MGE detailed information
MGE type: Conjugative plasmid MGE length: 133669 bp
Accession: NZ_CP104534 Location: 1..133669 Organism: Escherichia coli strain E10 Replicon: plasmid p1
Accession: NZ_CP104534 Location: 1..133669 Organism: Escherichia coli strain E10 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N5O77_RS25125 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| N5O77_RS25130 (1263) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| N5O77_RS25135 (2124) | 2124..2312 | - | 189 | WP_001332052.1 | hypothetical protein | - |
| N5O77_RS25140 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| N5O77_RS25145 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| N5O77_RS25150 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| N5O77_RS25155 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| N5O77_RS25160 (7767) | 7767..8980 | + | 1214 | WP_172439411.1 | IS3 family transposase IS629 | Transposase |
| N5O77_RS25165 (9128) | 9128..9453 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| N5O77_RS25170 (9499) | 9499..9839 | + | 341 | Protein_9 | IS3 family transposase | - |
| N5O77_RS25175 (10434) | 10434..11621 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| N5O77_RS25180 (11618) | 11618..13558 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| N5O77_RS25185 (13562) | 13562..14932 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| N5O77_RS25190 (15406) | 15406..15600 | + | 195 | Protein_13 | IS200-IS605 family transposase IS200C | Transposase |
| N5O77_RS25195 (15729) | 15729..16670 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| N5O77_RS25200 (16905) | 16905..18294 | - | 1390 | Protein_15 | ISNCY family transposase ISKpn21 | Transposase |
| N5O77_RS25205 (18604) | 18604..18753 | - | 150 | Protein_16 | IS3 family transposase IS2 | Transposase |
| N5O77_RS25210 (18931) | 18931..20124 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| N5O77_RS25220 (23219) | 23219..23512 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| N5O77_RS25225 (23570) | 23570..23769 | - | 200 | Protein_20 | lysis protein | - |
| N5O77_RS25230 (24323) | 24323..25347 | + | 1025 | Protein_21 | integrase core domain-containing protein | - |
| N5O77_RS25235 (26658) | 26658..27773 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| N5O77_RS25240 (27913) | 27913..31572 | + | 3660 | WP_102596250.1 | Multidrug efflux ATP-binding/permease protein | VF |
| N5O77_RS25245 (31676) | 31676..32905 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| N5O77_RS25250 (32990) | 32990..33946 | + | 957 | WP_000271277.1 | Ferri-bacillibactin esterase BesA | VF |
| N5O77_RS25255 (33991) | 33991..36168 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| N5O77_RS25260 (37012) | 37012..38046 | - | 1035 | WP_001190233.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| N5O77_RS25265 (38227) | 38227..38528 | + | 302 | Protein_28 | hypothetical protein | - |
| N5O77_RS25270 (38606) | 38606..38899 | - | 294 | WP_000269327.1 | DUF6404 family protein | - |
| N5O77_RS25275 (39067) | 39067..39192 | - | 126 | Protein_30 | type II toxin-antitoxin system toxin YacB | - |
| N5O77_RS25280 (39192) | 39192..39460 | - | 269 | Protein_31 | type II toxin-antitoxin system antitoxin YacA | - |
| N5O77_RS25285 (40071) | 40071..41345 | + | 1275 | WP_000489608.1 | HlyD family secretion protein | - |
| N5O77_RS25290 (41338) | 41338..43434 | + | 2097 | WP_102596246.1 | peptidase domain-containing ABC transporter | - |
| N5O77_RS25295 (43604) | 43604..43915 | - | 312 | WP_001259758.1 | colicin V | - |
| N5O77_RS25300 (43893) | 43893..44129 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| N5O77_RS25305 (44248) | 44248..44691 | + | 444 | WP_252185664.1 | hypothetical protein | - |
