MGE detailed information
MGE type: Mobilizable plasmid MGE length: 128773 bp
Accession: NZ_CP103763 Location: 1..128773 Organism: Escherichia coli strain 5283 Replicon: plasmid pMB9880_1
Accession: NZ_CP103763 Location: 1..128773 Organism: Escherichia coli strain 5283 Replicon: plasmid pMB9880_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5T11_RS24775 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| M5T11_RS24780 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| M5T11_RS24785 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| M5T11_RS24790 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| M5T11_RS24795 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| M5T11_RS24805 (4785) | 4785..5954 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| M5T11_RS24810 (5987) | 5987..6115 | + | 129 | Protein_7 | IS481 family transposase | - |
| M5T11_RS24815 (6150) | 6150..6338 | - | 189 | Protein_8 | hypothetical protein | - |
| M5T11_RS24820 (6386) | 6386..7083 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| M5T11_RS24825 (7095) | 7095..7202 | + | 108 | Protein_10 | transcriptional regulator | - |
| M5T11_RS24830 (7180) | 7180..7803 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| M5T11_RS24835 (7885) | 7885..9090 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| M5T11_RS24840 (9203) | 9203..9796 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| M5T11_RS24845 (9884) | 9884..10300 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| M5T11_RS24850 (10310) | 10310..10831 | - | 522 | Protein_15 | IS4 family transposase IS10R | Transposase |
| M5T11_RS24855 (10838) | 10838..11026 | - | 189 | Protein_16 | IS1 family transposase | - |
| M5T11_RS24860 (11091) | 11091..11795 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T11_RS24865 (11841) | 11841..12488 | - | 648 | Protein_18 | IS91 family transposase ISAzo26 | Transposase |
| M5T11_RS24870 (12646) | 12646..13119 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| M5T11_RS24875 (13250) | 13250..14038 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| M5T11_RS24880 (14244) | 14244..14591 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| M5T11_RS24885 (14585) | 14585..15424 | + | 840 | WP_000259031.1 | Cell surface antigen I/II | ARG |
| M5T11_RS24890 (15552) | 15552..15755 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| M5T11_RS24895 (15911) | 15911..16276 | + | 366 | Protein_24 | chromate transporter | - |
| M5T11_RS24900 (16330) | 16330..17034 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5T11_RS24905 (17210) | 17210..17491 | - | 282 | Protein_26 | transposase zinc-binding domain-containing protein | - |
| M5T11_RS24910 (17638) | 17638..18498 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M5T11_RS24915 (18681) | 18681..19019 | - | 339 | Protein_28 | recombinase family protein | - |
| M5T11_RS24920 (19083) | 19083..19787 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T11_RS24925 (19842) | 19842..19913 | + | 72 | Protein_30 | hypothetical protein | - |
| M5T11_RS24930 (20169) | 20169..21044 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| M5T11_RS24935 (21091) | 21091..21384 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| M5T11_RS24940 (21449) | 21449..23668 | + | 2220 | Protein_33 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5T11_RS24945 (23745) | 23745..24449 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T11_RS24950 (24503) | 24503..24943 | - | 441 | Protein_35 | CatB-related O-acetyltransferase | - |
| M5T11_RS24955 (25081) | 25081..25911 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| M5T11_RS24960 (26042) | 26042..26596 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| M5T11_RS24965 (26740) | 26740..27444 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T11_RS24970 (27510) | 27510..28022 | + | 513 | Protein_39 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5T11_RS24975 (28046) | 28046..28651 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| M5T11_RS24980 (28746) | 28746..31643 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| M5T11_RS24985 (31780) | 31780..32181 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5T11_RS24990 (32114) | 32114..32371 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5T11_RS24995 (32464) | 32464..33117 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| M5T11_RS25000 (33215) | 33215..33355 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| M5T11_RS25005 (34057) | 34057..34914 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| M5T11_RS25010 (34907) | 34907..34981 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| M5T11_RS25015 (34981) | 34981..35112 | - | 132 | Protein_48 | protein CopA/IncA | - |
| M5T11_RS25020 (35343) | 35343..36884 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| M5T11_RS25025 (36899) | 36899..37645 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| M5T11_RS25030 (37805) | 37805..38059 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| M5T11_RS25035 (38356) | 38356..38490 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (38535) | 38535..38595 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (38535) | 38535..38595 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (38535) | 38535..38595 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (38535) | 38535..38595 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| M5T11_RS25040 (38562) | 38562..38848 | - | 287 | Protein_53 | DUF2726 domain-containing protein | - |
