MGE detailed information
MGE type: Conjugative plasmid MGE length: 122198 bp
Accession: NZ_CP101667 Location: 1..122198 Organism: Escherichia coli strain M171-1 Replicon: plasmid pM171-1.1
Accession: NZ_CP101667 Location: 1..122198 Organism: Escherichia coli strain M171-1 Replicon: plasmid pM171-1.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NO473_RS22225 (1001) | 1001..1564 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| NO473_RS22230 (1716) | 1716..1943 | + | 228 | WP_071961421.1 | hypothetical protein | - |
| NO473_RS22235 (2184) | 2184..2390 | + | 207 | WP_000275853.1 | hypothetical protein | - |
| NO473_RS22240 (2416) | 2416..2955 | + | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| NO473_RS22245 (3012) | 3012..3245 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| NO473_RS22250 (3310) | 3310..5268 | + | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| NO473_RS22255 (5323) | 5323..5757 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| NO473_RS22260 (5754) | 5754..6516 | + | 763 | Protein_8 | plasmid SOS inhibition protein A | - |
| NO473_RS22265 (6485) | 6485..6673 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (6485) | 6485..6709 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (6485) | 6485..6709 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (6485) | 6485..6709 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (6485) | 6485..6709 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| NO473_RS22270 (6695) | 6695..6844 | + | 150 | Protein_10 | plasmid maintenance protein Mok | - |
| NO473_RS22275 (6786) | 6786..6911 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NO473_RS22280 (7131) | 7131..7361 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| NO473_RS22285 (7359) | 7359..7532 | - | 174 | Protein_13 | hypothetical protein | - |
| NO473_RS22290 (7602) | 7602..7808 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| NO473_RS22295 (7833) | 7833..8120 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| NO473_RS22300 (8242) | 8242..9063 | + | 822 | WP_072795862.1 | DUF932 domain-containing protein | - |
| NO473_RS22305 (9360) | 9360..9962 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| NO473_RS22310 (10281) | 10281..10664 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NO473_RS22315 (10851) | 10851..11540 | + | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| NO473_RS22320 (11633) | 11633..12034 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| NO473_RS22325 (12067) | 12067..12429 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| NO473_RS22330 (12434) | 12434..12745 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NO473_RS22335 (12767) | 12767..13333 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NO473_RS22340 (13320) | 13320..14048 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NO473_RS22345 (14048) | 14048..15475 | + | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NO473_RS22350 (15465) | 15465..16052 | + | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NO473_RS22355 (16039) | 16039..16359 | + | 321 | WP_063078087.1 | conjugal transfer protein TrbD | - |
| NO473_RS22360 (16356) | 16356..16871 | + | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NO473_RS22365 (17006) | 17006..17227 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| NO473_RS22370 (17387) | 17387..20014 | + | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| NO473_RS22375 (20011) | 20011..20397 | + | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| NO473_RS22380 (20394) | 20394..21026 | + | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| NO473_RS22385 (21023) | 21023..22015 | + | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| NO473_RS22390 (22024) | 22024..22662 | + | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NO473_RS22395 (22659) | 22659..24467 | + | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NO473_RS22400 (24494) | 24494..24754 | + | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| NO473_RS22405 (24747) | 24747..25490 | + | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NO473_RS22410 (25651) | 25651..25887 | + | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NO473_RS22415 (25874) | 25874..26419 | + | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NO473_RS22420 (26349) | 26349..26711 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| NO473_RS22425 (26711) | 26711..28084 | + | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| NO473_RS22430 (28081) | 28081..30903 | + | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NO473_RS22435 (30918) | 30918..31421 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| NO473_RS22440 (31474) | 31474..32184 | + | 711 | WP_045227890.1 | conjugal transfer complement resistance protein TraT | - |
| NO473_RS22445 (32437) | 32437..34626 | + | 2190 | WP_039002212.1 | type IV conjugative transfer system coupling protein TraD | - |
