MGE detailed information
MGE type: Conjugative plasmid MGE length: 120601 bp
Accession: NZ_CP075633 Location: 1..120601 Organism: Escherichia coli strain 2018-166 Replicon: plasmid pSTEC2018_166-a
Accession: NZ_CP075633 Location: 1..120601 Organism: Escherichia coli strain 2018-166 Replicon: plasmid pSTEC2018_166-a
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JFX80_RS25700 (1) | 1..858 | + | 858 | WP_062863644.1 | incFII family plasmid replication initiator RepA | - |
| JFX80_RS25705 (1794) | 1794..2123 | + | 330 | WP_000493283.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JFX80_RS25710 (2104) | 2104..2385 | + | 282 | WP_000780223.1 | helix-turn-helix transcriptional regulator | - |
| JFX80_RS25715 (2568) | 2568..2852 | + | 285 | WP_024166087.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| JFX80_RS25720 (2852) | 2852..3127 | + | 276 | WP_000421251.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| JFX80_RS25725 (3567) | 3567..3713 | + | 147 | Protein_5 | IS21 family transposase ISEc12 | Transposase |
| JFX80_RS25730 (3902) | 3902..5084 | - | 1183 | Protein_6 | IS91 family transposase | - |
| JFX80_RS25735 (5532) | 5532..5801 | + | 270 | Protein_7 | iron-regulated protein | - |
| JFX80_RS25740 (5809) | 5809..6585 | + | 777 | WP_000981087.1 | energy transducer TonB | - |
| JFX80_RS25745 (6754) | 6754..9015 | + | 2262 | WP_001100766.1 | TonB-dependent receptor | - |
| JFX80_RS25750 (9084) | 9084..10259 | + | 1176 | WP_001020415.1 | putative protein YncE | VF |
| JFX80_RS25755 (10889) | 10889..11347 | - | 459 | Protein_11 | IS110 family transposase | - |
| JFX80_RS25760 (11787) | 11787..12173 | - | 387 | WP_000673981.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| JFX80_RS25765 (12170) | 12170..12394 | - | 225 | WP_000493532.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| JFX80_RS25770 (12460) | 12460..12815 | + | 356 | Protein_14 | Tn3 family transposase | - |
| JFX80_RS25775 (13263) | 13263..14450 | - | 1188 | WP_198775086.1 | IS91 family transposase IS91 | Transposase |
| JFX80_RS25780 (14450) | 14450..14815 | - | 366 | WP_198775084.1 | hypothetical protein | - |
| JFX80_RS25790 (15038) | 15038..15328 | + | 291 | WP_001367320.1 | colicin K immunity protein | - |
| JFX80_RS25795 (15464) | 15464..15912 | + | 449 | Protein_18 | colicin immunity protein Cui | - |
| JFX80_RS25800 (15935) | 15935..17431 | - | 1497 | WP_001040753.1 | colicin-like pore-forming protein | - |
| JFX80_RS25805 (17671) | 17671..17961 | + | 291 | WP_000047032.1 | hypothetical protein | - |
| JFX80_RS25810 (17953) | 17953..18231 | - | 279 | WP_000710675.1 | hypothetical protein | - |
| JFX80_RS25815 (18353) | 18353..18775 | + | 423 | WP_021539380.1 | Exc2 family lipoprotein | - |
| JFX80_RS25820 (19172) | 19172..20290 | + | 1119 | WP_032308900.1 | MFS transporter | - |
| JFX80_RS25825 (20287) | 20287..21510 | + | 1224 | WP_024178282.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| JFX80_RS25830 (21581) | 21581..21727 | - | 147 | WP_001367303.1 | hypothetical protein | - |
| JFX80_RS25835 (22195) | 22195..23340 | - | 1146 | WP_000706385.1 | glycerate kinase | - |
| JFX80_RS25840 (23348) | 23348..24616 | - | 1269 | WP_000253684.1 | SLC13 family permease | - |
| JFX80_RS25845 (24736) | 24736..25875 | - | 1140 | WP_001033384.1 | sugar diacid recognition domain-containing protein | - |
| JFX80_RS25850 (26021) | 26021..26376 | - | 356 | Protein_29 | ISKra4 family transposase | - |
| JFX80_RS25855 (26380) | 26380..26742 | - | 363 | Protein_30 | 3'-5' exonuclease | - |
| JFX80_RS25860 (26975) | 26975..27181 | - | 207 | WP_163445145.1 | hypothetical protein | - |
| JFX80_RS25865 (27640) | 27640..28056 | - | 417 | WP_000275620.1 | type II toxin-antitoxin system VapC family toxin | - |
| JFX80_RS25870 (28056) | 28056..28310 | - | 255 | WP_000705662.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | - |
| JFX80_RS25875 (28470) | 28470..28937 | + | 468 | WP_001562850.1 | hypothetical protein | - |
| JFX80_RS25880 (29195) | 29195..29389 | + | 195 | WP_001367294.1 | ANR family transcriptional regulator | - |
| JFX80_RS25885 (31072) | 31072..32610 | - | 1539 | WP_000998048.1 | IS66 family transposase ISEc8 | Transposase |
| JFX80_RS25890 (32660) | 32660..33007 | - | 348 | WP_000612589.1 | IS66 family transposase ISEc8 | Transposase |
| JFX80_RS25895 (33004) | 33004..33384 | - | 381 | WP_001171530.1 | IS66 family transposase ISEc8 | Transposase |
