MGE detailed information
MGE type: Conjugative plasmid MGE length: 120324 bp
Accession: NZ_CP103746 Location: 1..120324 Organism: Escherichia coli strain 3090 Replicon: plasmid pMB2791_1
Accession: NZ_CP103746 Location: 1..120324 Organism: Escherichia coli strain 3090 Replicon: plasmid pMB2791_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5T02_RS23630 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| M5T02_RS23635 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| M5T02_RS23640 (2124) | 2124..2319 | - | 196 | Protein_2 | serine/threonine protein kinase | - |
| M5T02_RS23645 (2406) | 2406..2801 | - | 396 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| M5T02_RS23650 (2866) | 2866..3570 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T02_RS23655 (3623) | 3623..4420 | - | 798 | Protein_5 | IS91 family transposase ISMno23 | Transposase |
| M5T02_RS23660 (4569) | 4569..5407 | + | 839 | Protein_6 | Streptomycin 3''-adenylyltransferase | ARG |
| M5T02_RS23665 (5492) | 5492..6313 | + | 822 | WP_000939727.1 | hypothetical protein | ARG |
| M5T02_RS23670 (6466) | 6466..7170 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T02_RS23675 (7418) | 7418..7705 | + | 288 | WP_230071785.1 | hypothetical protein | - |
| M5T02_RS23685 (9082) | 9082..9897 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| M5T02_RS23690 (9984) | 9984..10226 | + | 243 | Protein_12 | phosphoglucosamine mutase | - |
| M5T02_RS23695 (10462) | 10462..11955 | - | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| M5T02_RS23700 (12067) | 12067..12372 | - | 306 | WP_259429213.1 | HTH-type transcriptional regulator CynR | VF |
| M5T02_RS23705 (12400) | 12400..13614 | - | 1215 | WP_058657119.1 | Bicyclomycin resistance protein | ARG |
| M5T02_RS23710 (13831) | 13831..14715 | - | 885 | WP_012728215.1 | DUF3363 domain-containing protein | - |
| M5T02_RS23715 (14746) | 14746..15576 | - | 831 | Protein_17 | IS91 family transposase ISVsa3 | Transposase |
| M5T02_RS23720 (15640) | 15640..16344 | + | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| M5T02_RS23725 (16429) | 16429..16905 | - | 477 | WP_223171565.1 | hypothetical protein | - |
| M5T02_RS23730 (16839) | 16839..19790 | - | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| M5T02_RS23735 (19793) | 19793..20353 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| M5T02_RS23740 (20479) | 20479..20829 | - | 351 | WP_071830595.1 | DUF3330 domain-containing protein | - |
| M5T02_RS23745 (21032) | 21032..22045 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| M5T02_RS23750 (22190) | 22190..22687 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| M5T02_RS23755 (22799) | 22799..23089 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| M5T02_RS23760 (23095) | 23095..23933 | + | 839 | Protein_26 | Streptomycin 3''-adenylyltransferase | ARG |
| M5T02_RS23765 (24148) | 24148..25407 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| M5T02_RS23770 (25500) | 25500..26338 | + | 839 | Protein_28 | Streptomycin 3''-adenylyltransferase | ARG |
| M5T02_RS23775 (26461) | 26461..26793 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| M5T02_RS23780 (27040) | 27040..27672 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| M5T02_RS23785 (27933) | 27933..28100 | - | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| M5T02_RS23790 (28219) | 28219..30138 | - | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| M5T02_RS23795 (30154) | 30154..30270 | - | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| M5T02_RS23800 (30515) | 30515..30982 | - | 468 | Protein_34 | conjugal transfer protein | - |
| M5T02_RS23805 (31036) | 31036..31740 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T02_RS23810 (32277) | 32277..32819 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| M5T02_RS23815 (32832) | 32832..33692 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| M5T02_RS23820 (33835) | 33835..34329 | + | 495 | Protein_38 | IS4 family transposase IS10R | Transposase |
| M5T02_RS23825 (34383) | 34383..35087 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5T02_RS23830 (35155) | 35155..36453 | + | 1299 | Protein_40 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5T02_RS23835 (36487) | 36487..36987 | + | 501 | Protein_41 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5T02_RS23840 (37021) | 37021..37209 | + | 189 | Protein_42 | IS3 family transposase | - |
