MGE detailed information
MGE type: Conjugative plasmid MGE length: 111444 bp
Accession: NZ_CP101878 Location: 1..111444 Organism: Klebsiella pneumoniae strain KPA1 Replicon: plasmid p1
Accession: NZ_CP101878 Location: 1..111444 Organism: Klebsiella pneumoniae strain KPA1 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NNX43_RS25755 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| NNX43_RS25760 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| NNX43_RS25765 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| NNX43_RS25770 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NNX43_RS25775 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| NNX43_RS25780 (3449) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| NNX43_RS25785 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| NNX43_RS25790 (4814) | 4814..5107 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| NNX43_RS25795 (5213) | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NNX43_RS25800 (5488) | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| NNX43_RS25805 (6426) | 6426..7123 | + | 698 | WP_151884388.1 | IS1 family transposase IS1X2 | Transposase |
| NNX43_RS25810 (7138) | 7138..8301 | + | 1164 | Protein_11 | IS4 family transposase IS10R | Transposase |
| NNX43_RS25815 (8311) | 8311..8727 | - | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| NNX43_RS25820 (8815) | 8815..9408 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| NNX43_RS25825 (9521) | 9521..10726 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| NNX43_RS25830 (10808) | 10808..11431 | + | 624 | WP_168799663.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| NNX43_RS25835 (11409) | 11409..12095 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| NNX43_RS25840 (12103) | 12103..12489 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| NNX43_RS25845 (12482) | 12482..12745 | - | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| NNX43_RS25855 (13494) | 13494..13769 | + | 276 | Protein_20 | CatA-like O-acetyltransferase | - |
| NNX43_RS25860 (13970) | 13970..14347 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| NNX43_RS25865 (14414) | 14414..17380 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NNX43_RS25870 (17383) | 17383..17943 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| NNX43_RS25875 (18069) | 18069..18419 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| NNX43_RS25880 (18622) | 18622..19635 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| NNX43_RS25885 (19780) | 19780..20277 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
| NNX43_RS25890 (20389) | 20389..20679 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| NNX43_RS25895 (20685) | 20685..21523 | + | 839 | Protein_28 | Streptomycin 3''-adenylyltransferase | ARG |
| NNX43_RS25900 (21640) | 21640..21987 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NNX43_RS25905 (21981) | 21981..22820 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| NNX43_RS25910 (23225) | 23225..24766 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| NNX43_RS25915 (25000) | 25000..25134 | - | 135 | Protein_32 | IS30 family transposase | - |
| NNX43_RS25920 (25299) | 25299..26003 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NNX43_RS25925 (26069) | 26069..26614 | + | 546 | Protein_34 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NNX43_RS25930 (26650) | 26650..27065 | - | 416 | Protein_35 | IS1 family transposase | - |
| NNX43_RS25935 (27314) | 27314..27715 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NNX43_RS25940 (27648) | 27648..27905 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NNX43_RS25945 (27998) | 27998..28651 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NNX43_RS25950 (29575) | 29575..32592 | + | 3018 | WP_021740570.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| NNX43_RS25955 (32831) | 32831..33688 | - | 858 | WP_000130948.1 | incFII family plasmid replication initiator RepA | - |
| NNX43_RS25960 (33681) | 33681..33755 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| NNX43_RS25965 (33991) | 33991..34248 | - | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| NNX43_RS25970 (34653) | 34653..35675 | + | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| NNX43_RS25975 (36147) | 36147..36500 | + | 354 | WP_000005489.1 | hypothetical protein | - |
| NNX43_RS25980 (36913) | 36913..37491 | - | 579 | WP_032147503.1 | DUF2726 domain-containing protein | - |
| NNX43_RS25985 (37524) | 37524..38221 | + | 698 | WP_250164203.1 | IS1-like element IS1B family transposase | - |
| NNX43_RS25990 (38300) | 38300..39006 | + | 707 | WP_228719446.1 | IS1 family transposase | - |
| NNX43_RS25995 (39307) | 39307..39519 | - | 213 | WP_005012601.1 | hypothetical protein | - |
| NNX43_RS26000 (39652) | 39652..40212 | - | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| NNX43_RS26005 (40267) | 40267..41013 | - | 747 | WP_094083868.1 | conjugal transfer pilus acetylase TraX | - |
| NNX43_RS26010 (41033) | 41033..42223 | - | 1191 | Protein_51 | Multifunctional conjugation protein TraI | Relaxase |
| NNX43_RS26015 (42328) | 42328..42960 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| NNX43_RS26020 (42957) | 42957..43343 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| NNX43_RS26025 (43340) | 43340..45967 | - | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| NNX43_RS26030 (46127) | 46127..46348 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| NNX43_RS26035 (46483) | 46483..46998 | - | 516 | WP_256689472.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NNX43_RS26040 (46995) | 46995..47246 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| NNX43_RS26045 (47239) | 47239..47559 | - | 321 | Protein_58 | conjugal transfer protein TrbD | - |
| NNX43_RS26050 (47546) | 47546..48073 | - | 528 | WP_005012539.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NNX43_RS26055 (48117) | 48117..48683 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| NNX43_RS26060 (48705) | 48705..49016 | - | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| NNX43_RS26065 (49031) | 49031..49396 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| NNX43_RS26070 (49439) | 49439..49654 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| NNX43_RS26075 (49790) | 49790..50437 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| NNX43_RS26080 (50628) | 50628..51011 | - | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NNX43_RS26085 (51381) | 51381..51953 | + | 573 | WP_000949660.1 | hypothetical protein | VF |