| N5O77_RS25310 (44663) | 44663..45067 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| N5O77_RS25315 (45069) | 45069..45338 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| N5O77_RS25320 (45335) | 45335..46315 | + | 981 | WP_001017347.1 | NAD(P)-binding domain-containing protein | - |
| N5O77_RS25325 (46391) | 46391..46771 | + | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| N5O77_RS25330 (46768) | 46768..47115 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| N5O77_RS25335 (47165) | 47165..48438 | + | 1274 | Protein_42 | IS66 family transposase ISEc8 | Transposase |
| N5O77_RS25340 (48478) | 48478..48744 | + | 267 | Protein_43 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| N5O77_RS25345 (48791) | 48791..49182 | - | 392 | Protein_44 | peptide deformylase | - |
| N5O77_RS25350 (49291) | 49291..53424 | - | 4134 | WP_001080138.1 | Hemoglobin-binding protease hbp autotransporter | VF |
| N5O77_RS25355 (53592) | 53592..53786 | + | 195 | Protein_46 | IS91 family transposase | - |
| N5O77_RS25360 (54065) | 54065..54322 | + | 258 | Protein_47 | IS3 family transposase IS911 | Transposase |
| N5O77_RS25365 (54390) | 54390..55541 | + | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| N5O77_RS25370 (55554) | 55554..55721 | - | 168 | Protein_49 | IS3 family transposase | - |
| N5O77_RS25375 (55773) | 55773..56986 | + | 1214 | WP_172439414.1 | IS3 family transposase IS629 | Transposase |
| N5O77_RS25380 (57255) | 57255..57542 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| N5O77_RS25385 (57539) | 57539..57790 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| N5O77_RS25390 (58756) | 58756..59613 | - | 858 | WP_153789778.1 | incFII family plasmid replication initiator RepA | - |
| N5O77_RS25395 (59606) | 59606..60088 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| N5O77_RS25400 (60081) | 60081..60128 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| N5O77_RS25405 (60119) | 60119..60370 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| N5O77_RS25410 (60387) | 60387..60644 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| N5O77_RS25415 (60928) | 60928..61077 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (61121) | 61121..61182 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (61121) | 61121..61182 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (61121) | 61121..61182 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (61121) | 61121..61182 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| N5O77_RS25420 (61438) | 61438..61512 | - | 75 | Protein_59 | endonuclease | - |
| N5O77_RS25425 (61758) | 61758..61970 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| N5O77_RS25430 (62106) | 62106..62666 | - | 561 | WP_102596227.1 | fertility inhibition protein FinO | - |
| N5O77_RS25435 (62769) | 62769..63629 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| N5O77_RS25440 (63688) | 63688..64434 | - | 747 | WP_102596226.1 | conjugal transfer pilus acetylase TraX | - |
| N5O77_RS25445 (64454) | 64454..69724 | - | 5271 | WP_153789779.1 | Multifunctional conjugation protein TraI | Relaxase |
| N5O77_RS25450 (69806) | 69806..70033 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| N5O77_RS25455 (70033) | 70033..70431 | + | 399 | WP_000911333.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| N5O77_RS25460 (70440) | 70440..72593 | - | 2154 | WP_000009379.1 | type IV conjugative transfer system coupling protein TraD | - |
| N5O77_RS25465 (72846) | 72846..73577 | - | 732 | WP_000850416.1 | conjugal transfer complement resistance protein TraT | - |
| N5O77_RS25470 (73591) | 73591..74100 | - | 510 | WP_000628105.1 | conjugal transfer entry exclusion protein TraS | - |
| N5O77_RS25475 (74097) | 74097..76922 | - | 2826 | WP_001007036.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| N5O77_RS25480 (76919) | 76919..78292 | - | 1374 | WP_153789780.1 | conjugal transfer pilus assembly protein TraH | - |