| NO473_RS22450 (34626) | 34626..39896 | + | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| NO473_RS22455 (39916) | 39916..40659 | + | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| NO473_RS22460 (40714) | 40714..41274 | + | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| NO473_RS22465 (41409) | 41409..41621 | + | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| - (41963) | 41963..42024 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (41963) | 41963..42024 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (41963) | 41963..42024 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (41963) | 41963..42024 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| NO473_RS22470 (42068) | 42068..42217 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| NO473_RS22475 (42485) | 42485..42742 | + | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| NO473_RS22480 (42974) | 42974..43048 | + | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| NO473_RS22485 (43041) | 43041..43898 | + | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| NO473_RS22490 (44864) | 44864..45115 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| NO473_RS22495 (45112) | 45112..45399 | + | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NO473_RS22500 (45474) | 45474..45662 | - | 189 | Protein_56 | IS3 family transposase | - |
| NO473_RS22505 (45696) | 45696..46196 | - | 501 | Protein_57 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NO473_RS22510 (46230) | 46230..49234 | - | 3005 | Protein_58 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NO473_RS22515 (49398) | 49398..49955 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NO473_RS22520 (50138) | 50138..50998 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NO473_RS22525 (51256) | 51256..52047 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| NO473_RS22530 (52516) | 52516..52761 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| NO473_RS22535 (52799) | 52799..53662 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| NO473_RS22540 (53808) | 53808..54059 | - | 252 | Protein_64 | hypothetical protein | - |
| NO473_RS22545 (54111) | 54111..54815 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NO473_RS22550 (54966) | 54966..55781 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| NO473_RS22555 (55971) | 55971..56675 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NO473_RS22560 (56784) | 56784..57041 | - | 258 | WP_231363335.1 | hypothetical protein | - |
| NO473_RS22565 (57143) | 57143..58653 | - | 1511 | Protein_69 | Tn3-like element TnAs1 family transposase | - |
| NO473_RS22570 (58719) | 58719..59423 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NO473_RS22575 (59671) | 59671..59958 | + | 288 | WP_230071785.1 | hypothetical protein | - |
| NO473_RS22585 (61335) | 61335..62150 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| NO473_RS22590 (62237) | 62237..62479 | + | 243 | Protein_74 | phosphoglucosamine mutase | - |
| NO473_RS22595 (62715) | 62715..64208 | - | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| NO473_RS22600 (64320) | 64320..64625 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
| NO473_RS22605 (64653) | 64653..65867 | - | 1215 | WP_058657119.1 | Bicyclomycin resistance protein | ARG |
| NO473_RS22610 (66084) | 66084..66968 | - | 885 | WP_012728215.1 | DUF3363 domain-containing protein | - |
| NO473_RS22615 (66999) | 66999..67829 | - | 831 | Protein_79 | IS91 family transposase ISVsa3 | Transposase |
| NO473_RS22620 (67893) | 67893..68597 | + | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| NO473_RS22625 (68682) | 68682..69158 | - | 477 | WP_223171565.1 | hypothetical protein | - |
| NO473_RS22630 (69092) | 69092..72043 | - | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NO473_RS22635 (72046) | 72046..72606 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| NO473_RS22640 (72732) | 72732..73184 | - | 453 | WP_223277096.1 | DUF3330 domain-containing protein | - |
| NO473_RS22645 (73285) | 73285..74298 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| NO473_RS22650 (74443) | 74443..74940 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
| NO473_RS22655 (75052) | 75052..75342 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| NO473_RS22660 (75348) | 75348..76186 | + | 839 | Protein_88 | Streptomycin 3''-adenylyltransferase | ARG |
| NO473_RS22665 (76401) | 76401..77660 | + | 1260 | WP_000095725.1 | chloramphenicol efflux MFS transporter CmlA1 | ARG |
| NO473_RS22670 (77753) | 77753..78591 | + | 839 | Protein_90 | Streptomycin 3''-adenylyltransferase | ARG |
| NO473_RS22675 (78714) | 78714..79046 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| NO473_RS22680 (79293) | 79293..79925 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| NO473_RS22685 (80186) | 80186..80353 | - | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| NO473_RS22690 (80472) | 80472..82391 | - | 1920 | WP_025989258.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| NO473_RS22695 (82407) | 82407..82523 | - | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| NO473_RS22700 (82768) | 82768..83235 | - | 468 | Protein_96 | conjugal transfer protein | - |