| JFX80_RS25900 (34027) | 34027..35718 | + | 1692 | WP_000229015.1 | DUF2235 domain-containing protein | - |
| JFX80_RS25905 (35729) | 35729..36433 | + | 705 | WP_001253651.1 | DUF2931 family protein | - |
| JFX80_RS25910 (37099) | 37099..37560 | + | 462 | Protein_41 | IS66 family transposase ISCro1 | Transposase |
| JFX80_RS25915 (38404) | 38404..42738 | + | 4335 | WP_001053447.1 | Autotransporter adhesin SadA | VF |
| JFX80_RS25920 (42763) | 42763..43536 | + | 774 | WP_000899430.1 | Outer membrane protein A | VF |
| JFX80_RS25925 (43853) | 43853..44368 | + | 516 | WP_000839945.1 | RTX-I toxin-activating lysine-acyltransferase ApxIC | VF |
| JFX80_RS25930 (44370) | 44370..47366 | + | 2997 | WP_000217746.1 | Hemolysin, chromosomal | VF |
| JFX80_RS25935 (47416) | 47416..49536 | + | 2121 | WP_072193409.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| JFX80_RS25940 (49540) | 49540..50979 | + | 1440 | WP_001213535.1 | Hemolysin secretion protein D, chromosomal | VF |
| JFX80_RS27475 (51064) | 51064..51265 | + | 202 | Protein_48 | transcriptional regulator | - |
| JFX80_RS25945 (51276) | 51276..51644 | + | 369 | WP_001367346.1 | Transcriptional repressor MprA | VF |
| JFX80_RS25950 (51767) | 51767..52995 | + | 1229 | WP_169073214.1 | IS3 family transposase IS2 | Transposase |
| JFX80_RS25955 (53068) | 53068..53298 | + | 231 | WP_032286192.1 | hypothetical protein | - |
| JFX80_RS25960 (53419) | 53419..54159 | + | 741 | WP_001066926.1 | IS91 family transposase ISMno23 | Transposase |
| JFX80_RS25965 (54444) | 54444..55076 | - | 633 | Protein_53 | RepB family plasmid replication initiator protein | - |
| JFX80_RS25970 (55263) | 55263..56450 | - | 1188 | WP_000937604.1 | IS91 family transposase ISEc37 | Transposase |
| JFX80_RS25975 (56450) | 56450..56815 | - | 366 | WP_000091308.1 | hypothetical protein | - |
| JFX80_RS25980 (56897) | 56897..59011 | - | 2115 | WP_252354387.1 | hypothetical protein | - |
| JFX80_RS25985 (59392) | 59392..59622 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| JFX80_RS25990 (59619) | 59619..60035 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JFX80_RS25995 (60110) | 60110..61675 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| JFX80_RS26000 (61660) | 61660..62682 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| JFX80_RS26010 (64013) | 64013..66214 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| JFX80_RS26015 (66240) | 66240..67573 | - | 1334 | Protein_63 | L-lysine N6-monooxygenase | VF |
| JFX80_RS26020 (67570) | 67570..69312 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| JFX80_RS26025 (69312) | 69312..70259 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| JFX80_RS26030 (70260) | 70260..71984 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| JFX80_RS26035 (72120) | 72120..73313 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| JFX80_RS26040 (73693) | 73693..74073 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| JFX80_RS26045 (74414) | 74414..74827 | - | 414 | Protein_69 | phosphopyruvate hydratase | - |
| JFX80_RS26050 (74825) | 74825..75082 | + | 258 | Protein_70 | Tn3 family transposase | - |
| JFX80_RS26055 (75316) | 75316..76173 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| JFX80_RS26060 (76170) | 76170..77027 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| JFX80_RS26065 (77024) | 77024..77851 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| JFX80_RS26070 (77851) | 77851..78765 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| JFX80_RS26075 (79038) | 79038..79403 | + | 366 | WP_000091308.1 | hypothetical protein | - |
| JFX80_RS26080 (79403) | 79403..80590 | + | 1188 | WP_000937604.1 | IS91 family transposase ISEc37 | Transposase |
| JFX80_RS26085 (80713) | 80713..82464 | + | 1752 | WP_252354386.1 | hypothetical protein | - |
| JFX80_RS26090 (82509) | 82509..82925 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JFX80_RS26095 (82922) | 82922..83152 | - | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| JFX80_RS26100 (83417) | 83417..83917 | + | 501 | WP_000528932.1 | HEPN family nuclease | - |
| JFX80_RS26105 (83930) | 83930..84703 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| JFX80_RS26110 (84870) | 84870..86003 | + | 1134 | Protein_82 | DUF3800 domain-containing protein | - |