| N5O77_RS25485 (78279) | 78279..78671 | - | 393 | Protein_72 | F-type conjugal transfer protein TrbF | - |
| N5O77_RS25490 (78658) | 78658..78999 | - | 342 | WP_001442101.1 | P-type conjugative transfer protein TrbJ | - |
| N5O77_RS25495 (78929) | 78929..79474 | - | 546 | WP_000059833.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| N5O77_RS25500 (79461) | 79461..79745 | - | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| N5O77_RS25505 (79826) | 79826..80101 | + | 276 | WP_001513501.1 | hypothetical protein | - |
| N5O77_RS25510 (80103) | 80103..80450 | - | 348 | WP_001287907.1 | conjugal transfer protein TrbA | - |
| N5O77_RS25515 (80466) | 80466..81209 | - | 744 | WP_261175629.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| N5O77_RS25520 (81202) | 81202..81459 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| N5O77_RS25525 (81486) | 81486..83294 | - | 1809 | WP_000821867.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| N5O77_RS25530 (83291) | 83291..83929 | - | 639 | WP_000777703.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| N5O77_RS25535 (83938) | 83938..84930 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| N5O77_RS25540 (84927) | 84927..85559 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| N5O77_RS25545 (85556) | 85556..85942 | - | 387 | WP_000099688.1 | type-F conjugative transfer system protein TrbI | - |
| N5O77_RS25550 (85939) | 85939..88566 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| N5O77_RS25555 (88726) | 88726..88947 | - | 222 | WP_001278690.1 | conjugal transfer protein TraR | - |
| N5O77_RS25560 (89082) | 89082..89597 | - | 516 | WP_000809834.1 | type IV conjugative transfer system lipoprotein TraV | - |
| N5O77_RS25565 (89594) | 89594..89845 | - | 252 | WP_001038351.1 | conjugal transfer protein TrbG | - |
| N5O77_RS25570 (89857) | 89857..90054 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| N5O77_RS25575 (90041) | 90041..90631 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| N5O77_RS25580 (90621) | 90621..92048 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| N5O77_RS25585 (92048) | 92048..92776 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| N5O77_RS25590 (92763) | 92763..93329 | - | 567 | WP_001563715.1 | type IV conjugative transfer system protein TraE | - |
| N5O77_RS25595 (93351) | 93351..93662 | - | 312 | WP_047662385.1 | type IV conjugative transfer system protein TraL | - |
| N5O77_RS25600 (93677) | 93677..94042 | - | 366 | WP_000340276.1 | type IV conjugative transfer system pilin TraA | - |
| N5O77_RS25605 (94076) | 94076..94303 | - | 228 | WP_001442099.1 | conjugal transfer relaxosome protein TraY | - |
| N5O77_RS25610 (94397) | 94397..95083 | - | 687 | WP_000332490.1 | PAS domain-containing protein | - |
| N5O77_RS25615 (95273) | 95273..95656 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| N5O77_RS25620 (95978) | 95978..96580 | + | 603 | Protein_99 | hypothetical protein | VF |
| N5O77_RS25625 (96876) | 96876..97697 | - | 822 | WP_001234468.1 | DUF932 domain-containing protein | - |
| N5O77_RS25630 (97816) | 97816..98103 | - | 288 | Protein_101 | hypothetical protein | - |
| N5O77_RS25635 (98404) | 98404..98701 | + | 298 | Protein_102 | hypothetical protein | - |
| N5O77_RS25640 (99002) | 99002..99124 | - | 123 | WP_223195199.1 | Hok/Gef family protein | Toxin Detail |
| N5O77_RS25645 (99069) | 99069..99182 | - | 114 | Protein_104 | DUF5431 family protein | - |
| - (99216) | 99216..99427 | - | 212 | NuclAT_0 | - | Antitoxin Detail |
| - (99216) | 99216..99427 | - | 212 | NuclAT_0 | - | Antitoxin Detail |
| - (99216) | 99216..99427 | - | 212 | NuclAT_0 | - | Antitoxin Detail |
| - (99216) | 99216..99427 | - | 212 | NuclAT_0 | - | Antitoxin Detail |