| M5T02_RS23845 (37284) | 37284..37571 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| M5T02_RS23850 (37568) | 37568..37819 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| M5T02_RS23855 (38785) | 38785..39642 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| M5T02_RS23860 (39635) | 39635..39709 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| M5T02_RS23865 (39941) | 39941..40198 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| M5T02_RS23870 (40466) | 40466..40615 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (40659) | 40659..40720 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (40659) | 40659..40720 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (40659) | 40659..40720 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (40659) | 40659..40720 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| M5T02_RS23875 (41062) | 41062..41274 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| M5T02_RS23880 (41409) | 41409..41969 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| M5T02_RS23885 (42024) | 42024..42767 | - | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| M5T02_RS23890 (42787) | 42787..48057 | - | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5T02_RS23895 (48057) | 48057..50237 | - | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| M5T02_RS23900 (50490) | 50490..51221 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| M5T02_RS23905 (51253) | 51253..51756 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| M5T02_RS23910 (51771) | 51771..54593 | - | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M5T02_RS23915 (54590) | 54590..55963 | - | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| M5T02_RS23920 (55963) | 55963..56325 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| M5T02_RS23925 (56255) | 56255..56800 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M5T02_RS23930 (56787) | 56787..57023 | - | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M5T02_RS23935 (57184) | 57184..57927 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| M5T02_RS23940 (57920) | 57920..58180 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| M5T02_RS23945 (58207) | 58207..60015 | - | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| M5T02_RS23950 (60012) | 60012..60650 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| M5T02_RS23955 (60659) | 60659..61651 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| M5T02_RS23960 (61648) | 61648..62280 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| M5T02_RS23965 (62277) | 62277..62663 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| M5T02_RS23970 (62660) | 62660..65287 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| M5T02_RS23975 (65447) | 65447..65668 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| M5T02_RS23980 (65803) | 65803..66318 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M5T02_RS23985 (66315) | 66315..66635 | - | 321 | WP_063078087.1 | conjugal transfer protein TrbD | - |
| M5T02_RS23990 (66622) | 66622..67209 | - | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| M5T02_RS23995 (67199) | 67199..68626 | - | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M5T02_RS24000 (68626) | 68626..69354 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| M5T02_RS24005 (69341) | 69341..69907 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| M5T02_RS24010 (69929) | 69929..70240 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| M5T02_RS24015 (70245) | 70245..70607 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| M5T02_RS24020 (70640) | 70640..71041 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| M5T02_RS24025 (71134) | 71134..71823 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| M5T02_RS24030 (72010) | 72010..72393 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M5T02_RS24035 (72714) | 72714..73316 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| M5T02_RS24040 (73613) | 73613..74434 | - | 822 | WP_072795862.1 | DUF932 domain-containing protein | - |
| M5T02_RS24045 (74556) | 74556..74843 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| M5T02_RS24050 (74868) | 74868..75074 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| M5T02_RS24055 (75144) | 75144..75317 | + | 174 | Protein_85 | hypothetical protein | - |
| M5T02_RS24060 (75315) | 75315..75545 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| M5T02_RS24065 (75765) | 75765..75890 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| M5T02_RS24070 (75832) | 75832..75981 | - | 150 | Protein_88 | plasmid maintenance protein Mok | - |
| - (75967) | 75967..76191 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (75967) | 75967..76191 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (75967) | 75967..76191 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (75967) | 75967..76191 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| M5T02_RS24075 (76003) | 76003..76191 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| M5T02_RS24080 (76160) | 76160..76922 | - | 763 | Protein_90 | plasmid SOS inhibition protein A | - |