| JFX80_RS26115 (86555) | 86555..86773 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| JFX80_RS26120 (86775) | 86775..87080 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JFX80_RS26125 (87081) | 87081..87887 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| JFX80_RS26130 (88661) | 88661..89416 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| JFX80_RS26135 (90004) | 90004..91170 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| JFX80_RS26140 (91170) | 91170..92141 | + | 972 | WP_000817035.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JFX80_RS26145 (93008) | 93008..93909 | + | 902 | Protein_89 | DUF1281 domain-containing protein | - |
| JFX80_RS26150 (93913) | 93913..94218 | + | 306 | WP_010891292.1 | hypothetical protein | - |
| JFX80_RS26155 (94295) | 94295..94978 | + | 684 | WP_000085939.1 | DNA methylase | - |
| JFX80_RS26160 (94979) | 94979..95200 | + | 222 | WP_001104870.1 | hypothetical protein | - |
| JFX80_RS26165 (95094) | 95094..95648 | + | 555 | WP_077248347.1 | DUF1380 family protein | - |
| JFX80_RS26170 (95694) | 95694..96470 | + | 777 | WP_001005035.1 | hypothetical protein | - |
| JFX80_RS26175 (96883) | 96883..97308 | + | 426 | WP_001198918.1 | antirestriction protein | - |
| JFX80_RS26180 (97355) | 97355..97777 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| JFX80_RS26185 (97774) | 97774..97965 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| JFX80_RS26190 (97935) | 97935..98462 | - | 528 | WP_033806434.1 | hypothetical protein | - |
| JFX80_RS26195 (98532) | 98532..98738 | + | 207 | WP_000547940.1 | hypothetical protein | - |
| JFX80_RS26200 (98763) | 98763..99050 | + | 288 | WP_062863642.1 | hypothetical protein | - |
| JFX80_RS26205 (99169) | 99169..99990 | + | 822 | WP_001234490.1 | DUF932 domain-containing protein | - |
| JFX80_RS26210 (100286) | 100286..100888 | - | 603 | WP_001368286.1 | hypothetical protein | VF |
| JFX80_RS26215 (101211) | 101211..101594 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| JFX80_RS26220 (101784) | 101784..102470 | + | 687 | WP_000332492.1 | PAS domain-containing protein | - |
| JFX80_RS26225 (102564) | 102564..102791 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| JFX80_RS26230 (102825) | 102825..103190 | + | 366 | WP_000340270.1 | type IV conjugative transfer system pilin TraA | - |
| JFX80_RS26235 (103205) | 103205..103516 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| JFX80_RS26240 (103538) | 103538..104104 | + | 567 | WP_000399798.1 | type IV conjugative transfer system protein TraE | - |
| JFX80_RS26245 (104091) | 104091..104339 | + | 249 | Protein_109 | type-F conjugative transfer system secretin TraK | - |
| JFX80_RS26250 (104337) | 104337..105305 | + | 969 | Protein_110 | conjugal transfer protein TraG | - |
| JFX80_RS26255 (105302) | 105302..105811 | + | 510 | WP_000628105.1 | conjugal transfer entry exclusion protein TraS | - |
| JFX80_RS26260 (105825) | 105825..106556 | + | 732 | WP_000850423.1 | conjugal transfer complement resistance protein TraT | - |
| JFX80_RS26265 (106808) | 106808..108961 | + | 2154 | WP_053879280.1 | type IV conjugative transfer system coupling protein TraD | - |
| JFX80_RS26270 (108970) | 108970..109368 | - | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JFX80_RS26275 (109368) | 109368..109595 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| JFX80_RS26280 (109677) | 109677..114947 | + | 5271 | WP_000986967.1 | Multifunctional conjugation protein TraI | Relaxase |
| JFX80_RS26285 (114967) | 114967..115713 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| JFX80_RS26290 (115772) | 115772..116632 | + | 861 | WP_000704512.1 | putative protein YcjY | VF |
| JFX80_RS26295 (116735) | 116735..117292 | + | 558 | WP_000139316.1 | fertility inhibition protein FinO | - |
| JFX80_RS26300 (117446) | 117446..117649 | + | 204 | WP_001336517.1 | hypothetical protein | - |
| JFX80_RS26305 (118391) | 118391..118852 | + | 462 | WP_000760081.1 | thermonuclease family protein | - |
| JFX80_RS26310 (118940) | 118940..119338 | + | 399 | WP_000675594.1 | hypothetical protein | - |
| - (119513) | 119513..119569 | - | 57 | NuclAT_0 | - | Antitoxin Detail |
| - (119513) | 119513..119569 | - | 57 | NuclAT_0 | - | Antitoxin Detail |
| - (119513) | 119513..119569 | - | 57 | NuclAT_0 | - | Antitoxin Detail |
| - (119513) | 119513..119569 | - | 57 | NuclAT_0 | - | Antitoxin Detail |
| JFX80_RS26315 (119618) | 119618..119767 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| JFX80_RS26320 (120051) | 120051..120311 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| JFX80_RS27480 (120404) | 120404..120589 | + | 186 | Protein_125 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|