| NNX43_RS26090 (52249) | 52249..53070 | - | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| NNX43_RS26095 (53189) | 53189..53476 | - | 288 | WP_000107242.1 | hypothetical protein | - |
| NNX43_RS26100 (53501) | 53501..53707 | - | 207 | WP_000275854.1 | hypothetical protein | - |
| NNX43_RS26105 (53777) | 53777..54074 | + | 298 | Protein_70 | hypothetical protein | - |
| NNX43_RS26110 (54375) | 54375..54500 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | - |
| NNX43_RS26115 (54442) | 54442..54591 | - | 150 | Protein_72 | DUF5431 family protein | - |
| - (54598) | 54598..54796 | - | 199 | NuclAT_0 | - | - |
| - (54598) | 54598..54796 | - | 199 | NuclAT_0 | - | - |
| - (54598) | 54598..54796 | - | 199 | NuclAT_0 | - | - |
| - (54598) | 54598..54796 | - | 199 | NuclAT_0 | - | - |
| NNX43_RS26120 (55025) | 55025..55342 | + | 318 | Protein_73 | IS110 family transposase IS1618 | Transposase |
| NNX43_RS26125 (55631) | 55631..55882 | - | 252 | Protein_74 | iron-containing alcohol dehydrogenase | - |
| NNX43_RS26130 (55967) | 55967..56590 | - | 624 | WP_000912556.1 | ion channel | - |
| NNX43_RS26140 (57360) | 57360..57464 | + | 105 | Protein_77 | thiosulfate reductase cytochrome B subunit | - |
| NNX43_RS26145 (57710) | 57710..59104 | - | 1395 | WP_001037799.1 | carbohydrate porin | - |
| NNX43_RS26150 (59299) | 59299..60732 | - | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| NNX43_RS26155 (60729) | 60729..62006 | - | 1278 | WP_001083369.1 | MFS transporter | - |
| NNX43_RS26160 (62069) | 62069..64195 | - | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| NNX43_RS26165 (64291) | 64291..65301 | - | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| NNX43_RS26170 (65459) | 65459..66217 | - | 759 | Protein_83 | site-specific integrase | - |
| NNX43_RS26175 (66308) | 66308..67536 | + | 1229 | WP_152924612.1 | IS3 family transposase IS2 | Transposase |
| NNX43_RS26180 (67521) | 67521..68090 | + | 570 | WP_089634947.1 | hypothetical protein | - |
| NNX43_RS26185 (69021) | 69021..69296 | - | 276 | WP_071780182.1 | hypothetical protein | - |
| NNX43_RS26190 (69191) | 69191..69421 | - | 231 | WP_021526513.1 | hypothetical protein | - |
| NNX43_RS26195 (69447) | 69447..70010 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| NNX43_RS26200 (70058) | 70058..71419 | - | 1362 | WP_094307953.1 | DUF3560 domain-containing protein | - |
| NNX43_RS26205 (71471) | 71471..71701 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| NNX43_RS26210 (72736) | 72736..72927 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| NNX43_RS26215 (72924) | 72924..73346 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| NNX43_RS26220 (73393) | 73393..73818 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| NNX43_RS26225 (74235) | 74235..75011 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| NNX43_RS26230 (75062) | 75062..75580 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| NNX43_RS26235 (75510) | 75510..75731 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| NNX43_RS26240 (75732) | 75732..76415 | - | 684 | WP_000086185.1 | DNA methylase | - |
| NNX43_RS26245 (76492) | 76492..76803 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| NNX43_RS26250 (76800) | 76800..77702 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| NNX43_RS26255 (78569) | 78569..79540 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NNX43_RS26260 (79540) | 79540..80706 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| NNX43_RS26265 (81294) | 81294..82049 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| NNX43_RS26270 (82823) | 82823..83629 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| NNX43_RS26275 (83630) | 83630..83935 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NNX43_RS26280 (83937) | 83937..84155 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NNX43_RS26285 (84789) | 84789..84986 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| NNX43_RS26290 (84983) | 84983..85267 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| NNX43_RS26295 (85287) | 85287..86420 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| NNX43_RS26300 (86683) | 86683..89802 | - | 3120 | WP_001553851.1 | hypothetical protein | - |
| NNX43_RS26305 (90109) | 90109..90339 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NNX43_RS26310 (90336) | 90336..90752 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NNX43_RS26315 (90914) | 90914..93052 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| NNX43_RS26320 (93517) | 93517..94512 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| NNX43_RS26325 (94555) | 94555..95448 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| NNX43_RS26335 (96496) | 96496..99612 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| NNX43_RS26340 (99734) | 99734..101005 | - | 1272 | WP_048266692.1 | restriction endonuclease subunit S | - |
| NNX43_RS26345 (101002) | 101002..102558 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| NNX43_RS26350 (102741) | 102741..102962 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| NNX43_RS26355 (102962) | 102962..103342 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| NNX43_RS26360 (103347) | 103347..103526 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| NNX43_RS26365 (103554) | 103554..103832 | + | 279 | Protein_122 | pdcB | - |
| NNX43_RS26370 (103837) | 103837..104250 | + | 414 | Protein_123 | IS3 family transposase ISLad1 | Transposase |
| NNX43_RS26375 (104200) | 104200..104535 | - | 336 | WP_169329198.1 | type I deoxyribonuclease HsdR | - |
| NNX43_RS26380 (104745) | 104745..105725 | - | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| NNX43_RS26385 (105969) | 105969..107372 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| NNX43_RS26390 (107359) | 107359..108291 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| NNX43_RS26395 (108400) | 108400..108729 | - | 330 | Protein_128 | TOBE domain-containing protein | - |
| NNX43_RS26405 (109719) | 109719..110689 | - | 971 | Protein_130 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|