| M5T11_RS25045 (39361) | 39361..39573 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| M5T11_RS25050 (39704) | 39704..40264 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| M5T11_RS25055 (40319) | 40319..41065 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| M5T11_RS25060 (41085) | 41085..43541 | - | 2457 | Protein_57 | Multifunctional conjugation protein TraI | Relaxase |
| M5T11_RS25065 (43602) | 43602..44306 | + | 705 | WP_001067858.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5T11_RS25070 (44360) | 44360..45154 | - | 795 | Protein_59 | IS4 family transposase IS10R | Transposase |
| M5T11_RS25075 (45264) | 45264..46226 | - | 963 | Protein_60 | IS4 family transposase IS10R | Transposase |
| M5T11_RS25080 (46369) | 46369..47229 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| M5T11_RS25085 (47242) | 47242..47784 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| M5T11_RS25090 (48266) | 48266..48457 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| M5T11_RS25095 (48481) | 48481..48708 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| M5T11_RS25100 (48759) | 48759..49886 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| M5T11_RS25105 (49923) | 49923..50627 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T11_RS25110 (50749) | 50749..51654 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| M5T11_RS25115 (51651) | 51651..52889 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| M5T11_RS25120 (52889) | 52889..53473 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| M5T11_RS25125 (53966) | 53966..54730 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| M5T11_RS25130 (54870) | 54870..55574 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T11_RS25135 (55635) | 55635..56471 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| M5T11_RS25140 (56471) | 56471..57274 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| M5T11_RS25145 (57335) | 57335..58150 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| M5T11_RS25150 (58458) | 58458..59309 | - | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| M5T11_RS25155 (59296) | 59296..60015 | - | 720 | Protein_76 | helicase RepA family protein | - |
| M5T11_RS25160 (60065) | 60065..60769 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| M5T11_RS25165 (60833) | 60833..61504 | + | 672 | Protein_78 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| M5T11_RS25170 (61729) | 61729..62370 | - | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| M5T11_RS25175 (62610) | 62610..62930 | - | 321 | Protein_80 | IS1380 family transposase ISEcp1 | Transposase |
| M5T11_RS25180 (62943) | 62943..63503 | + | 561 | WP_000147567.1 | recombinase family protein | - |
| M5T11_RS25185 (63506) | 63506..65977 | + | 2472 | Protein_82 | Tn3-like element TnAs3 family transposase | - |
| M5T11_RS25190 (66124) | 66124..66984 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M5T11_RS25195 (67067) | 67067..67771 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5T11_RS25200 (67826) | 67826..70552 | - | 2727 | Protein_85 | Multifunctional conjugation protein TraI | Relaxase |
| M5T11_RS25205 (70542) | 70542..70715 | - | 174 | Protein_86 | type IV secretion system DNA-binding domain-containing protein | - |
| M5T11_RS25210 (70714) | 70714..70878 | - | 165 | Protein_87 | TraU family protein | - |
| M5T11_RS25215 (70875) | 70875..71219 | - | 345 | Protein_88 | conjugal transfer protein TraW | - |
| M5T11_RS25220 (71215) | 71215..73536 | - | 2322 | Protein_89 | type IV secretion system protein TraC | - |
| M5T11_RS25225 (73696) | 73696..73917 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| M5T11_RS25230 (74052) | 74052..74567 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M5T11_RS25235 (74567) | 74567..74878 | - | 312 | WP_001057272.1 | conjugal transfer protein TrbD | - |
| M5T11_RS25240 (74865) | 74865..75431 | - | 567 | WP_000896601.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| M5T11_RS25245 (75421) | 75421..76872 | - | 1452 | WP_000146687.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M5T11_RS25250 (76872) | 76872..77600 | - | 729 | WP_001230808.1 | type-F conjugative transfer system secretin TraK | - |
| M5T11_RS25255 (77587) | 77587..78153 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| M5T11_RS25260 (78175) | 78175..78486 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| M5T11_RS25265 (78491) | 78491..78853 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| M5T11_RS25270 (78887) | 78887..79114 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| M5T11_RS25275 (79202) | 79202..79879 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| M5T11_RS25280 (80013) | 80013..80396 | - | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M5T11_RS25285 (80727) | 80727..81329 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| M5T11_RS25290 (81626) | 81626..82447 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| M5T11_RS25295 (82566) | 82566..82853 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| M5T11_RS25300 (82878) | 82878..83084 | - | 207 | WP_024190427.1 | hypothetical protein | - |