| M5T02_RS24085 (76919) | 76919..77353 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| M5T02_RS24090 (77408) | 77408..79366 | - | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| M5T02_RS24095 (79431) | 79431..79664 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| M5T02_RS24100 (79721) | 79721..80218 | - | 498 | WP_225856491.1 | single-stranded DNA-binding protein | - |
| M5T02_RS24105 (80368) | 80368..82269 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| M5T02_RS24110 (82947) | 82947..83153 | - | 207 | WP_000275853.1 | hypothetical protein | - |
| M5T02_RS24115 (83394) | 83394..83621 | - | 228 | WP_071961421.1 | hypothetical protein | - |
| M5T02_RS24120 (83773) | 83773..84336 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| M5T02_RS24125 (84384) | 84384..85745 | - | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| M5T02_RS24130 (85797) | 85797..86027 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| M5T02_RS24135 (87062) | 87062..87253 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| M5T02_RS24140 (87250) | 87250..87672 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| M5T02_RS24145 (87719) | 87719..88144 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| M5T02_RS24150 (88721) | 88721..89833 | - | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| M5T02_RS24155 (89910) | 89910..90686 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| M5T02_RS24160 (90737) | 90737..91255 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| M5T02_RS24165 (91185) | 91185..91406 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| M5T02_RS24170 (91407) | 91407..92090 | - | 684 | WP_000086185.1 | DNA methylase | - |
| M5T02_RS24175 (92167) | 92167..92478 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| M5T02_RS24180 (92475) | 92475..93377 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| M5T02_RS24185 (93795) | 93795..94043 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| M5T02_RS24190 (94040) | 94040..94477 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| M5T02_RS24195 (94477) | 94477..95748 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| M5T02_RS24200 (95753) | 95753..96145 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| M5T02_RS24205 (96150) | 96150..97121 | - | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| M5T02_RS24210 (97343) | 97343..97987 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| M5T02_RS24215 (97981) | 97981..98256 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| M5T02_RS24220 (98408) | 98408..99184 | - | 777 | Protein_118 | site-specific integrase | - |
| M5T02_RS24225 (99181) | 99181..99687 | - | 507 | WP_001505085.1 | hypothetical protein | - |
| M5T02_RS24230 (99678) | 99678..100382 | + | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| M5T02_RS24235 (100531) | 100531..101856 | - | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| M5T02_RS24240 (101966) | 101966..102663 | + | 698 | WP_114161604.1 | IS1 family transposase IS1R | Transposase |
| M5T02_RS24245 (102764) | 102764..103045 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| M5T02_RS24250 (103147) | 103147..104040 | - | 894 | Protein_124 | IS3 family transposase ISEhe3 | Transposase |
| M5T02_RS24255 (104108) | 104108..104926 | + | 819 | Protein_125 | IS30 family transposase IS30D | Transposase |
| M5T02_RS24265 (106261) | 106261..106410 | + | 150 | Protein_127 | IS30 family transposase IS30D | Transposase |
| M5T02_RS24270 (106835) | 106835..107119 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| M5T02_RS24275 (107139) | 107139..108272 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| M5T02_RS24280 (108535) | 108535..110172 | - | 1638 | WP_223201785.1 | hypothetical protein | - |
| M5T02_RS24285 (110223) | 110223..111053 | - | 831 | WP_223201786.1 | hypothetical protein | - |
| M5T02_RS24290 (111105) | 111105..111653 | - | 549 | WP_039002808.1 | hypothetical protein | - |
| M5T02_RS24295 (111959) | 111959..112189 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M5T02_RS24300 (112186) | 112186..112602 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M5T02_RS24305 (112764) | 112764..114902 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| M5T02_RS24310 (115367) | 115367..116362 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| M5T02_RS24315 (116405) | 116405..117298 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| M5T02_RS24325 (118280) | 118280..118438 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| M5T02_RS24330 (118597) | 118597..119569 | - | 973 | Protein_140 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|