| N5O77_RS25650 (99372) | 99372..100158 | - | 787 | Protein_105 | plasmid SOS inhibition protein A | - |
| N5O77_RS25655 (100155) | 100155..100589 | - | 435 | WP_076838612.1 | conjugation system SOS inhibitor PsiB | - |
| N5O77_RS25660 (100644) | 100644..102602 | - | 1959 | WP_102596223.1 | ParB/RepB/Spo0J family partition protein | - |
| N5O77_RS25665 (102666) | 102666..102899 | - | 234 | WP_001553739.1 | DUF905 family protein | - |
| N5O77_RS25670 (102957) | 102957..103496 | - | 540 | WP_009426937.1 | single-stranded DNA-binding protein | - |
| N5O77_RS25675 (103797) | 103797..104222 | + | 426 | WP_147706105.1 | hypothetical protein | - |
| N5O77_RS25680 (104308) | 104308..104871 | - | 564 | WP_153789781.1 | class I SAM-dependent methyltransferase | - |
| N5O77_RS25685 (104919) | 104919..106280 | - | 1362 | WP_153789782.1 | DUF3560 domain-containing protein | - |
| N5O77_RS25690 (106332) | 106332..106562 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| N5O77_RS25695 (107079) | 107079..107332 | + | 254 | Protein_114 | hypothetical protein | - |
| N5O77_RS25700 (107556) | 107556..107738 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| N5O77_RS25705 (107738) | 107738..108199 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| N5O77_RS25710 (108199) | 108199..108624 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| N5O77_RS25715 (109026) | 109026..109997 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| N5O77_RS25720 (110258) | 110258..110470 | - | 213 | WP_000092896.1 | hypothetical protein | - |
| N5O77_RS25725 (110483) | 110483..111058 | - | 576 | WP_000343071.1 | hypothetical protein | - |
| N5O77_RS25730 (111127) | 111127..111465 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| N5O77_RS25735 (111471) | 111471..111640 | - | 170 | Protein_122 | hypothetical protein | - |
| N5O77_RS25740 (112277) | 112277..113248 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| N5O77_RS25745 (113248) | 113248..114414 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| N5O77_RS25755 (115936) | 115936..118137 | - | 2202 | WP_000973517.1 | Ferric aerobactin receptor | VF |
| N5O77_RS25760 (118163) | 118163..119496 | - | 1334 | Protein_127 | L-lysine N6-monooxygenase | VF |
| N5O77_RS25765 (119493) | 119493..121235 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| N5O77_RS25770 (121235) | 121235..122182 | - | 948 | WP_000011907.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| N5O77_RS25775 (122183) | 122183..123907 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| N5O77_RS25780 (124043) | 124043..125236 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| N5O77_RS25785 (125616) | 125616..125996 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| N5O77_RS25790 (126337) | 126337..126750 | - | 414 | Protein_133 | phosphopyruvate hydratase | - |
| N5O77_RS25795 (126748) | 126748..127005 | + | 258 | Protein_134 | transposase | - |
| N5O77_RS25800 (127239) | 127239..128096 | - | 858 | WP_153789809.1 | Manganese transport system membrane protein MntB | ARG |
| N5O77_RS25805 (128093) | 128093..128950 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| N5O77_RS25810 (128947) | 128947..129774 | - | 828 | WP_021517436.1 | putative ABC transporter ATP-binding protein | VF |
| N5O77_RS25815 (129774) | 129774..130688 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| N5O77_RS25820 (131044) | 131044..131741 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| N5O77_RS25825 (131921) | 131921..132434 | - | 514 | Protein_140 | DUF4113 domain-containing protein | - |
| N5O77_RS25830 (132495) | 132495..132599 | - | 105 | Protein_141 | AAA family ATPase | - |
| N5O77_RS25835 (132601) | 132601..132924 | - | 324 | Protein_142 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|