| M5T11_RS25305 (83154) | 83154..83327 | + | 174 | Protein_106 | hypothetical protein | - |
| M5T11_RS25310 (83325) | 83325..83555 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| M5T11_RS25315 (83775) | 83775..83900 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| M5T11_RS25320 (83842) | 83842..83991 | - | 150 | Protein_109 | plasmid maintenance protein Mok | - |
| - (83977) | 83977..84015 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (83977) | 83977..84015 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (83977) | 83977..84015 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (83977) | 83977..84015 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (85455) | 85455..85557 | - | 103 | NuclAT_0 | - | - |
| - (85455) | 85455..85557 | - | 103 | NuclAT_0 | - | - |
| - (85455) | 85455..85557 | - | 103 | NuclAT_0 | - | - |
| - (85455) | 85455..85557 | - | 103 | NuclAT_0 | - | - |
| M5T11_RS25330 (85526) | 85526..86288 | - | 763 | Protein_111 | plasmid SOS inhibition protein A | - |
| M5T11_RS25335 (86285) | 86285..86719 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| M5T11_RS25340 (86774) | 86774..88732 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| M5T11_RS25345 (88798) | 88798..89031 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| M5T11_RS25350 (89094) | 89094..89591 | - | 498 | WP_042045560.1 | single-stranded DNA-binding protein | - |
| M5T11_RS25355 (89741) | 89741..91642 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| M5T11_RS25360 (92320) | 92320..92526 | - | 207 | WP_000547975.1 | hypothetical protein | - |
| M5T11_RS25365 (92767) | 92767..93024 | - | 258 | WP_023147917.1 | hypothetical protein | - |
| M5T11_RS25370 (92937) | 92937..93149 | - | 213 | WP_001348622.1 | hypothetical protein | - |
| M5T11_RS25375 (93175) | 93175..93738 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| M5T11_RS25380 (93786) | 93786..95147 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| M5T11_RS25385 (95199) | 95199..95429 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| M5T11_RS25390 (95943) | 95943..96191 | + | 249 | WP_071556315.1 | hypothetical protein | - |
| M5T11_RS25395 (96464) | 96464..96655 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| M5T11_RS25400 (96652) | 96652..97074 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| M5T11_RS25405 (97121) | 97121..97546 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| M5T11_RS25410 (97963) | 97963..98739 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| M5T11_RS25415 (98790) | 98790..99308 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| M5T11_RS25420 (99238) | 99238..99459 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| M5T11_RS25425 (99460) | 99460..100143 | - | 684 | WP_000086185.1 | DNA methylase | - |
| M5T11_RS25430 (100220) | 100220..100531 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| M5T11_RS25435 (100528) | 100528..101430 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| M5T11_RS25440 (102297) | 102297..103268 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5T11_RS25445 (103268) | 103268..104434 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| M5T11_RS25450 (105022) | 105022..105777 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| M5T11_RS25455 (106551) | 106551..107357 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| M5T11_RS25460 (107358) | 107358..107663 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| M5T11_RS25465 (107665) | 107665..107883 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| M5T11_RS25470 (108517) | 108517..108714 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| M5T11_RS25475 (108711) | 108711..108995 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| M5T11_RS25480 (109015) | 109015..110148 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| M5T11_RS25485 (110411) | 110411..113530 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| M5T11_RS25490 (113837) | 113837..114067 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M5T11_RS25495 (114064) | 114064..114480 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M5T11_RS25500 (114642) | 114642..116780 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| M5T11_RS25505 (117245) | 117245..118240 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| M5T11_RS25510 (118283) | 118283..119176 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| M5T11_RS25520 (120224) | 120224..123340 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| M5T11_RS25525 (123462) | 123462..124733 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| M5T11_RS25530 (124730) | 124730..126286 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| M5T11_RS25535 (126469) | 126469..126690 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| M5T11_RS25540 (126690) | 126690..127070 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| M5T11_RS25545 (127075) | 127075..127254 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| M5T11_RS25550 (127282) | 127282..127560 | + | 279 | Protein_155 | pdcB | - |
| M5T11_RS25555 (127565) | 127565..127978 | + | 414 | Protein_156 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|