| NO473_RS22705 (83289) | 83289..83993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NO473_RS22710 (84056) | 84056..84466 | + | 411 | Protein_98 | IS3 family transposase ISEhe3 | Transposase |
| NO473_RS22715 (84553) | 84553..84748 | + | 196 | Protein_99 | serine/threonine protein kinase | - |
| NO473_RS22720 (84869) | 84869..85609 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| NO473_RS22725 (85894) | 85894..86871 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| NO473_RS22730 (87627) | 87627..88599 | + | 973 | Protein_102 | hypothetical protein | - |
| NO473_RS22735 (88758) | 88758..88916 | - | 159 | WP_228955855.1 | abortive infection family protein | - |
| NO473_RS22740 (89064) | 89064..89761 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| NO473_RS22745 (89898) | 89898..90791 | - | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| NO473_RS22750 (90834) | 90834..91829 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| NO473_RS22755 (92294) | 92294..94432 | + | 2139 | WP_039002805.1 | AAA family ATPase | - |
| NO473_RS22760 (94594) | 94594..95010 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NO473_RS22765 (95007) | 95007..95237 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NO473_RS22770 (95543) | 95543..96091 | + | 549 | WP_039002808.1 | hypothetical protein | - |
| NO473_RS22775 (96143) | 96143..96973 | + | 831 | WP_223201786.1 | hypothetical protein | - |
| NO473_RS22780 (97024) | 97024..98661 | + | 1638 | WP_223201785.1 | hypothetical protein | - |
| NO473_RS22785 (98924) | 98924..100057 | + | 1134 | Protein_113 | DUF3800 domain-containing protein | - |
| NO473_RS22790 (100077) | 100077..100361 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| NO473_RS22795 (100626) | 100626..101822 | - | 1197 | Protein_115 | IS91 family transposase IS1294 | Transposase |
| NO473_RS22800 (101832) | 101832..102020 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| NO473_RS22805 (102109) | 102109..102240 | - | 132 | WP_256168549.1 | hypothetical protein | - |
| NO473_RS22810 (102471) | 102471..102620 | - | 150 | Protein_118 | IS30 family transposase IS30D | Transposase |
| NO473_RS22815 (102699) | 102699..103912 | + | 1214 | WP_162841971.1 | IS3 family transposase IS629 | Transposase |
| NO473_RS22820 (103955) | 103955..104773 | - | 819 | Protein_120 | IS30 family transposase IS30D | Transposase |
| NO473_RS22825 (104841) | 104841..105734 | + | 894 | Protein_121 | IS3 family transposase ISEhe3 | Transposase |
| NO473_RS22830 (105836) | 105836..106117 | + | 282 | WP_000639434.1 | hypothetical protein | - |
| NO473_RS22840 (107025) | 107025..108350 | + | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| NO473_RS22845 (108499) | 108499..109203 | - | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| NO473_RS22850 (109194) | 109194..109700 | + | 507 | WP_001505085.1 | hypothetical protein | - |
| NO473_RS22855 (109697) | 109697..110473 | + | 777 | Protein_127 | site-specific integrase | - |
| NO473_RS22860 (110625) | 110625..110900 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| NO473_RS22865 (110894) | 110894..111538 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| NO473_RS22870 (111760) | 111760..112731 | + | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| NO473_RS22875 (112736) | 112736..113128 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| NO473_RS22880 (113133) | 113133..114404 | - | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| NO473_RS22885 (114404) | 114404..114841 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NO473_RS22890 (114838) | 114838..115086 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| NO473_RS22895 (115504) | 115504..116406 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| NO473_RS22900 (116403) | 116403..116714 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| NO473_RS22905 (116791) | 116791..117474 | + | 684 | WP_000086185.1 | DNA methylase | - |
| NO473_RS22910 (117475) | 117475..117696 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| NO473_RS22915 (117626) | 117626..118144 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| NO473_RS22920 (118195) | 118195..118971 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| NO473_RS22925 (119388) | 119388..119813 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| NO473_RS22930 (119860) | 119860..120282 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| NO473_RS22935 (120279) | 120279..120470 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| NO473_RS22940 (121505) | 121505..121735 | + | 231 | WP_000218642.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|