein -
N0566_RS23065 (123605) 123605..124426 + 822 WP_001234445.1 DUF932 domain-containing protein -
N0566_RS23070 (124723) 124723..125370 - 648 WP_015059008.1 hypothetical protein VF
N0566_RS23075 (125647) 125647..126030 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
N0566_RS23080 (126221) 126221..126907 + 687 WP_015059009.1 PAS domain-containing protein -
N0566_RS23085 (127001) 127001..127228 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
N0566_RS23090 (127262) 127262..127627 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
N0566_RS23095 (127642) 127642..127953 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
N0566_RS23100 (127975) 127975..128541 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
N0566_RS23105 (128528) 128528..129256 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
N0566_RS23110 (129256) 129256..130683 + 1428 WP_032297072.1 F-type conjugal transfer pilus assembly protein TraB -
N0566_RS23115 (130673) 130673..131263 + 591 WP_000002778.1 conjugal transfer pilus-stabilizing protein TraP -
N0566_RS23120 (131250) 131250..131447 + 198 WP_001324648.1 conjugal transfer protein TrbD -
N0566_RS23125 (131459) 131459..131710 + 252 WP_001038341.1 conjugal transfer protein TrbG -
N0566_RS23130 (131707) 131707..132222 + 516 WP_000809902.1 type IV conjugative transfer system lipoprotein TraV -
N0566_RS23135 (132357) 132357..132578 + 222 WP_001278692.1 conjugal transfer protein TraR -
N0566_RS23140 (132738) 132738..135365 + 2628 WP_015059012.1 type IV secretion system protein TraC -
N0566_RS23145 (135362) 135362..135748 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
N0566_RS23150 (135745) 135745..136377 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
N0566_RS23155 (136374) 136374..137366 + 993 WP_259904979.1 conjugal transfer pilus assembly protein TraU -
N0566_RS23160 (137393) 137393..137701 + 309 WP_000412447.1 hypothetical protein -
N0566_RS23165 (137764) 137764..138285 + 522 WP_015059014.1 hypothetical protein -
N0566_RS23170 (138312) 138312..138950 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
N0566_RS23175 (138947) 138947..139318 + 372 WP_000056336.1 hypothetical protein -
N0566_RS23180 (139344) 139344..139766 + 423 WP_001229309.1 HNH endonuclease signature motif containing protein -
N0566_RS23185 (139763) 139763..141613 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
N0566_RS23190 (141640) 141640..141897 + 258 WP_000864321.1 conjugal transfer protein TrbE -
N0566_RS23195 (141890) 141890..142633 + 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
N0566_RS23200 (142794) 142794..143030 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
N0566_RS23205 (143017) 143017..143562 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
N0566_RS23210 (143552) 143552..143866 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
N0566_RS23215 (143820) 143820..144212 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
N0566_RS23220 (144199) 144199..145572 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
N0566_RS23225 (145569) 145569..148385 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
N0566_RS23230 (148418) 148418..148939 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
N0566_RS23235 (148964) 148964..149695 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
N0566_RS23240 (149898) 149898..150635 + 738 WP_015059020.1 hypothetical protein -
N0566_RS23245 (150686) 150686..152929 + 2244 WP_072646483.1 type IV conjugative transfer system coupling protein TraD -
N0566_RS23250 (152929) 152929..158199 + 5271 WP_061093447.1 Multifunctional conjugation protein TraI Relaxase
N0566_RS23255 (158219) 158219..158965 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
N0566_RS23260 (159020) 159020..159580 + 561 WP_000139328.1 fertility inhibition protein FinO -
N0566_RS23265 (159712) 159712..159912 + 201 WP_015059022.1 hypothetical protein -
N0566_RS23270 (160298) 160298..160897 + 600 WP_032083981.1 PIN domain-containing protein -
- (161492) 161492..161551 - 60 NuclAT_1 - -
- (161492) 161492..161551 - 60 NuclAT_1 - -
- (161492) 161492..161551 - 60 NuclAT_1 - -
- (161492) 161492..161551 - 60 NuclAT_1 - -
N0566_RS23275 (161596) 161596..161745 + 150 WP_001312851.1 Hok/Gef family protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance