MGE detailed information
MGE type: Conjugative plasmid MGE length: 115682 bp
Accession: NZ_CP101270 Location: 1..115682 Organism: Escherichia coli strain EC21Z-048 Replicon: plasmid pEC21Z048-116K
Accession: NZ_CP101270 Location: 1..115682 Organism: Escherichia coli strain EC21Z-048 Replicon: plasmid pEC21Z048-116K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML18_RS23340 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| NML18_RS23345 (1263) | 1263..2003 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| NML18_RS23350 (2124) | 2124..2306 | - | 183 | WP_044796127.1 | hypothetical protein | - |
| NML18_RS23355 (2373) | 2373..2663 | - | 291 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NML18_RS23360 (2650) | 2650..2918 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| NML18_RS23370 (4549) | 4549..4683 | + | 135 | Protein_6 | FaeA/PapI family transcriptional regulator | - |
| NML18_RS23375 (4806) | 4806..5056 | + | 251 | Protein_7 | polysaccharide deacetylase family protein | - |
| NML18_RS23380 (5151) | 5151..5489 | + | 339 | WP_228395588.1 | group II intron maturase-specific domain-containing protein | - |
| NML18_RS23385 (5557) | 5557..5731 | + | 175 | Protein_9 | transposase domain-containing protein | - |
| NML18_RS23390 (5926) | 5926..6939 | - | 1014 | WP_137503276.1 | sulfite reductase subunit C | - |
| NML18_RS23395 (6950) | 6950..7768 | - | 819 | WP_137503277.1 | anaerobic sulfite reductase subunit AsrB | - |
| NML18_RS23400 (7772) | 7772..8815 | - | 1044 | WP_137503278.1 | anaerobic sulfite reductase subunit AsrA | - |
| NML18_RS23405 (9152) | 9152..9790 | + | 639 | WP_254837459.1 | type 1 fimbrial protein | - |
| NML18_RS23410 (9828) | 9828..10565 | + | 738 | WP_202376135.1 | Chaperone protein FocC | VF |
| NML18_RS23415 (10573) | 10573..11130 | + | 558 | WP_254837460.1 | type 1 fimbrial protein | - |
| NML18_RS23420 (11162) | 11162..11728 | + | 567 | WP_053285701.1 | fimbrial protein | - |
| NML18_RS23425 (11776) | 11776..12432 | + | 657 | WP_247183519.1 | molecular chaperone | - |
| NML18_RS23430 (12377) | 12377..13168 | + | 792 | WP_106141718.1 | molecular chaperone | - |
| NML18_RS23435 (13172) | 13172..15784 | + | 2613 | WP_254837461.1 | Outer membrane usher protein FimD | VF |
| NML18_RS23440 (15804) | 15804..17033 | + | 1230 | WP_254837462.1 | hypothetical protein | - |
| NML18_RS23445 (17367) | 17367..18116 | + | 750 | WP_053285698.1 | EAL domain-containing protein | - |
| NML18_RS23450 (18161) | 18161..18991 | - | 831 | WP_012565223.1 | HTH-type transcriptional activator RhaR | VF |
| NML18_RS23455 (19087) | 19087..20295 | - | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| NML18_RS23460 (20614) | 20614..21498 | + | 885 | WP_000942222.1 | helix-turn-helix domain-containing protein | - |
| NML18_RS23465 (21781) | 21781..22022 | - | 242 | Protein_25 | hypothetical protein | - |
| NML18_RS23470 (22082) | 22082..22524 | + | 443 | Protein_26 | IS3 family transposase ISEc25 | Transposase |
| NML18_RS23475 (22709) | 22709..22939 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NML18_RS23480 (22936) | 22936..23352 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NML18_RS23485 (23514) | 23514..24731 | - | 1218 | WP_254837472.1 | IS66 family transposase IS679 | Transposase |
| NML18_RS23490 (24762) | 24762..24989 | - | 228 | WP_000993919.1 | IS66 family transposase IS679 | Transposase |
| NML18_RS23495 (25062) | 25062..25223 | + | 162 | WP_001384894.1 | hypothetical protein | - |
| NML18_RS23500 (25595) | 25595..26404 | - | 810 | Protein_32 | Diacetyl reductase [(S)-acetoin forming] | VF |
| NML18_RS23505 (26553) | 26553..26771 | + | 219 | WP_001292878.1 | hypothetical protein | - |
| NML18_RS23510 (26814) | 26814..27911 | + | 1098 | WP_242425796.1 | choloylglycine hydrolase family protein | - |
| NML18_RS23515 (27994) | 27994..29646 | + | 1653 | WP_012565217.1 | NAD-dependent malic enzyme | - |
| NML18_RS23520 (29694) | 29694..30233 | + | 540 | Protein_36 | anion permease | - |
| NML18_RS23525 (30340) | 30340..31548 | + | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| NML18_RS23530 (31545) | 31545..32510 | + | 966 | WP_254837463.1 | DASS family sodium-coupled anion symporter | - |
| NML18_RS23535 (32655) | 32655..33635 | + | 981 | WP_000019402.1 | IS5 family transposase IS5D | Transposase |
| NML18_RS23540 (33985) | 33985..34354 | - | 370 | Protein_40 | resolvase | - |
| NML18_RS23545 (34378) | 34378..34780 | - | 403 | Protein_41 | transposase | - |
| NML18_RS23550 (34867) | 34867..35613 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| NML18_RS23555 (35628) | 35628..37169 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| NML18_RS23560 (37780) | 37780..38088 | + | 309 | WP_254837464.1 | hypothetical protein | - |
| NML18_RS23565 (38205) | 38205..38339 | + | 135 | Protein_45 | IS3 family transposase ISCARN101 | Transposase |
| NML18_RS23570 (38751) | 38751..38891 | + | 141 | Protein_46 | transposase | - |
| NML18_RS23575 (39108) | 39108..40784 | - | 1677 | WP_254837465.1 | hypothetical protein | - |
| NML18_RS23580 (41370) | 41370..41646 | - | 277 | Protein_48 | hypothetical protein | - |
| NML18_RS23585 (41785) | 41785..42549 | - | 765 | WP_053285766.1 | hypothetical protein | VF |
| NML18_RS23590 (42580) | 42580..43377 | - | 798 | WP_254837466.1 | hypothetical protein | VF |
| NML18_RS23595 (43569) | 43569..43829 | - | 261 | WP_254837467.1 | hypothetical protein | - |
| NML18_RS23600 (43810) | 43810..44346 | - | 537 | WP_254837468.1 | hypothetical protein | - |
| NML18_RS23605 (44568) | 44568..45344 | - | 777 | WP_254837469.1 | fimbrial protein | - |
| NML18_RS23610 (45534) | 45534..46025 | - | 492 | WP_053285762.1 | hypothetical protein | VF |
| NML18_RS23615 (46061) | 46061..46837 | - | 777 | WP_001697781.1 | Chaperone protein FaeE | VF |
| NML18_RS23620 (46830) | 46830..49268 | - | 2439 | WP_254837470.1 | Outer membrane usher protein YraJ | VF |
| NML18_RS23625 (49280) | 49280..49825 | - | 546 | WP_112912633.1 | hypothetical protein | VF |
| NML18_RS23630 (49825) | 49825..50148 | - | 324 | WP_000431569.1 | hypothetical protein | VF |
| NML18_RS23635 (50618) | 50618..50809 | + | 192 | WP_032174713.1 | P fimbrial regulatory protein KS71A | VF |
| NML18_RS23640 (50964) | 50964..51329 | + | 366 | WP_254837471.1 | hypothetical protein | - |
| NML18_RS23645 (51329) | 51329..51424 | + | 96 | Protein_61 | IS91 family transposase ISEc37 | Transposase |
| NML18_RS23650 (51474) | 51474..51755 | - | 282 | WP_000780224.1 | helix-turn-helix transcriptional regulator | - |
| NML18_RS23655 (51736) | 51736..52065 | - | 330 | WP_009309978.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NML18_RS23660 (53001) | 53001..53858 | - | 858 | WP_227452093.1 | incFII family plasmid replication initiator RepA | - |
| NML18_RS23665 (53851) | 53851..54333 | - | 483 | WP_001443034.1 | hypothetical protein | - |
| NML18_RS23670 (54326) | 54326..54400 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| NML18_RS23675 (54634) | 54634..54891 | - | 258 | WP_000083834.1 | replication regulatory protein RepA | - |
| NML18_RS23680 (55175) | 55175..55324 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (55368) | 55368..55429 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (55368) | 55368..55429 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (55368) | 55368..55429 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (55368) | 55368..55429 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| NML18_RS23685 (55725) | 55725..56036 | + | 312 | WP_000802277.1 | hypothetical protein | - |
| NML18_RS23690 (56217) | 56217..56303 | - | 87 | Protein_70 | endonuclease | - |
| NML18_RS23695 (56501) | 56501..56689 | - | 189 | WP_001490801.1 | hypothetical protein | - |
| NML18_RS23700 (56824) | 56824..57384 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| NML18_RS23705 (57439) | 57439..58185 | - | 747 | WP_000205776.1 | conjugal transfer pilus acetylase TraX | - |
| NML18_RS23710 (58205) | 58205..63475 | - | 5271 | WP_253175893.1 | Multifunctional conjugation protein TraI | Relaxase |
| NML18_RS23715 (63557) | 63557..63784 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| NML18_RS23720 (63784) | 63784..64182 | + | 399 | WP_000911324.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NML18_RS23725 (64191) | 64191..66344 | - | 2154 | WP_000009350.1 | type IV conjugative transfer system coupling protein TraD | - |
| NML18_RS23730 (66597) | 66597..67307 | - | 711 | WP_042032882.1 | conjugal transfer complement resistance protein TraT | - |
| NML18_RS23735 (67353) | 67353..67874 | - | 522 | WP_000632670.1 | conjugal transfer entry exclusion protein TraS | - |
| NML18_RS23740 (67907) | 67907..70723 | - | 2817 | WP_001007052.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NML18_RS23745 (70720) | 70720..72093 | - | 1374 | WP_021553026.1 | conjugal transfer pilus assembly protein TraH | - |
| NML18_RS23750 (72080) | 72080..72472 | - | 393 | WP_040072248.1 | F-type conjugal transfer protein TrbF | - |
| NML18_RS23755 (72459) | 72459..72800 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| NML18_RS23760 (72730) | 72730..73275 | - | 546 | WP_186159624.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NML18_RS23765 (73262) | 73262..73546 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NML18_RS23770 (73627) | 73627..73941 | + | 315 | WP_000415566.1 | protein ArtA | - |
| NML18_RS23775 (73943) | 73943..74290 | - | 348 | WP_001287913.1 | conjugal transfer protein TrbA | - |
| NML18_RS23780 (74306) | 74306..75049 | - | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NML18_RS23785 (75042) | 75042..75299 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| NML18_RS23790 (75326) | 75326..77134 | - | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NML18_RS23795 (77131) | 77131..77769 | - | 639 | WP_000777688.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NML18_RS23800 (77778) | 77778..78770 | - | 993 | WP_254837456.1 | conjugal transfer pilus assembly protein TraU | - |
| NML18_RS23805 (78767) | 78767..79399 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| NML18_RS23810 (79396) | 79396..79782 | - | 387 | WP_000097320.1 | type-F conjugative transfer system protein TrbI | - |
| NML18_RS23815 (79779) | 79779..82406 | - | 2628 | WP_186159626.1 | type IV secretion system protein TraC | - |
| NML18_RS23820 (82566) | 82566..82787 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| NML18_RS23825 (82922) | 82922..83437 | - | 516 | WP_186159627.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NML18_RS23830 (83434) | 83434..83685 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| NML18_RS23835 (83697) | 83697..83894 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| NML18_RS23840 (83881) | 83881..84471 | - | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NML18_RS23845 (84461) | 84461..85888 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NML18_RS23850 (85888) | 85888..86616 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NML18_RS23855 (86603) | 86603..87169 | - | 567 | WP_202792315.1 | type IV conjugative transfer system protein TraE | - |
| NML18_RS23860 (87191) | 87191..87502 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NML18_RS23865 (87517) | 87517..87882 | - | 366 | WP_254837457.1 | type IV conjugative transfer system pilin TraA | - |
| NML18_RS23870 (87915) | 87915..88316 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| NML18_RS23875 (88409) | 88409..89098 | - | 690 | WP_254837473.1 | conjugal transfer transcriptional regulator TraJ | - |
| NML18_RS23880 (89285) | 89285..89668 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NML18_RS23885 (90001) | 90001..90591 | + | 591 | WP_175345273.1 | hypothetical protein | VF |
| NML18_RS23890 (90887) | 90887..91708 | - | 822 | WP_001234417.1 | DUF932 domain-containing protein | - |
| NML18_RS23895 (91827) | 91827..92114 | - | 288 | WP_000107542.1 | hypothetical protein | - |
| NML18_RS23900 (92139) | 92139..92345 | - | 207 | WP_000547965.1 | hypothetical protein | - |
| NML18_RS23905 (92415) | 92415..92711 | + | 297 | Protein_113 | hypothetical protein | - |
| NML18_RS23910 (93012) | 93012..93137 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NML18_RS23915 (93079) | 93079..93228 | - | 150 | Protein_115 | DUF5431 family protein | - |
| - (93235) | 93235..93433 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (93235) | 93235..93433 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (93235) | 93235..93433 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (93235) | 93235..93433 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| NML18_RS23920 (93402) | 93402..94164 | - | 763 | Protein_116 | plasmid SOS inhibition protein A | - |
| NML18_RS23925 (94161) | 94161..94595 | - | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| NML18_RS23930 (94650) | 94650..96608 | - | 1959 | WP_000117173.1 | ParB/RepB/Spo0J family partition protein | - |
| NML18_RS23935 (96674) | 96674..96907 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| NML18_RS23940 (96964) | 96964..97503 | - | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| NML18_RS23945 (97821) | 97821..98330 | + | 510 | WP_071594366.1 | hypothetical protein | - |
| NML18_RS23950 (98300) | 98300..98491 | - | 192 | WP_254837458.1 | hypothetical protein | - |
| NML18_RS23955 (98488) | 98488..98910 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| NML18_RS23960 (98957) | 98957..99382 | - | 426 | WP_001198920.1 | antirestriction protein | - |
| NML18_RS23965 (99796) | 99796..100572 | - | 777 | WP_001005032.1 | hypothetical protein | - |
| NML18_RS23970 (100618) | 100618..101172 | - | 555 | WP_001358893.1 | DUF1380 family protein | - |
| NML18_RS23975 (101066) | 101066..101287 | - | 222 | WP_001104904.1 | hypothetical protein | - |
| NML18_RS23980 (101288) | 101288..101971 | - | 684 | WP_000085939.1 | DNA methylase | - |
| NML18_RS23985 (102048) | 102048..102353 | - | 306 | WP_010892536.1 | hypothetical protein | - |
| NML18_RS23990 (102357) | 102357..103258 | - | 902 | Protein_130 | DUF1281 domain-containing protein | - |
| NML18_RS23995 (104082) | 104082..105053 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NML18_RS24000 (105053) | 105053..106219 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| NML18_RS24005 (106807) | 106807..107418 | - | 612 | WP_001764088.1 | replication initiation protein RepE | - |
| NML18_RS24010 (107543) | 107543..108631 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| NML18_RS24015 (108633) | 108633..110858 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| NML18_RS24020 (110908) | 110908..111807 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| NML18_RS24025 (111797) | 111797..112087 | - | 291 | WP_000538310.1 | hypothetical protein | - |
| NML18_RS24030 (114202) | 114202..114843 | + | 642 | WP_000990665.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|